2GGE | pdb_00002gge

Crystal Structure of Mandelate Racemase/Muconate Lactonizing Enzyme from Bacillus Subtilis complexed with MG++ at 1.8 A

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2ggea1 Alpha and beta proteins (a/b) TIM beta/alpha-barrel Enolase C-terminal domain-like D-glucarate dehydratase-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Ad2ggea2 Alpha and beta proteins (a+b) Enolase N-terminal domain-like Enolase N-terminal domain-like Enolase N-terminal domain-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Ad2ggea4 Artifacts Tags Tags Tags C-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Ad2ggea3 Artifacts Tags Tags Tags N-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Bd2ggeb1 Alpha and beta proteins (a/b) TIM beta/alpha-barrel Enolase C-terminal domain-like D-glucarate dehydratase-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Bd2ggeb2 Alpha and beta proteins (a+b) Enolase N-terminal domain-like Enolase N-terminal domain-like Enolase N-terminal domain-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Bd2ggeb4 Artifacts Tags Tags Tags C-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Bd2ggeb3 Artifacts Tags Tags Tags N-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Cd2ggec1 Alpha and beta proteins (a/b) TIM beta/alpha-barrel Enolase C-terminal domain-like D-glucarate dehydratase-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Cd2ggec2 Alpha and beta proteins (a+b) Enolase N-terminal domain-like Enolase N-terminal domain-like Enolase N-terminal domain-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Cd2ggec4 Artifacts Tags Tags Tags C-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Cd2ggec3 Artifacts Tags Tags Tags N-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Dd2gged1 Alpha and beta proteins (a/b) TIM beta/alpha-barrel Enolase C-terminal domain-like D-glucarate dehydratase-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Dd2gged2 Alpha and beta proteins (a+b) Enolase N-terminal domain-like Enolase N-terminal domain-like Enolase N-terminal domain-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Dd2gged4 Artifacts Tags Tags Tags C-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Dd2gged3 Artifacts Tags Tags Tags N-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Ed2ggee1 Alpha and beta proteins (a/b) TIM beta/alpha-barrel Enolase C-terminal domain-like D-glucarate dehydratase-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Ed2ggee2 Alpha and beta proteins (a+b) Enolase N-terminal domain-like Enolase N-terminal domain-like Enolase N-terminal domain-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Ed2ggee4 Artifacts Tags Tags Tags C-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Ed2ggee3 Artifacts Tags Tags Tags N-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Fd2ggef1 Alpha and beta proteins (a/b) TIM beta/alpha-barrel Enolase C-terminal domain-like D-glucarate dehydratase-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Fd2ggef2 Alpha and beta proteins (a+b) Enolase N-terminal domain-like Enolase N-terminal domain-like Enolase N-terminal domain-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Fd2ggef4 Artifacts Tags Tags Tags C-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Fd2ggef3 Artifacts Tags Tags Tags N-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Gd2ggeg1 Alpha and beta proteins (a/b) TIM beta/alpha-barrel Enolase C-terminal domain-like D-glucarate dehydratase-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Gd2ggeg2 Alpha and beta proteins (a+b) Enolase N-terminal domain-like Enolase N-terminal domain-like Enolase N-terminal domain-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Gd2ggeg4 Artifacts Tags Tags Tags C-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Gd2ggeg3 Artifacts Tags Tags Tags N-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Hd2ggeh1 Alpha and beta proteins (a/b) TIM beta/alpha-barrel Enolase C-terminal domain-like D-glucarate dehydratase-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Hd2ggeh2 Alpha and beta proteins (a+b) Enolase N-terminal domain-like Enolase N-terminal domain-like Enolase N-terminal domain-like Hypothetical protein YitF (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Hd2ggeh4 Artifacts Tags Tags Tags C-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)
Hd2ggeh3 Artifacts Tags Tags Tags N-terminal Tags (Bacillus subtilis ) [TaxId: 1423 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyEnolase C-terminal domain-like 8041795 3000476 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyEnolase N-terminal domain-like 8041796 3001064 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyEnolase C-terminal domain-like 8041795 3000476 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyEnolase N-terminal domain-like 8041796 3001064 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyEnolase C-terminal domain-like 8041795 3000476 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyEnolase N-terminal domain-like 8041796 3001064 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyEnolase C-terminal domain-like 8041795 3000476 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyEnolase N-terminal domain-like 8041796 3001064 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyEnolase C-terminal