Annotations: 3IZK

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Cpn60_TCP1_1st	e3izkA8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
A	Cpn60_TCP1_2nd	e3izkA7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
A	Cpn60_TCP1_2nd_1	e3izkA9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
C	Cpn60_TCP1_1st	e3izkC8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
C	Cpn60_TCP1_2nd	e3izkC7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
C	Cpn60_TCP1_2nd_1	e3izkC9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
D	Cpn60_TCP1_1st	e3izkD8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
D	Cpn60_TCP1_2nd	e3izkD7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
D	Cpn60_TCP1_2nd_1	e3izkD9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
G	Cpn60_TCP1_1st	e3izkG8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
G	Cpn60_TCP1_2nd	e3izkG7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
G	Cpn60_TCP1_2nd_1	e3izkG9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
J	Cpn60_TCP1_1st	e3izkJ5	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
J	Cpn60_TCP1_2nd	e3izkJ4	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
J	Cpn60_TCP1_2nd_1	e3izkJ6	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
K	Cpn60_TCP1_1st	e3izkK8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
K	Cpn60_TCP1_2nd	e3izkK7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
K	Cpn60_TCP1_2nd_1	e3izkK9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
L	Cpn60_TCP1_1st	e3izkL8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
L	Cpn60_TCP1_2nd	e3izkL7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
L	Cpn60_TCP1_2nd_1	e3izkL9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
O	Cpn60_TCP1_1st	e3izkO8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
O	Cpn60_TCP1_2nd	e3izkO7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
O	Cpn60_TCP1_2nd_1	e3izkO9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
P	Cpn60_TCP1_1st	e3izkP8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
P	Cpn60_TCP1_2nd	e3izkP7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
P	Cpn60_TCP1_2nd_1	e3izkP9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
B	Cpn60_TCP1_1st	e3izkB8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
B	Cpn60_TCP1_2nd	e3izkB7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
B	Cpn60_TCP1_2nd_1	e3izkB9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
E	Cpn60_TCP1_1st	e3izkE8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
E	Cpn60_TCP1_2nd	e3izkE7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
E	Cpn60_TCP1_2nd_1	e3izkE9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
F	Cpn60_TCP1_1st	e3izkF8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
F	Cpn60_TCP1_2nd	e3izkF7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
F	Cpn60_TCP1_2nd_1	e3izkF9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
H	Cpn60_TCP1_1st	e3izkH8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
H	Cpn60_TCP1_2nd	e3izkH7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
H	Cpn60_TCP1_2nd_1	e3izkH9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
I	Cpn60_TCP1_1st	e3izkI8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
I	Cpn60_TCP1_2nd	e3izkI7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
I	Cpn60_TCP1_2nd_1	e3izkI9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
M	Cpn60_TCP1_1st	e3izkM8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
M	Cpn60_TCP1_2nd	e3izkM7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
M	Cpn60_TCP1_2nd_1	e3izkM9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
N	Cpn60_TCP1_1st	e3izkN8	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
N	Cpn60_TCP1_2nd	e3izkN7	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
N	Cpn60_TCP1_2nd_1	e3izkN9	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	Chaperonin	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding unfolded protein binding protein binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity ATP-dependent protein folding chaperone protein folding chaperone cation binding metal ion binding identical protein binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR054827	Thermosome subunit alpha	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR012714	Thermosome, archaeal	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR053374	TCP-1 chaperonin-containing T-complex	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR002194	Chaperonin TCP-1, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family