Annotations: 2J58

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	SLBB	e2j58A2	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Nqo1 middle domain-like	F: SLBB	ECOD (1.6)
A	Poly_export	e2j58A1	A: a+b two layers	X: Domain 1 of outer membrane lipoprotein Wza (From Topology)	H: Domain 1 of outer membrane lipoprotein Wza (From Topology)	T: Domain 1 of outer membrane lipoprotein Wza	F: Poly_export	ECOD (1.6)
A	PRK15078	e2j58A4	A: extended segments	X: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	H: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	T: Transmembrane helix of outer membrane lipoprotein Wza	F: PRK15078	ECOD (1.6)
B	SLBB	e2j58B1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Nqo1 middle domain-like	F: SLBB	ECOD (1.6)
B	Poly_export	e2j58B2	A: a+b two layers	X: Domain 1 of outer membrane lipoprotein Wza (From Topology)	H: Domain 1 of outer membrane lipoprotein Wza (From Topology)	T: Domain 1 of outer membrane lipoprotein Wza	F: Poly_export	ECOD (1.6)
B	PRK15078	e2j58B3	A: extended segments	X: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	H: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	T: Transmembrane helix of outer membrane lipoprotein Wza	F: PRK15078	ECOD (1.6)
D	SLBB	e2j58D1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Nqo1 middle domain-like	F: SLBB	ECOD (1.6)
D	Poly_export	e2j58D2	A: a+b two layers	X: Domain 1 of outer membrane lipoprotein Wza (From Topology)	H: Domain 1 of outer membrane lipoprotein Wza (From Topology)	T: Domain 1 of outer membrane lipoprotein Wza	F: Poly_export	ECOD (1.6)
D	PRK15078	e2j58D3	A: extended segments	X: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	H: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	T: Transmembrane helix of outer membrane lipoprotein Wza	F: PRK15078	ECOD (1.6)
E	SLBB	e2j58E1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Nqo1 middle domain-like	F: SLBB	ECOD (1.6)
E	Poly_export	e2j58E2	A: a+b two layers	X: Domain 1 of outer membrane lipoprotein Wza (From Topology)	H: Domain 1 of outer membrane lipoprotein Wza (From Topology)	T: Domain 1 of outer membrane lipoprotein Wza	F: Poly_export	ECOD (1.6)
E	PRK15078	e2j58E3	A: extended segments	X: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	H: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	T: Transmembrane helix of outer membrane lipoprotein Wza	F: PRK15078	ECOD (1.6)
C	SLBB	e2j58C1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Nqo1 middle domain-like	F: SLBB	ECOD (1.6)
C	Poly_export	e2j58C2	A: a+b two layers	X: Domain 1 of outer membrane lipoprotein Wza (From Topology)	H: Domain 1 of outer membrane lipoprotein Wza (From Topology)	T: Domain 1 of outer membrane lipoprotein Wza	F: Poly_export	ECOD (1.6)
C	PRK15078	e2j58C3	A: extended segments	X: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	H: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	T: Transmembrane helix of outer membrane lipoprotein Wza	F: PRK15078	ECOD (1.6)
F	SLBB	e2j58F1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Nqo1 middle domain-like	F: SLBB	ECOD (1.6)
F	Poly_export	e2j58F2	A: a+b two layers	X: Domain 1 of outer membrane lipoprotein Wza (From Topology)	H: Domain 1 of outer membrane lipoprotein Wza (From Topology)	T: Domain 1 of outer membrane lipoprotein Wza	F: Poly_export	ECOD (1.6)
F	PRK15078	e2j58F3	A: extended segments	X: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	H: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	T: Transmembrane helix of outer membrane lipoprotein Wza	F: PRK15078	ECOD (1.6)
G	SLBB	e2j58G1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Nqo1 middle domain-like	F: SLBB	ECOD (1.6)
G	Poly_export	e2j58G2	A: a+b two layers	X: Domain 1 of outer membrane lipoprotein Wza (From Topology)	H: Domain 1 of outer membrane lipoprotein Wza (From Topology)	T: Domain 1 of outer membrane lipoprotein Wza	F: Poly_export	ECOD (1.6)
G	PRK15078	e2j58G3	A: extended segments	X: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	H: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	T: Transmembrane helix of outer membrane lipoprotein Wza	F: PRK15078	ECOD (1.6)
H	SLBB	e2j58H1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Nqo1 middle domain-like	F: SLBB	ECOD (1.6)
H	Poly_export	e2j58H2	A: a+b two layers	X: Domain 1 of outer membrane lipoprotein Wza (From Topology)	H: Domain 1 of outer membrane lipoprotein Wza (From Topology)	T: Domain 1 of outer membrane lipoprotein Wza	F: Poly_export	ECOD (1.6)
