3ODE
Human PARP-1 zinc finger 2 (Zn2) bound to DNA
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | zf-PARP | e3odeA1 | A: few secondary structure elements | X: Glucocorticoid receptor-like | H: LIM domain-like | T: PARP-type zinc finger | F: zf-PARP | ECOD (1.6) |
B | zf-PARP | e3odeB1 | A: few secondary structure elements | X: Glucocorticoid receptor-like | H: LIM domain-like | T: PARP-type zinc finger | F: zf-PARP | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.30.1740.10 | Alpha Beta | 2-Layer Sandwich | first zn-finger domain of poly(adp-ribose) polymerase-1 | Zinc finger, PARP-type | CATH (4.3.0) |
B | 3.30.1740.10 | Alpha Beta | 2-Layer Sandwich | first zn-finger domain of poly(adp-ribose) polymerase-1 | Zinc finger, PARP-type | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00645 | Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region (zf-PARP) | Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region | Poly(ADP-ribose) polymerase is an important regulatory component of the cellular response to DNA damage. The amino-terminal region of Poly(ADP-ribose) polymerase consists of two PARP-type zinc fingers. This region acts as a DNA nick sensor. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR038650 | PADR1, C-terminal domain superfamily | Homologous Superfamily | |
IPR050800 | ADP-ribosyltransferase diphtheria toxin-like | Family | |
IPR001510 | Zinc finger, PARP-type | Domain | |
IPR012982 | PARP1-like, PADR1 domain, zinc ribbon fold | Domain | |
IPR049296 | PARP1-like, PADR1 domain, N-terminal helical subdomain | Domain | |
IPR012317 | Poly(ADP-ribose) polymerase, catalytic domain | Domain | |
IPR036957 | Zinc finger, PARP-type superfamily | Homologous Superfamily | |
IPR001357 | BRCT domain | Domain | |
IPR036930 | WGR domain superfamily | Homologous Superfamily | |
IPR008893 | WGR domain | Domain | |
IPR036420 | BRCT domain superfamily | Homologous Superfamily | |
IPR036616 | Poly(ADP-ribose) polymerase, regulatory domain superfamily | Homologous Superfamily | |
IPR004102 | Poly(ADP-ribose) polymerase, regulatory domain | Domain | |
IPR008288 | Poly [ADP-ribose] polymerase | Family |