Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa

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3    ​S​​M​​L​​W​​V​​G​​V​​V​​S​​I​13   ​F​​P​​E​​M​​F​​R​​A​​I​​S​​D​23   ​Y​​G​​I​​T​​S​​R​​A​​V​​K​​Q​33   ​G​​L​​L​​T​​L​​T​​C​​W​​N​​P​43   ​R​​V​​Y​​T​​E​​D​​R​​H​​Q​​T​53   ​V​​D​​D​​R​​P​​F​​G​​G​​G​​P​63   ​G​​M​​V​​M​​K​​I​​K​​P​​L​​E​73   ​G​​A​​L​​A​​D​​A​​R​​Q​​A​​A​83   ​G​​G​​R​​K​​A​​K​​V​​I​​Y​​L​93   ​S​​P​​Q​​G​​R​​Q​​L​​T​​Q​​A​103  ​G​​V​​R​​E​​L​​A​​E​​E​​E​​A​113  ​L​​I​​L​​I​​A​​G​​R​​Y​​E​​G​123  ​I​​D​​E​​R​​F​​I​​E​​E​​H​​V​133  ​D​​E​​E​​W​​S​​I​​G​​D​​Y​​V​143  ​L​​S​​G​​G​​E​​L​​P​​A​​M​​V​153  ​L​​V​​D​​A​​V​​T​​R​​L​​L​​P​163  ​G​​A​​L​​G​​H​​A​​D​​S​​A​​E​173  ​E​​D​​S​​F​​T​​D​​G​​L​​L​​D​183  ​C​​P​​H​​Y​​T​​R​​P​​E​​V​​Y​193  ​A​​D​​K​​R​​V​​P​​E​​V​​L​​L​203  ​S​​G​​N​​H​​E​​H​​I​​R​​R​​W​213  ​R​​L​​Q​​Q​​A​​L​​G​​R​​T​​W​223  ​E​​R​​R​​A​​D​​L​​L​​D​​S​​R​233  ​S​​L​​S​​G​​E​​E​​Q​​K​​L​​L​243  ​A​​E​​Y​​I​​R​​Q​​R​​D​​D​​S​
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