H	PRK15078	e2j58H3	A: extended segments	X: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	H: Transmembrane helix of outer membrane lipoprotein Wza (From Topology)	T: Transmembrane helix of outer membrane lipoprotein Wza	F: PRK15078	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.560.10	Alpha Beta	Roll	Outer membrane lipoprotein wza fold like	Outer membrane lipoprotein wza domain like	CATH (4.3.0)
A	3.30.1950.10	Alpha Beta	2-Layer Sandwich	wza like fold	wza like domain	CATH (4.3.0)
A	1.20.5.70	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
B	3.10.560.10	Alpha Beta	Roll	Outer membrane lipoprotein wza fold like	Outer membrane lipoprotein wza domain like	CATH (4.3.0)
B	3.30.1950.10	Alpha Beta	2-Layer Sandwich	wza like fold	wza like domain	CATH (4.3.0)
B	1.20.5.70	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
D	3.10.560.10	Alpha Beta	Roll	Outer membrane lipoprotein wza fold like	Outer membrane lipoprotein wza domain like	CATH (4.3.0)
D	3.30.1950.10	Alpha Beta	2-Layer Sandwich	wza like fold	wza like domain	CATH (4.3.0)
D	1.20.5.70	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
E	3.10.560.10	Alpha Beta	Roll	Outer membrane lipoprotein wza fold like	Outer membrane lipoprotein wza domain like	CATH (4.3.0)
E	3.30.1950.10	Alpha Beta	2-Layer Sandwich	wza like fold	wza like domain	CATH (4.3.0)
E	1.20.5.70	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
C	3.10.560.10	Alpha Beta	Roll	Outer membrane lipoprotein wza fold like	Outer membrane lipoprotein wza domain like	CATH (4.3.0)
C	3.30.1950.10	Alpha Beta	2-Layer Sandwich	wza like fold	wza like domain	CATH (4.3.0)
C	1.20.5.70	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
F	3.10.560.10	Alpha Beta	Roll	Outer membrane lipoprotein wza fold like	Outer membrane lipoprotein wza domain like	CATH (4.3.0)
F	3.30.1950.10	Alpha Beta	2-Layer Sandwich	wza like fold	wza like domain	CATH (4.3.0)
F	1.20.5.70	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
G	3.10.560.10	Alpha Beta	Roll	Outer membrane lipoprotein wza fold like	Outer membrane lipoprotein wza domain like	CATH (4.3.0)
G	3.30.1950.10	Alpha Beta	2-Layer Sandwich	wza like fold	wza like domain	CATH (4.3.0)
G	1.20.5.70	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
H	3.10.560.10	Alpha Beta	Roll	Outer membrane lipoprotein wza fold like	Outer membrane lipoprotein wza domain like	CATH (4.3.0)
H	3.30.1950.10	Alpha Beta	2-Layer Sandwich	wza like fold	wza like domain	CATH (4.3.0)
H	1.20.5.70	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF10531	SLBB domain (SLBB)	SLBB domain	-	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	PF22461	SLBB domain (SLBB_2)	SLBB domain	This entry represents a set of SLBB domains [5].	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	PF18412	Outer-membrane lipoprotein Wza C-terminal domain (Wza_C)	Outer-membrane lipoprotein Wza C-terminal domain	This is the C-terminal domain found in Wza, an integral outer membrane lipoprotein, which is essential for group 1 capsule export in Escherichia coli. The domain is exposed on the cell surface and is suggested to mimic antimicrobial peptide pore form ...	This is the C-terminal domain found in Wza, an integral outer membrane lipoprotein, which is essential for group 1 capsule export in Escherichia coli. The domain is exposed on the cell surface and is suggested to mimic antimicrobial peptide pore formation [1].	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	PF02563	Polysaccharide biosynthesis/export protein (Poly_export)	Polysaccharide biosynthesis/export protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	OUTER MEMBRANE LIPOPROTEIN WZA	wide pore channel activity passive transmembrane transporter activity channel activity porin activity transporter activity transmembrane transporter activity macromolecule transmembrane transporter activity polysaccharide transmembrane transporter activity carbohydrate transmembrane transporter activity	localization transport monoatomic ion transport establishment of localization	protein-containing complex cellular anatomical structure membrane pore complex membrane protein complex cell periphery cell outer membrane external encapsulating structure cell envelope outer membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR049712	Polysaccharide export protein	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR040716	Outer-membrane lipoprotein Wza, C-terminal domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR003715	Polysaccharide export protein, N-terminal domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR054765	SLBB domain	Domain