D2 DOMAIN OF N-ETHYLMALEIMIDE-SENSITIVE FUSION PROTEIN
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d1d2na_ | Alpha and beta proteins (a/b) | P-loop containing nucleoside triphosphate hydrolases | P-loop containing nucleoside triphosphate hydrolases | Extended AAA-ATPase domain | Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein | Chinese hamster (Cricetulus griseus ) [TaxId: 10029 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | KOG0741 | e1d2nA2 | A: alpha arrays | X: Histone-like | H: Histone-related | T: AAA+ ATPase lid domain | F: KOG0741 | ECOD (1.6) |
A | AAA_11_1 | e1d2nA3 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: AAA_11_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (4.3.0) |
A | 1.10.8.60 | Mainly Alpha | Orthogonal Bundle | Helicase, Ruva Protein | domain 3 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00004 | ATPase family associated with various cellular activities (AAA) (AAA) | ATPase family associated with various cellular activities (AAA) | AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes [2]. | Domain | |
PF21964 | NSF, AAA+ ATPase lid domain (NSF_ATPase_lid) | NSF, AAA+ ATPase lid domain | This entry represents the ATPase lid domain of the second AAA+ ATP-binding domain (also known as D2) of NSF proteins [1], found at the C-terminal. NFS proteins are essential membrane fusion events. They play the role of a chaperone by activating SNAP ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR004201 | CDC48, domain 2 | Domain | |
IPR009010 | Aspartate decarboxylase-like domain superfamily | Homologous Superfamily | |
IPR003593 | AAA+ ATPase domain | Domain | |
IPR003959 | ATPase, AAA-type, core | Domain | |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Homologous Superfamily | |
IPR029067 | CDC48 domain 2-like superfamily | Homologous Superfamily | |
IPR041569 | AAA ATPase, AAA+ lid domain | Domain | |
IPR039812 | Vesicle-fusing ATPase | Family | |
IPR054419 | NSF, AAA+ ATPase lid domain | Domain | |
IPR003960 | ATPase, AAA-type, conserved site | Conserved Site | |
IPR003338 | CDC48, N-terminal subdomain | Domain |