5AKD | pdb_00005akd

MutS in complex with the N-terminal domain of MutL - crystal form 3

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
L	SCOP2B Superfamily	Ribosomal protein S5 domain 2-like	8034438	3000100	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GHKL (Gyrase, Hsp90, Histidine Kinase, MutL) domain-like	8036209	3000091	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GHKL (Gyrase, Hsp90, Histidine Kinase, MutL) domain-like	8036209	3000091	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Ribosomal protein S5 domain 2-like	8034438	3000100	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GHKL (Gyrase, Hsp90, Histidine Kinase, MutL) domain-like	8036209	3000091	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Ribosomal protein S5 domain 2-like	8034438	3000100	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Ribosomal protein S5 domain 2-like	8034438	3000100	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GHKL (Gyrase, Hsp90, Histidine Kinase, MutL) domain-like	8036209	3000091	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GHKL (Gyrase, Hsp90, Histidine Kinase, MutL) domain-like	8036209	3000091	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Ribosomal protein S5 domain 2-like	8034438	3000100	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GHKL (Gyrase, Hsp90, Histidine Kinase, MutL) domain-like	8036209	3000091	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Ribosomal protein S5 domain 2-like	8034438	3000100	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	MutS domain III-like	8056694	3001131	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	ABC transporter-like P-loop ATPases	8056695	3002020	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	MutS domain II-like	8056693	3000587	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	ABC transporter-like P-loop ATPases	8056695	3002020	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	MutS domain II-like	8056693	3000587	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	MutS domain III-like	8056694	3001131	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	ABC transporter-like P-loop ATPases	8056695	3002020	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	MutS domain II-like	8056693	3000587	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	MutS domain III-like	8056694	3001131	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	ABC transporter-like P-loop ATPases	8056695	3002020	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	MutS domain III-like	8056694	3001131	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	MutS domain II-like	8056693	3000587	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ABC transporter-like P-loop ATPases	8056695	3002020	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	MutS domain II-like	8056693	3000587	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	MutS domain III-like	8056694	3001131	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	MutS domain II-like	8056693	3000587	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	ABC transporter-like P-loop ATPases	8056695	3002020	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	MutS domain III-like	8056694	3001131	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
L	DNA_mis_repair	e5akdL2	A: a+b two layers	X: Ribosomal protein S5 domain 2-like (From Topology)	H: Ribosomal protein S5 domain 2-like (From Topology)	T: Ribosomal protein S5 domain 2-like	F: DNA_mis_repair	ECOD (1.6)
L	HATPase_c_3	e5akdL1	A: a+b two layers	X: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	H: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology)	T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	F: HATPase_c_3	ECOD (1.6)
K	DNA_mis_repair	e5akdK2	A: a+b two layers	X: Ribosomal protein S5 domain 2-like (From Topology)	H: Ribosomal protein S5 domain 2-like (From Topology)	T: Ribosomal protein S5 domain 2-like	F: DNA_mis_repair	ECOD (1.6)
K	HATPase_c_3	e5akdK1	A: a+b two layers	X: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	H: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology)	T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	F: HATPase_c_3	ECOD (1.6)
H	DNA_mis_repair	e5akdH1	A: a+b two layers	X: Ribosomal protein S5 domain 2-like (From Topology)	H: Ribosomal protein S5 domain 2-like (From Topology)	T: Ribosomal protein S5 domain 2-like	F: DNA_mis_repair	ECOD (1.6)
