4KWT | pdb_00004kwt

Crystal structure of unliganded anabolic ornithine carbamoyltransferase from Vibrio vulnificus at 1.86 A resolution

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4kwta1	Alpha and beta proteins (a/b)	ATC-like	Aspartate/ornithine carbamoyltransferase	automated matches	automated matches	(Vibrio vulnificus CMCP6 ) [TaxId: 216895 ],	SCOPe (2.08)
A	d4kwta3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Vibrio vulnificus CMCP6 ) [TaxId: 216895 ],	SCOPe (2.08)
B	d4kwtb1	Alpha and beta proteins (a/b)	ATC-like	Aspartate/ornithine carbamoyltransferase	automated matches	automated matches	(Vibrio vulnificus CMCP6 ) [TaxId: 216895 ],	SCOPe (2.08)
B	d4kwtb3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Vibrio vulnificus CMCP6 ) [TaxId: 216895 ],	SCOPe (2.08)
C	d4kwtc1	Alpha and beta proteins (a/b)	ATC-like	Aspartate/ornithine carbamoyltransferase	automated matches	automated matches	(Vibrio vulnificus CMCP6 ) [TaxId: 216895 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	OTCace	e4kwtA3	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: Aspartate/ornithine carbamoyltransferase	F: OTCace	ECOD (1.6)
A	OTCace_N	e4kwtA4	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: Aspartate/ornithine carbamoyltransferase	F: OTCace_N	ECOD (1.6)
B	OTCace	e4kwtB3	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: Aspartate/ornithine carbamoyltransferase	F: OTCace	ECOD (1.6)
B	OTCace_N	e4kwtB4	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: Aspartate/ornithine carbamoyltransferase	F: OTCace_N	ECOD (1.6)
C	OTCace	e4kwtC3	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: Aspartate/ornithine carbamoyltransferase	F: OTCace	ECOD (1.6)
C	OTCace_N	e4kwtC4	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: Aspartate/ornithine carbamoyltransferase	F: OTCace_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1370	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Aspartate/ornithine carbamoyltransferase	CATH (4.3.0)
B	3.40.50.1370	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Aspartate/ornithine carbamoyltransferase	CATH (4.3.0)
C	3.40.50.1370	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Aspartate/ornithine carbamoyltransferase	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	Ornithine carbamoyltransferase	binding amino acid binding carboxyl- or carbamoyltransferase activity ornithine carbamoyltransferase activity transferase activity, transferring one-carbon groups transferase activity catalytic activity	L-arginine biosynthetic process oxoacid metabolic process amino acid metabolic process organic acid metabolic process organic acid biosynthetic process alpha-amino acid metabolic process L-glutamine family amino acid biosynthetic process carboxylic acid biosynthetic process L-arginine biosynthetic process via ornithine arginine metabolic process small molecule metabolic process small molecule biosynthetic process carboxylic acid metabolic process primary metabolic process L-arginine biosynthetic process oxoacid metabolic process amino acid metabolic process organic acid metabolic process organic acid biosynthetic process alpha-amino acid metabolic process L-glutamine family amino acid biosynthetic process carboxylic acid biosynthetic process L-arginine biosynthetic process via ornithine arginine metabolic process small molecule metabolic process small molecule biosynthetic process carboxylic acid metabolic process primary metabolic process L-amino acid biosynthetic process L-amino acid metabolic process proteinogenic amino acid metabolic process amino acid biosynthetic process biosynthetic process proteinogenic amino acid biosynthetic process metabolic process cellular process alpha-amino acid biosynthetic process non-proteinogenic amino acid metabolic process citrulline biosynthetic process citrulline metabolic process non-proteinogenic amino acid biosynthetic process	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR006132	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding	Domain
A, B, C	IPR006131	Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain	Domain
A, B, C	IPR036901	Aspartate/ornithine carbamoyltransferase superfamily	Homologous Superfamily
A, B, C	IPR006130	Aspartate/ornithine carbamoyltransferase	Family
A, B, C	IPR002292	Ornithine/putrescine carbamoyltransferase	Family
A, B, C	IPR024904	Ornithine carbamoyltransferase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.