1OKI | pdb_00001oki

Crystal structure of truncated human beta-B1-crystallin

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Pharos: Disease Associations
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d1okib1	All beta proteins	gamma-Crystallin-like	gamma-Crystallin-like	Crystallins/Ca-binding development proteins	beta-Crystallin	HUMAN (Homo sapiens ) [TaxId: 9606 ],	SCOPe (2.08)
A	d1okia1	All beta proteins	gamma-Crystallin-like	gamma-Crystallin-like	Crystallins/Ca-binding development proteins	beta-Crystallin	HUMAN (Homo sapiens ) [TaxId: 9606 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	gamma-Crystallin-like	8037585	3001138	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	gamma-Crystallin-like	8037587	3001138	SCOP2B (2022-06-29)
A	SCOP2 Family	Crystallins/Ca-binding development proteins	8025206	4002359	SCOP2 (2022-06-29)
A	SCOP2 Family	Crystallins/Ca-binding development proteins	8025208	4002359	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	gamma-Crystallin-like	8037585	3001138	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	gamma-Crystallin-like	8037587	3001138	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	Crystall	e1okiB1	A: beta sandwiches	X: gamma-Crystallin-like (From Topology)	H: gamma-Crystallin-like (From Topology)	T: gamma-Crystallin-like	F: Crystall	ECOD (1.6)
A	Crystall	e1okiA1	A: beta sandwiches	X: gamma-Crystallin-like (From Topology)	H: gamma-Crystallin-like (From Topology)	T: gamma-Crystallin-like	F: Crystall	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.60.20.10	Mainly Beta	Sandwich	Gamma-B Crystallin	domain 1	CATH (4.3.0)
A	2.60.20.10	Mainly Beta	Sandwich	Gamma-B Crystallin	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00030	Beta/Gamma crystallin (Crystall)	Beta/Gamma crystallin	The alignment comprises two Greek key motifs since the similarity between them is very low.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	BETA CRYSTALLIN B1	structural molecule activity structural constituent of eye lens	developmental process multicellular organismal process sensory organ development eye development animal organ development visual system development multicellular organism development camera-type eye development anatomical structure development sensory system development lens development in camera-type eye system development sensory perception of light stimulus system process developmental process multicellular organismal process sensory organ development eye development animal organ development visual system development multicellular organism development camera-type eye development anatomical structure development sensory system development lens development in camera-type eye system development sensory perception of light stimulus system process sensory perception nervous system process visual perception	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR001064	Beta/gamma crystallin	Domain
A, B	IPR011024	Gamma-crystallin-like	Homologous Superfamily
A, B	IPR050252	Beta/Gamma-Crystallin	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A, B	Pharos: P53674	cataract cataract 17 multiple types pulverulent cataract CATARACT 17, MULTIPLE TYPES cataract - microcornea syndrome nuclear cataract intellectual disability

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, B	CSD	Parent Component: CYS RESID: AA0262 PSI-MOD : L-cysteine sulfinic acid MOD:00267

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.