1IX2 | pdb_00001ix2

Crystal Structure of Selenomethionine PcoC, a Copper Resistance Protein from Escherichia coli

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1ix2a_	All beta proteins	Immunoglobulin-like beta-sandwich	E set domains	Copper resistance protein C (CopC, PcoC)	Copper resistance protein C (CopC, PcoC)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d1ix2b_	All beta proteins	Immunoglobulin-like beta-sandwich	E set domains	Copper resistance protein C (CopC, PcoC)	Copper resistance protein C (CopC, PcoC)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Copper resistance protein C (CopC, PcoC)	8055058	4007550	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	E set domains	8055059	3000070	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	E set domains	8055059	3000070	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	CopC	e1ix2A1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: CopC	ECOD (1.6)
B	CopC	e1ix2B1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: CopC	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.40.1220	Mainly Beta	Sandwich	Immunoglobulin-like		CATH (4.3.0)
B	2.60.40.1220	Mainly Beta	Sandwich	Immunoglobulin-like		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF04234	CopC domain (CopC)	CopC domain	CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule. Along with CopA, CopC mediates copper resistance by sequestration of copper in the periplasm [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	PcoC copper resistance protein	cation binding transition metal ion binding copper ion binding ion binding binding metal ion binding small molecule binding	response to copper ion response to stimulus response to metal ion response to chemical localization transport copper ion transport transition metal ion transport monoatomic ion transport monoatomic cation transport establishment of localization metal ion transport	cell periphery cellular anatomical structure plasma membrane membrane periplasmic space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR014756	Immunoglobulin E-set	Homologous Superfamily
A, B	IPR047685	Copper resistance protein CopC-like	Family
A, B	IPR007348	CopC domain	Domain
A, B	IPR032694	Copper transport protein C/D	Family
A, B	IPR014755	Copper resistance protein CopC/internalin, immunoglobulin-like	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.