3VE2 | pdb_00003ve2

The 2.1 angstrom crystal structure of Transferrin binding protein B (TbpB) from serogroup B M982 Neisseria meningitidis

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	TbpB N-lobe and C-lobe handle domains-like	8052221	3002099	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	TbpB N-lobe and C-lobe beta-barrel domains-like	8052220	3002098	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	TbpB N-lobe and C-lobe beta-barrel domains-like	8047030	3002098	SCOP2B (2022-06-29)
A	SCOP2 Family	N-lobe and C-lobe of Tf-binding protein B-like	8047021	4006246	SCOP2 (2022-06-29)
A	SCOP2 Family	N-lobe and C-lobe of Tf-binding protein B-like	8048882	4006246	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	TbpB N-lobe and C-lobe beta-barrel domains-like	8052220	3002098	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	TbpB N-lobe and C-lobe beta-barrel domains-like	8047030	3002098	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	TbpB N-lobe and C-lobe handle domains-like	8052221	3002099	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	TbpB N-lobe and C-lobe handle domains-like	8052222	3002099	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	TbpB_A	e3ve2B3	A: beta barrels	X: Handle domain in transferrin-binding protein B (From Topology)	H: Handle domain in transferrin-binding protein B (From Topology)	T: Handle domain in transferrin-binding protein B	F: TbpB_A	ECOD (1.6)
B	TbpB_B_D	e3ve2B1	A: beta barrels	X: Outer membrane meander beta-barrels	H: OMPA-like (From Topology)	T: OMPA-like	F: TbpB_B_D	ECOD (1.6)
A	TbpB_A	e3ve2A3	A: beta barrels	X: Handle domain in transferrin-binding protein B (From Topology)	H: Handle domain in transferrin-binding protein B (From Topology)	T: Handle domain in transferrin-binding protein B	F: TbpB_A	ECOD (1.6)
A	TbpB_B_D	e3ve2A1	A: beta barrels	X: Outer membrane meander beta-barrels	H: OMPA-like (From Topology)	T: OMPA-like	F: TbpB_B_D	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.40.128.250	Mainly Beta	Beta Barrel	Lipocalin		CATH (4.3.0)
B	2.40.160.90	Mainly Beta	Beta Barrel	Porin		CATH (4.3.0)
B	2.40.128.240	Mainly Beta	Beta Barrel	Lipocalin		CATH (4.3.0)
A	2.40.128.250	Mainly Beta	Beta Barrel	Lipocalin		CATH (4.3.0)
A	2.40.160.90	Mainly Beta	Beta Barrel	Porin		CATH (4.3.0)
A	2.40.128.240	Mainly Beta	Beta Barrel	Lipocalin		CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Transferrin-binding protein 2	-	-	cell surface cellular anatomical structure cell periphery cell outer membrane external encapsulating structure membrane cell envelope outer membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR011250	Outer membrane protein/outer membrane enzyme PagP, beta-barrel	Homologous Superfamily
A, B	IPR001677	Transferrin-binding protein B, C-lobe/N-lobe beta-barrel domain	Domain
A, B	IPR035313	Transferrin-binding protein B, N-lobe handle	Domain
A, B	IPR038669	TbpB, N-lobe handle domain superfamily	Homologous Superfamily
A, B	IPR038197	TbpB, C-lobe handle domain superfamily	Homologous Superfamily
A, B	IPR035316	Transferrin-binding protein B, C-lobe handle domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.