Crystal structure of the Fab fragment of necitumumab (Fab11F8) in complex with domain III from a cetuximab resistant variant of EGFR (sEGFRd3-S468R)

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RCSB PDB Mol* Viewer 2.11.4 [4/4/2025, 6:48:47 PM]
Sequence of
     ​L​​E​​E​​K​​K​​V​​C​​N​​G​​I​317  ​G​​I​​G​​E​​F​​K​​D​​S​​L​​S​327  ​I​​N​​A​​T​​N​​I​​K​​H​​F​​K​337  ​N​​C​​T​​S​​I​​S​​G​​D​​L​​H​347  ​I​​L​​P​​V​​A​​F​​R​​G​​D​​S​357  ​F​​T​​H​​T​​P​​P​​L​​D​​P​​Q​367  ​E​​L​​D​​I​​L​​K​​T​​V​​K​​E​377  ​I​​T​​G​​F​​L​​L​​I​​Q​​A​​W​387  ​P​​E​​N​​R​​T​​D​​L​​H​​A​​F​397  ​E​​N​​L​​E​​I​​I​​R​​G​​R​​T​407  ​K​​Q​​H​​G​​Q​​F​​S​​L​​A​​V​417  ​V​​S​​L​​N​​I​​T​​S​​L​​G​​L​427  ​R​​S​​L​​K​​E​​I​​S​​D​​G​​D​437  ​V​​I​​I​​S​​G​​N​​K​​N​​L​​C​447  ​Y​​A​​N​​T​​I​​N​​W​​K​​K​​L​457  ​F​​G​​T​​S​​G​​Q​​K​​T​​K​​I​467  ​I​​R​​N​​R​​G​​E​​N​​S​​C​​K​477  ​A​​T​​G​​Q​​V​​C​​H​​A​​L​​C​487  ​S​​P​​E​​G​​C​​W​​G​​P​​E​​P​497  ​R​​D​​C​​V​​S​​C​​R​​N​​V​​S​     ​R​​G​​R​​E​​C​​V​​D​​K​​H​​H​     ​H​​H​​H​​H​
Type
Asm Id
Dynamic Bonds

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