H	HATPase_c_3	e5akdH2	A: a+b two layers	X: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	H: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology)	T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	F: HATPase_c_3	ECOD (1.6)
G	DNA_mis_repair	e5akdG1	A: a+b two layers	X: Ribosomal protein S5 domain 2-like (From Topology)	H: Ribosomal protein S5 domain 2-like (From Topology)	T: Ribosomal protein S5 domain 2-like	F: DNA_mis_repair	ECOD (1.6)
G	HATPase_c_3	e5akdG2	A: a+b two layers	X: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	H: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology)	T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	F: HATPase_c_3	ECOD (1.6)
D	DNA_mis_repair	e5akdD1	A: a+b two layers	X: Ribosomal protein S5 domain 2-like (From Topology)	H: Ribosomal protein S5 domain 2-like (From Topology)	T: Ribosomal protein S5 domain 2-like	F: DNA_mis_repair	ECOD (1.6)
D	HATPase_c_3	e5akdD2	A: a+b two layers	X: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	H: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology)	T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	F: HATPase_c_3	ECOD (1.6)
C	DNA_mis_repair	e5akdC1	A: a+b two layers	X: Ribosomal protein S5 domain 2-like (From Topology)	H: Ribosomal protein S5 domain 2-like (From Topology)	T: Ribosomal protein S5 domain 2-like	F: DNA_mis_repair	ECOD (1.6)
C	HATPase_c_3	e5akdC2	A: a+b two layers	X: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	H: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology)	T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	F: HATPase_c_3	ECOD (1.6)
J	MutS_III	e5akdJ1	A: alpha bundles	X: Four-helical up-and-down bundle	H: DNA repair protein MutS, domain III (From Topology)	T: DNA repair protein MutS, domain III	F: MutS_III	ECOD (1.6)
J	MutS_V	e5akdJ2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: MutS_V	ECOD (1.6)
J	MutS_II	e5akdJ3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: MutS_II	ECOD (1.6)
I	MutS_III	e5akdI1	A: alpha bundles	X: Four-helical up-and-down bundle	H: DNA repair protein MutS, domain III (From Topology)	T: DNA repair protein MutS, domain III	F: MutS_III	ECOD (1.6)
I	MutS_V	e5akdI2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: MutS_V	ECOD (1.6)
I	MutS_II	e5akdI3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: MutS_II	ECOD (1.6)
F	MutS_III	e5akdF1	A: alpha bundles	X: Four-helical up-and-down bundle	H: DNA repair protein MutS, domain III (From Topology)	T: DNA repair protein MutS, domain III	F: MutS_III	ECOD (1.6)
F	MutS_V	e5akdF2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: MutS_V	ECOD (1.6)
F	MutS_II	e5akdF3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: MutS_II	ECOD (1.6)
E	MutS_III	e5akdE1	A: alpha bundles	X: Four-helical up-and-down bundle	H: DNA repair protein MutS, domain III (From Topology)	T: DNA repair protein MutS, domain III	F: MutS_III	ECOD (1.6)
E	MutS_V	e5akdE2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: MutS_V	ECOD (1.6)
E	MutS_II	e5akdE3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: MutS_II	ECOD (1.6)
B	MutS_III	e5akdB1	A: alpha bundles	X: Four-helical up-and-down bundle	H: DNA repair protein MutS, domain III (From Topology)	T: DNA repair protein MutS, domain III	F: MutS_III	ECOD (1.6)
B	MutS_V	e5akdB2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: MutS_V	ECOD (1.6)
B	MutS_II	e5akdB3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: MutS_II	ECOD (1.6)
A	MutS_III	e5akdA1	A: alpha bundles	X: Four-helical up-and-down bundle	H: DNA repair protein MutS, domain III (From Topology)	T: DNA repair protein MutS, domain III	F: MutS_III	ECOD (1.6)
A	MutS_V	e5akdA2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: MutS_V	ECOD (1.6)
A	MutS_II	e5akdA3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: MutS_II	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C, D, G, H, K C, D, G, H, K, L	PF01119	DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)	DNA mismatch repair protein, C-terminal domain	-	Family
C, D, G, H, K C, D, G, H, K, L	PF13589	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.	Domain
