Annotations: 4U9Q

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Single hybrid motif	8092392	3001880	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Nqo1 FMN-binding domain-like	8092394	3001265	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Nqo1 middle domain-like	8092395	3000871	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Nqo1 middle domain-like	8092395	3000871	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Single hybrid motif	8092392	3001880	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Nqo1 FMN-binding domain-like	8092394	3001265	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	NQRA_SLBB	e4u9qA1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Nqo1 middle domain-like	F: NQRA_SLBB	ECOD (1.6)
A	NQRA_N	e4u9qA3	A: a+b complex topology	X: alpha/beta-Hammerhead/Barrel-sandwich hybrid	H: alpha/beta-Hammerhead/Barrel-sandwich hybrid	T: Single hybrid motif	F: NQRA_N	ECOD (1.6)
A	NQRA_C	e4u9qA2	A: a/b three-layered sandwiches	X: Nqo1 FMN-binding domain-like (From Topology)	H: Nqo1 FMN-binding domain-like (From Topology)	T: Nqo1 FMN-binding domain-like	F: NQRA_C	ECOD (1.6)
B	NQRA_SLBB	e4u9qB2	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Nqo1 middle domain-like	F: NQRA_SLBB	ECOD (1.6)
B	NQRA_N	e4u9qB1	A: a+b complex topology	X: alpha/beta-Hammerhead/Barrel-sandwich hybrid	H: alpha/beta-Hammerhead/Barrel-sandwich hybrid	T: Single hybrid motif	F: NQRA_N	ECOD (1.6)
B	NQRA_C	e4u9qB3	A: a/b three-layered sandwiches	X: Nqo1 FMN-binding domain-like (From Topology)	H: Nqo1 FMN-binding domain-like (From Topology)	T: Nqo1 FMN-binding domain-like	F: NQRA_C	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF11973	NQRA C-terminal domain (NQRA_SLBB)	NQRA C-terminal domain	This family consists of the C-terminal domain of several bacterial Na(+)-translocating NADH-quinone reductase subunit A (NQRA) proteins. The Na(+)-translocating NADH: ubiquinone oxidoreductase (Na(+)-NQR) generates an electrochemical Na(+) potential ...	This family consists of the C-terminal domain of several bacterial Na(+)-translocating NADH-quinone reductase subunit A (NQRA) proteins. The Na(+)-translocating NADH: ubiquinone oxidoreductase (Na(+)-NQR) generates an electrochemical Na(+) potential driven by aerobic respiration [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Na(+)-translocating NADH-quinone reductase subunit A	oxidoreductase activity oxidoreductase activity, acting on NAD(P)H oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor catalytic activity	localization transport monoatomic ion transport monoatomic cation transport establishment of localization sodium ion transport metal ion transport	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR022615	Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain	Domain
A, B	IPR008703	Na(+)-translocating NADH-quinone reductase subunit A	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.