domain-like 8041795 3000476 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyEnolase N-terminal domain-like 8041796 3001064 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyEnolase C-terminal domain-like 8041795 3000476 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyEnolase N-terminal domain-like 8041796 3001064 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyEnolase C-terminal domain-like 8041795 3000476 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyEnolase N-terminal domain-like 8041796 3001064 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyEnolase N-terminal domain-like 8041796 3001064 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyEnolase C-terminal domain-like 8041795 3000476 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AMR_MLE_Ne2ggeA1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Enolase N-terminal domain-like (From Topology)T: Enolase N-terminal domain-likeF: MR_MLE_NECOD (1.6)
AMR_MLE_Ce2ggeA2 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: MR_MLE_CECOD (1.6)
BMR_MLE_Ne2ggeB1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Enolase N-terminal domain-like (From Topology)T: Enolase N-terminal domain-likeF: MR_MLE_NECOD (1.6)
BMR_MLE_Ce2ggeB2 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: MR_MLE_CECOD (1.6)
CMR_MLE_Ne2ggeC1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Enolase N-terminal domain-like (From Topology)T: Enolase N-terminal domain-likeF: MR_MLE_NECOD (1.6)
CMR_MLE_Ce2ggeC2 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: MR_MLE_CECOD (1.6)
DMR_MLE_Ne2ggeD1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Enolase N-terminal domain-like (From Topology)T: Enolase N-terminal domain-likeF: MR_MLE_NECOD (1.6)
DMR_MLE_Ce2ggeD2 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: MR_MLE_CECOD (1.6)
EMR_MLE_Ne2ggeE1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Enolase N-terminal domain-like (From Topology)T: Enolase N-terminal domain-likeF: MR_MLE_NECOD (1.6)
EMR_MLE_Ce2ggeE2 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: MR_MLE_CECOD (1.6)
FMR_MLE_Ne2ggeF1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Enolase N-terminal domain-like (From Topology)T: Enolase N-terminal domain-likeF: MR_MLE_NECOD (1.6)
FMR_MLE_Ce2ggeF2 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: MR_MLE_CECOD (1.6)
GMR_MLE_Ne2ggeG1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Enolase N-terminal domain-like (From Topology)T: Enolase N-terminal domain-likeF: MR_MLE_NECOD (1.6)
GMR_MLE_Ce2ggeG2 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: MR_MLE_CECOD (1.6)
HMR_MLE_Ne2ggeH1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Enolase N-terminal domain-like (From Topology)T: Enolase N-terminal domain-likeF: MR_MLE_NECOD (1.6)
HMR_MLE_Ce2ggeH2 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: MR_MLE_CECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.30.390.10 Alpha Beta 2-Layer Sandwich Enolase-like domain 1CATH (4.3.0)
A3.20.20.120 Alpha Beta Alpha-Beta Barrel TIM Barrel Enolase-like C-terminal domainCATH (4.3.0)
B3.30.390.10 Alpha Beta 2-Layer Sandwich Enolase-like domain 1CATH (4.3.0)
B3.20.20.120 Alpha Beta Alpha-Beta Barrel TIM Barrel Enolase-like C-terminal domainCATH (4.3.0)
C3.30.390.10 Alpha Beta 2-Layer Sandwich Enolase-like domain 1CATH (4.3.0)
C3.20.20.120 Alpha Beta Alpha-Beta Barrel TIM Barrel Enolase-like C-terminal domainCATH (4.3.0)
D3.30.390.10 Alpha Beta 2-Layer Sandwich Enolase-like domain 1CATH (4.3.0)
D3.20.20.120 Alpha Beta Alpha-Beta Barrel TIM Barrel Enolase-like C-terminal domainCATH (4.3.0)
E3.30.390.10 Alpha Beta 2-Layer Sandwich Enolase-like domain 1CATH (4.3.0)
E3.20.20.120 Alpha Beta Alpha-Beta Barrel TIM Barrel Enolase-like C-terminal domainCATH (4.3.0)
F3.30.390.10 Alpha Beta 2-Layer Sandwich Enolase-like domain 1CATH (4.3.0)
F3.20.20.120 Alpha Beta Alpha-Beta Barrel TIM Barrel Enolase-like C-terminal domainCATH (4.3.0)
G3.30.390.10 Alpha Beta 2-Layer Sandwich Enolase-like domain 1CATH (4.3.0)
G3.20.20.120 Alpha Beta Alpha-Beta Barrel TIM Barrel Enolase-like C-terminal domainCATH (4.3.0)
H3.30.390.10 Alpha Beta 2-Layer Sandwich Enolase-like domain 1CATH (4.3.0)
H3.20.20.120 Alpha Beta Alpha-Beta Barrel TIM Barrel Enolase-like C-terminal domainCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF02746Mandelate racemase / muconate lactonizing enzyme, N-terminal domain (MR_MLE_N)Mandelate racemase / muconate lactonizing enzyme, N-terminal domainSCOP reports fold similarity with enolase N-terminal domain. Domain
A, B, C, D, E
PF13378Enolase C-terminal domain-like (MR_MLE_C)Enolase C-terminal domain-likeThis domain appears at the C-terminus of many of the proteins that carry the MR_MLE_N Pfam:PF02746 domain. EC:4.2.1.40. Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
yitF -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR029065Enolase C-terminal domain-likeDomain
A, B, C, D, E
IPR013341Mandelate racemase/muconate lactonizing enzyme, N-terminal domainDomain
A, B, C, D, E
IPR046945L-rhamnonate dehydratase-likeFamily
A, B, C, D, E
IPR013342Mandelate racemase/muconate lactonizing enzyme, C-terminalDomain
A, B, C, D, E
IPR029017Enolase-like, N-terminalHomologous Superfamily
A, B, C, D, E
IPR036849Enolase-like, C-terminal domain superfamilyHomologous Superfamily