1GP2
G PROTEIN HETEROTRIMER GI_ALPHA_1 BETA_1 GAMMA_2 WITH GDP BOUND
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | WD40 repeat-like | 8042849 | 3001694 | SCOP2B (2022-06-29) |
C [auth G] | SCOP2B Superfamily | Transducin (heterotrimeric G protein), gamma chain | 8070796 | 3001771 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Galpha insert domain-like | 8056777 | 3000669 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Ras-like P-loop GTPases | 8019719 | 3002022 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Ras-like P-loop GTPases | 8019719 | 3002022 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | ANAPC4_WD40_3 | e1gp2B1 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 7-bladed | F: ANAPC4_WD40_3 | ECOD (1.6) |
C [auth G] | G-gamma | e1gp2G1 | A: extended segments | X: Transducin (heterotrimeric G protein), gamma chain (From Topology) | H: Transducin (heterotrimeric G protein), gamma chain (From Topology) | T: Transducin (heterotrimeric G protein), gamma chain | F: G-gamma | ECOD (1.6) |
A | G-alpha | e1gp2A1 | A: alpha arrays | X: Transducin (alpha subunit), insertion domain (From Topology) | H: Transducin (alpha subunit), insertion domain (From Topology) | T: Transducin (alpha subunit), insertion domain | F: G-alpha | ECOD (1.6) |
A | Ras | e1gp2A2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: Ras | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 2.130.10.10 | Mainly Beta | 7 Propeller | Methylamine Dehydrogenase | Chain H | CATH (4.3.0) |
C [auth G] | 4.10.260.10 | Few Secondary Structures | Irregular | G Protein Gi Gamma 2 | Transducin (heterotrimeric G protein), gamma chain | CATH (4.3.0) |
A | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (4.3.0) |
A | 1.10.400.10 | Mainly Alpha | Orthogonal Bundle | GI Alpha 1, domain 2-like | GI Alpha 1, domain 2-like | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat | |
PF00503 | G-protein alpha subunit (G-alpha) | G-protein alpha subunit | G proteins couple receptors of extracellular signals to intracellular signaling pathways. The G protein alpha subunit binds guanyl nucleotide and is a weak GTPase. A set of residues that are unique to G-alpha as compared to its ancestor the Arf-like ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR019775 | WD40 repeat, conserved site | Conserved Site | |
IPR016346 | Guanine nucleotide-binding protein, beta subunit | Family | |
IPR036322 | WD40-repeat-containing domain superfamily | Homologous Superfamily | |
IPR001632 | G-protein, beta subunit | Domain | |
IPR001680 | WD40 repeat | Repeat | |
IPR020472 | G-protein beta WD-40 repeat | Repeat | |
IPR015943 | WD40/YVTN repeat-like-containing domain superfamily | Homologous Superfamily | |
C [auth G] | IPR036284 | G-protein gamma-like domain superfamily | Homologous Superfamily |
C [auth G] | IPR015898 | G-protein gamma-like domain | Domain |
C [auth G] | IPR001770 | G-protein, gamma subunit | Family |
IPR001019 | Guanine nucleotide binding protein (G-protein), alpha subunit | Family | |
IPR011025 | G protein alpha subunit, helical insertion | Homologous Superfamily | |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Homologous Superfamily | |
IPR001408 | G-protein alpha subunit, group I | Family |