4DVE

Crystal structure at 2.1 A of the S-component for biotin from an ECF-type ABC transporter

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Gx transporter-like	8054033	3002268	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Gx transporter-like	8054033	3002268	SCOP2B (2022-06-29)
A	SCOP2 Family	BioY-like	8050682	4006999	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Gx transporter-like	8054033	3002268	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	BioY	e4dveB1	A: alpha bundles	X: Spectrin repeat-like	H: S-component of energy-coupling factor (ECF) transporters (From Topology)	T: S-component of energy-coupling factor (ECF) transporters	F: BioY	ECOD (1.6)
C	BioY	e4dveC1	A: alpha bundles	X: Spectrin repeat-like	H: S-component of energy-coupling factor (ECF) transporters (From Topology)	T: S-component of energy-coupling factor (ECF) transporters	F: BioY	ECOD (1.6)
A	BioY	e4dveA1	A: alpha bundles	X: Spectrin repeat-like	H: S-component of energy-coupling factor (ECF) transporters (From Topology)	T: S-component of energy-coupling factor (ECF) transporters	F: BioY	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	1.10.1760.20	Mainly Alpha	Orthogonal Bundle	Arp2/3 complex 21 kDa subunit ARPC3		CATH (4.3.0)
C	1.10.1760.20	Mainly Alpha	Orthogonal Bundle	Arp2/3 complex 21 kDa subunit ARPC3		CATH (4.3.0)
A	1.10.1760.20	Mainly Alpha	Orthogonal Bundle	Arp2/3 complex 21 kDa subunit ARPC3		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF02632	BioY family (BioY)	BioY family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	Biotin transporter BioY	sulfur compound transmembrane transporter activity vitamin transmembrane transporter activity amide transmembrane transporter activity transporter activity biotin transmembrane transporter activity monocarboxylic acid transmembrane transporter activity carboxylic acid transmembrane transporter activity organic acid transmembrane transporter activity transmembrane transporter activity organic anion transmembrane transporter activity	-	cell periphery cellular anatomical structure plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR003784	BioY protein	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B, C	OPM				S component of vitamin uptake transporter

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B, C	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B, C	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B, C	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Energy-Coupling Factor (ECF) Transporters	BioY, S component of the Biotin Transporter

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.