1I7Q | pdb_00001i7q

ANTHRANILATE SYNTHASE FROM S. MARCESCENS

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
D	d1i7qd_	Alpha and beta proteins (a/b)	Flavodoxin-like	Class I glutamine amidotransferase-like	Class I glutamine amidotransferases (GAT)	Anthranilate synthase GAT subunit, TrpG	(Serratia marcescens ) [TaxId: 615 ],	SCOPe (2.08)
B	d1i7qb_	Alpha and beta proteins (a/b)	Flavodoxin-like	Class I glutamine amidotransferase-like	Class I glutamine amidotransferases (GAT)	Anthranilate synthase GAT subunit, TrpG	(Serratia marcescens ) [TaxId: 615 ],	SCOPe (2.08)
C	d1i7qc_	Alpha and beta proteins (a+b)	ADC synthase	ADC synthase	ADC synthase	Anthranilate synthase aminodeoxyisochorismate synthase/lyase subunit, TrpE	(Serratia marcescens ) [TaxId: 615 ],	SCOPe (2.08)
A	d1i7qa_	Alpha and beta proteins (a+b)	ADC synthase	ADC synthase	ADC synthase	Anthranilate synthase aminodeoxyisochorismate synthase/lyase subunit, TrpE	(Serratia marcescens ) [TaxId: 615 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
D	SCOP2B Superfamily	Class I glutamine amidotransferase-like	8033742	3001405	SCOP2B (2022-06-29)
B	SCOP2 Family	Class I glutamine amidotransferases (GAT)	8021362	4003747	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Class I glutamine amidotransferase-like	8033742	3001405	SCOP2 (2022-06-29)
C	SCOP2B Superfamily	ADC synthase	8033740	3001093	SCOP2B (2022-06-29)
A	SCOP2 Family	ADC synthase	8021360	4002317	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	ADC synthase	8033740	3001093	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
D	GATase	e1i7qD1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Class I glutamine amidotransferase-like	F: GATase	ECOD (1.6)
B	GATase	e1i7qB1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Class I glutamine amidotransferase-like	F: GATase	ECOD (1.6)
C	Chorismate_bind	e1i7qC1	A: a+b duplicates or obligate multimers	X: ADC synthase (From Topology)	H: ADC synthase (From Topology)	T: ADC synthase	F: Chorismate_bind	ECOD (1.6)
A	Chorismate_bind	e1i7qA1	A: a+b duplicates or obligate multimers	X: ADC synthase (From Topology)	H: ADC synthase (From Topology)	T: ADC synthase	F: Chorismate_bind	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
D	3.40.50.880	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Class I glutamine amidotransferase (GATase) domain	CATH (4.3.0)
B	3.40.50.880	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Class I glutamine amidotransferase (GATase) domain	CATH (4.3.0)
C	3.60.120.10	Alpha Beta	4-Layer Sandwich	Anthranilate synthase	Anthranilate synthase	CATH (4.3.0)
A	3.60.120.10	Alpha Beta	4-Layer Sandwich	Anthranilate synthase	Anthranilate synthase	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B, D	TRPG	pentosyltransferase activity glycosyltransferase activity transferase activity anthranilate phosphoribosyltransferase activity catalytic activity oxo-acid-lyase activity lyase activity anthranilate synthase activity carbon-carbon lyase activity	antibiotic metabolic process biosynthetic process metabolic process cellular process phenazine biosynthetic process antibiotic biosynthetic process oxoacid metabolic process indole-containing compound metabolic process amino acid metabolic process organic acid biosynthetic process organic acid metabolic process alpha-amino acid metabolic process carboxylic acid biosynthetic process biogenic amine biosynthetic process antibiotic metabolic process biosynthetic process metabolic process cellular process phenazine biosynthetic process antibiotic biosynthetic process oxoacid metabolic process indole-containing compound metabolic process amino acid metabolic process organic acid biosynthetic process organic acid metabolic process alpha-amino acid metabolic process carboxylic acid biosynthetic process biogenic amine biosynthetic process indole-containing compound biosynthetic process L-tryptophan metabolic process small molecule metabolic process indolalkylamine biosynthetic process aromatic amino acid family biosynthetic process aromatic amino acid metabolic process small molecule biosynthetic process carboxylic acid metabolic process primary metabolic process L-amino acid biosynthetic process L-amino acid metabolic process L-tryptophan biosynthetic process proteinogenic amino acid metabolic process amine metabolic process amino acid biosynthetic process amine biosynthetic process proteinogenic amino acid biosynthetic process erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process biogenic amine metabolic process alpha-amino acid biosynthetic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol
A, C	ANTHRANILATE SYNTHASE	cation binding ion binding binding metal ion binding small molecule binding oxo-acid-lyase activity lyase activity anthranilate synthase activity catalytic activity carbon-carbon lyase activity	oxoacid metabolic process indole-containing compound metabolic process amino acid metabolic process organic acid biosynthetic process organic acid metabolic process alpha-amino acid metabolic process carboxylic acid biosynthetic process biogenic amine biosynthetic process indole-containing compound biosynthetic process L-tryptophan metabolic process small molecule metabolic process indolalkylamine biosynthetic process aromatic amino acid family biosynthetic process aromatic amino acid metabolic process oxoacid metabolic process indole-containing compound metabolic process amino acid metabolic process organic acid biosynthetic process organic acid metabolic process alpha-amino acid metabolic process carboxylic acid biosynthetic process biogenic amine biosynthetic process indole-containing compound biosynthetic process L-tryptophan metabolic process small molecule metabolic process indolalkylamine biosynthetic process aromatic amino acid family biosynthetic process aromatic amino acid metabolic process small molecule biosynthetic process carboxylic acid metabolic process primary metabolic process L-amino acid biosynthetic process L-amino acid metabolic process L-tryptophan biosynthetic process proteinogenic amino acid metabolic process amine metabolic process amino acid biosynthetic process biosynthetic process amine biosynthetic process proteinogenic amino acid biosynthetic process metabolic process cellular process erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process biogenic amine metabolic process alpha-amino acid biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B, D	IPR029062	Class I glutamine amidotransferase-like	Homologous Superfamily
B, D	IPR017926	Glutamine amidotransferase	Domain
B, D	IPR006221	Anthranilate synthase/para-aminobenzoate synthase like domain	Domain
B, D	IPR050472	Anthranilate Synthase/Amidotransferase	Family
A, C	IPR019999	Anthranilate synthase component I-like	Family
A, C	IPR005257	Anthranilate synthase component I, TrpE-like, bacterial	Family
A, C	IPR015890	Chorismate-utilising enzyme, C-terminal	Domain
A, C	IPR006805	Anthranilate synthase component I, N-terminal	Domain
A, C	IPR005801	ADC synthase	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.