A, B, E, F, I A, B, E, F, I, J	PF05188	MutS domain II (MutS_II)	MutS domain II	This domain is found in proteins of the MutS family (DNA mismatch repair proteins) and is found associated with Pfam:PF00488, Pfam:PF01624, Pfam:PF05192 and Pfam:PF05190. The MutS family of proteins is named after the Salmonella typhimurium MutS prot ...	This domain is found in proteins of the MutS family (DNA mismatch repair proteins) and is found associated with Pfam:PF00488, Pfam:PF01624, Pfam:PF05192 and Pfam:PF05190. The MutS family of proteins is named after the Salmonella typhimurium MutS protein involved in mismatch repair; other members of the family included the eukaryotic MSH 1,2,3, 4,5 and 6 proteins. These have various roles in DNA repair and recombination. Human MSH has been implicated in non-polyposis colorectal carcinoma (HNPCC) and is a mismatch binding protein [2]. This domain corresponds to domain II in Thermus aquaticus MutS as characterised in [4], and has similarity resembles RNAse-H-like domains (see Pfam:PF00075).	Domain
A, B, E, F, I A, B, E, F, I, J	PF05192	MutS domain III (MutS_III)	MutS domain III	This domain is found in proteins of the MutS family (DNA mismatch repair proteins) and is found associated with Pfam:PF00488, Pfam:PF05188, Pfam:PF01624 and Pfam:PF05190. The MutS family of proteins is named after the Salmonella typhimurium MutS prot ...	This domain is found in proteins of the MutS family (DNA mismatch repair proteins) and is found associated with Pfam:PF00488, Pfam:PF05188, Pfam:PF01624 and Pfam:PF05190. The MutS family of proteins is named after the Salmonella typhimurium MutS protein involved in mismatch repair; other members of the family included the eukaryotic MSH 1,2,3, 4,5 and 6 proteins. These have various roles in DNA repair and recombination. Human MSH has been implicated in non-polyposis colorectal carcinoma (HNPCC) and is a mismatch binding protein [2]. The aligned region corresponds with domain III, which is central to the structure of Thermus aquaticus MutS as characterised in [4].	Domain
A, B, E, F, I A, B, E, F, I, J	PF00488	MutS domain V (MutS_V)	MutS domain V	This domain is found in proteins of the MutS family (DNA mismatch repair proteins) and is found associated with Pfam:PF01624, Pfam:PF05188, Pfam:PF05192 and Pfam:PF05190. The mutS family of proteins is named after the Salmonella typhimurium MutS prot ...	This domain is found in proteins of the MutS family (DNA mismatch repair proteins) and is found associated with Pfam:PF01624, Pfam:PF05188, Pfam:PF05192 and Pfam:PF05190. The mutS family of proteins is named after the Salmonella typhimurium MutS protein involved in mismatch repair; other members of the family included the eukaryotic MSH 1,2,3, 4,5 and 6 proteins. These have various roles in DNA repair and recombination. Human MSH has been implicated in non-polyposis colorectal carcinoma (HNPCC) and is a mismatch binding protein [2]. The aligned region corresponds with domain V of Thermus aquaticus MutS as characterised in [4], which contains a Walker A motif, and is structurally similar to the ATPase domain of ABC transporters.	Domain
A, B, E, F, I A, B, E, F, I, J	PF05190	MutS family domain IV (MutS_IV)	MutS family domain IV	This domain is found in proteins of the MutS family (DNA mismatch repair proteins) and is found associated with Pfam:PF01624, Pfam:PF05188, Pfam:PF05192 and Pfam:PF00488. The mutS family of proteins is named after the Salmonella typhimurium MutS prot ...	This domain is found in proteins of the MutS family (DNA mismatch repair proteins) and is found associated with Pfam:PF01624, Pfam:PF05188, Pfam:PF05192 and Pfam:PF00488. The mutS family of proteins is named after the Salmonella typhimurium MutS protein involved in mismatch repair; other members of the family included the eukaryotic MSH 1,2,3, 4,5 and 6 proteins. These have various roles in DNA repair and recombination. Human MSH has been implicated in non-polyposis colorectal carcinoma (HNPCC) and is a mismatch binding protein [2]. The aligned region corresponds in part with globular domain IV, which is involved in DNA binding, in Thermus aquaticus MutS as characterised in [4].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
