Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
Azf-PARPe3odaA1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: PARP-type zinc fingerF: zf-PARPECOD (1.6)
Bzf-PARPe3odaB1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: PARP-type zinc fingerF: zf-PARPECOD (1.6)
Dzf-PARPe3odaD1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: PARP-type zinc fingerF: zf-PARPECOD (1.6)
Hzf-PARPe3odaH1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: PARP-type zinc fingerF: zf-PARPECOD (1.6)
Czf-PARPe3odaC1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: PARP-type zinc fingerF: zf-PARPECOD (1.6)
Ezf-PARPe3odaE1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: PARP-type zinc fingerF: zf-PARPECOD (1.6)
Fzf-PARPe3odaF1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: PARP-type zinc fingerF: zf-PARPECOD (1.6)
Gzf-PARPe3odaG1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: PARP-type zinc fingerF: zf-PARPECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF00645Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region (zf-PARP)Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger regionPoly(ADP-ribose) polymerase is an important regulatory component of the cellular response to DNA damage. The amino-terminal region of Poly(ADP-ribose) polymerase consists of two PARP-type zinc fingers. This region acts as a DNA nick sensor.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
I, J, K, L, M
5'-D(*GP*CP*CP*TP*GP*CP*AP*GP*GP*C)-3'---
A, B, C, D, E
Poly [ADP-ribose] polymerase 1

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR038650PADR1, C-terminal domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR050800ADP-ribosyltransferase diphtheria toxin-likeFamily
A, B, C, D, E
IPR001510Zinc finger, PARP-typeDomain
A, B, C, D, E
IPR012982PARP1-like, PADR1 domain, zinc ribbon foldDomain
A, B, C, D, E
IPR049296PARP1-like, PADR1 domain, N-terminal helical subdomainDomain
A, B, C, D, E
IPR012317Poly(ADP-ribose) polymerase, catalytic domainDomain
A, B, C, D, E
IPR036957Zinc finger, PARP-type superfamilyHomologous Superfamily
A, B, C, D, E
IPR001357BRCT domainDomain
A, B, C, D, E
IPR036930WGR domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR008893WGR domainDomain
A, B, C, D, E
IPR036420BRCT domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR036616Poly(ADP-ribose) polymerase, regulatory domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR004102Poly(ADP-ribose) polymerase, regulatory domainDomain
A, B, C, D, E
IPR008288Poly [ADP-ribose] polymeraseFamily