Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042533 3000526 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042528 3000503 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042531 3000526 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042523 3000503 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AACR_tran_4the2rddA11 A: alpha bundlesX: Multidrug efflux transporter AcrB transmembrane domain (From Topology)H: Multidrug efflux transporter AcrB transmembrane domain (From Topology)T: Multidrug efflux transporter AcrB transmembrane domainF: ACR_tran_4thECOD (1.6)
AACR_tran_1ste2rddA12 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_1stECOD (1.6)
AACR_tran_5the2rddA13 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_5thECOD (1.6)
AACR_tran_3rde2rddA15 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_3rdECOD (1.6)
AACR_tran_6the2rddA14 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_6thECOD (1.6)
AACR_tran_2nde2rddA7 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_2ndECOD (1.6)
AACR_tran_6th_1e2rddA9 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_6th_1ECOD (1.6)
BYajCe2rddB1 A: extended segmentsX: Preprotein translocase subunit YajC (From Topology)H: Preprotein translocase subunit YajC (From Topology)T: Preprotein translocase subunit YajCF: YajCECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

AMR Gene: CARD Annotation CARD Database Homepage

ChainsAccessionShort NameDescriptionProvenance Source (Version)
ARO:3000216acrBProtein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter.CARD (3.3.0)

AMR Gene Family: CARD Annotation CARD Database Homepage

ChainsAccessionGene FamilyDrug Class Resistance MachanismProvenance Source (Version)
ARO:0010004resistance-nodulation-cell division (RND) antibiotic efflux pumpfluoroquinolone antibiotic, cephalosporin, glycylcycline, penam, tetracycline antibiotic, rifamycin antibiotic, phenicol antibiotic, disinfecting agents and antisepticsantibiotic effluxCARD (3.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00873AcrB/AcrD/AcrF family (ACR_tran)AcrB/AcrD/AcrF family- Family
PF02699Preprotein translocase subunit (YajC)Preprotein translocase subunit- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Acriflavine resistance protein B
UPF0092 membrane protein yajC-