Crystal structure of the complex of hyaluranidase trimer with ascorbic acid at 3.1 A resolution reveals the locations of three binding sites

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Sequence of
7    ​L​​R​​V​​Q​​F​​K​​R​​M​​K​​A​17   ​A​​E​​W​​A​​R​​S​​D​​V​​I​​L​27   ​L​​E​​S​​E​​I​​G​​F​​E​​T​​D​37   ​T​​G​​F​​A​​R​​A​​G​​D​​G​​H​47   ​N​​R​​F​​S​​D​​L​​G​​Y​​I​​S​57   ​P​​L​​D​​Y​​N​​L​​L​​T​​N​​K​67   ​P​​N​​I​​D​​G​​L​​A​​T​​K​​V​77   ​E​​T​​A​​Q​​K​​L​​Q​​Q​​K​​A​87   ​D​​K​​E​​T​​V​​Y​​T​​K​​A​​E​97   ​S​​K​​Q​​E​​L​​D​​K​​K​​L​​N​107  ​L​​K​​G​​G​​V​​M​​T​​G​​Q​​L​117  ​K​​F​​K​​P​​A​​A​​T​​V​​A​​Y​127  ​S​​S​​S​​T​​G​​G​​A​​V​​N​​I​137  ​D​​L​​S​​S​​T​​R​​G​​A​​G​​V​147  ​V​​V​​Y​​S​​D​​N​​D​​T​​S​​D​157  ​G​​P​​L​​M​​S​​L​​R​​T​​G​​K​167  ​E​​T​​F​​N​​Q​​S​​A​​L​​F​​V​177  ​D​​Y​​K​​G​​T​​T​​N​​A​​V​​N​187  ​I​​A​​M​​R​​Q​​P​​T​​T​​P​​N​197  ​F​​S​​S​​A​​L​​N​​I​​T​​S​​G​207  ​N​​E​​N​​G​​S​​A​​M​​Q​​L​​R​217  ​G​​S​​E​​K​​A​​L​​G​​T​​L​​K​227  ​I​​T​​H​​E​​N​​P​​S​​I​​G​​A​237  ​D​​Y​​D​​K​​N​​A​​A​​A​​L​​S​247  ​I​​D​​I​​V​​K​​K​​T​​N​​G​​A​257  ​G​​T​​A​​A​​Q​​G​​I​​Y​​I​​N​267  ​S​​T​​S​​G​​T​​T​​G​​K​​L​​L​277  ​R​​I​​R​​N​​L​​S​​D​​D​​K​​F​287  ​Y​​V​​K​​S​​D​​G​​G​​F​​Y​​A​297  ​K​​E​​T​​S​​Q​​I​​D​​G​​N​​L​307  ​K​​L​​K​​D​​P​​T​​A​​N​​D​​H​317  ​A​​A​​T​​K​​A​​Y​​V​​D​​K​​A​327  ​I​​S​​E​​L​​K​​K​​L​​I​​L​​K​337  ​K​​H​
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