2B1E | pdb_00002b1e

The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2b1ea_	All alpha proteins	alpha-alpha superhelix	Cullin repeat-like	Exocyst complex component	automated matches	baker's yeast (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Cullin repeat-like	8037698	3000059	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Exo70	e2b1eA1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: Exo70	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.58.1150	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)
A	1.20.1310.30	Mainly Alpha	Up-down Bundle	5 helical Cullin repeat like		CATH (4.3.0)
A	1.10.357.60	Mainly Alpha	Orthogonal Bundle	Tetracycline Repressor	domain 2	CATH (4.3.0)
A	1.20.1280.170	Mainly Alpha	Up-down Bundle	Monooxygenase	Exocyst complex component Exo70	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF03081	Exo70 exocyst complex subunit C-terminal (Exo70_C)	Exo70 exocyst complex subunit C-terminal	-	Repeat
A	PF20669	Exocyst complex component Exo70 N-terminal (Exo70_N)	Exocyst complex component Exo70 N-terminal	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Exocyst complex component EXO70	binding ion binding phosphatidylinositol-4,5-bisphosphate binding anion binding phosphatidylinositol bisphosphate binding phospholipid binding lipid binding phosphatidylinositol phosphate binding phosphatidylinositol binding small molecule binding small GTPase binding protein binding enzyme binding GTPase binding	Golgi to plasma membrane transport cellular localization post-Golgi vesicle-mediated transport transport localization within membrane establishment of localization vesicle-mediated transport vesicle-mediated transport to the plasma membrane localization cellular process Golgi vesicle transport protein-containing complex organization secretion exocyst assembly Golgi to plasma membrane transport cellular localization post-Golgi vesicle-mediated transport transport localization within membrane establishment of localization vesicle-mediated transport vesicle-mediated transport to the plasma membrane localization cellular process Golgi vesicle transport protein-containing complex organization secretion exocyst assembly export from cell membrane docking cellular component organization cellular component biogenesis organelle localization by membrane tethering cellular component assembly secretion by cell exocytosis organelle localization protein-containing complex assembly vesicle docking exocytic process cellular component organization or biogenesis vesicle docking involved in exocytosis protein localization establishment of protein localization nitrogen compound transport protein transport cellular macromolecule localization macromolecule localization exocyst localization protein-containing complex localization cellular response to stimulus regulation of biological process small GTPase-mediated signal transduction regulation of cellular process response to stimulus signaling biological regulation Rho protein signal transduction intracellular signal transduction cell communication intracellular signaling cassette signal transduction	cellular anatomical structure incipient cellular bud site site of polarized growth cellular bud cellular bud tip cell projection mating projection cell tip mating projection tip cell pole plasma membrane bounded cell projection cell periphery plasma membrane membrane cellular anatomical structure incipient cellular bud site site of polarized growth cellular bud cellular bud tip cell projection mating projection cell tip mating projection tip cell pole plasma membrane bounded cell projection cell periphery plasma membrane membrane ascospore-type prospore prospore membrane intracellular immature spore membrane-bounded organelle intracellular anatomical structure transport vesicle intracellular vesicle intracellular membrane-bounded organelle endomembrane system intracellular organelle cytoplasmic vesicle organelle cytoplasm vesicle cellular bud neck protein-containing complex cell cortex exocyst vesicle tethering complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR004140	Exocyst complex component Exo70	Family
A	IPR046364	Exocyst complex subunit Exo70, C-terminal	Domain
A	IPR016159	Cullin repeat-like-containing domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.