C, D, G, H, K C, D, G, H, K, L	DNA MISMATCH REPAIR PROTEIN MUTL	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding DNA binding nucleic acid binding double-stranded DNA binding mismatched DNA binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity identical protein binding protein binding ATP-dependent activity, acting on DNA DNA damage sensor activity molecular sensor activity catalytic activity, acting on DNA ATP-dependent DNA damage sensor activity catalytic activity, acting on a nucleic acid molecular function regulator activity	cellular response to stimulus mismatch repair DNA-templated DNA replication response to stimulus DNA-templated DNA replication maintenance of fidelity primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication DNA replication cellular response to stress DNA damage response response to stress cellular response to stimulus mismatch repair DNA-templated DNA replication response to stimulus DNA-templated DNA replication maintenance of fidelity primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication DNA replication cellular response to stress DNA damage response response to stress metabolic process cellular process macromolecule metabolic process DNA repair regulation of DNA recombination regulation of biological process regulation of cellular process DNA recombination biological regulation regulation of macromolecule metabolic process regulation of primary metabolic process regulation of nucleobase-containing compound metabolic process regulation of metabolic process regulation of DNA metabolic process	protein-containing complex catalytic complex DNA helicase complex single-stranded DNA-dependent ATP-dependent DNA helicase complex intracellular anatomical structure cellular anatomical structure mismatch repair complex
A, B, E, F, I A, B, E, F, I, J	DNA MISMATCH REPAIR PROTEIN MUTS	DNA binding adenine/cytosine mispair binding double-stranded DNA binding binding mismatched DNA binding nucleic acid binding damaged DNA binding ATP-dependent activity, acting on DNA DNA damage sensor activity molecular sensor activity catalytic activity, acting on DNA ATP-dependent DNA damage sensor activity catalytic activity, acting on a nucleic acid molecular function regulator activity DNA binding adenine/cytosine mispair binding double-stranded DNA binding binding mismatched DNA binding nucleic acid binding damaged DNA binding ATP-dependent activity, acting on DNA DNA damage sensor activity molecular sensor activity catalytic activity, acting on DNA ATP-dependent DNA damage sensor activity catalytic activity, acting on a nucleic acid molecular function regulator activity catalytic activity ATP-dependent activity adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding ADP binding DNA binding, bending pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides identical protein binding protein binding	cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process regulation of DNA recombination regulation of biological process regulation of cellular process DNA recombination biological regulation primary metabolic process DNA metabolic process regulation of macromolecule metabolic process cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process regulation of DNA recombination regulation of biological process regulation of cellular process DNA recombination biological regulation primary metabolic process DNA metabolic process regulation of macromolecule metabolic process nucleic acid metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process metabolic process macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of metabolic process regulation of DNA metabolic process mismatch repair DNA repair	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol protein-containing complex catalytic complex MutS complex mismatch repair complex DNA repair complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C, D, G, H, K C, D, G, H, K, L	IPR038973	DNA mismatch repair protein MutL/Mlh/Pms-like	Family
C, D, G, H, K C, D, G, H, K, L	IPR037198	MutL, C-terminal domain superfamily	Homologous Superfamily
C, D, G, H, K C, D, G, H, K, L	IPR013507	DNA mismatch repair protein, S5 domain 2-like	Domain
C, D, G, H, K C, D, G, H, K, L	IPR014790	MutL, C-terminal, dimerisation	Domain
C, D, G, H, K C, D, G, H, K, L	IPR002099	DNA mismatch repair protein MutL/Mlh/PMS	Family
C, D, G, H, K C, D, G, H, K, L	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	Homologous Superfamily
C, D, G, H, K C, D, G, H, K, L	IPR042121	MutL, C-terminal domain, regulatory subdomain	Homologous Superfamily
C, D, G, H, K C, D, G, H, K, L	IPR042120	MutL, C-terminal domain, dimerisation subdomain	Homologous Superfamily
C, D, G, H, K C, D, G, H, K, L	IPR014762	DNA mismatch repair, conserved site	Conserved Site
C, D, G, H, K C, D, G, H, K, L	IPR020667	DNA mismatch repair protein, MutL	Family
C, D, G, H, K C, D, G, H, K, L	IPR020568	Ribosomal protein uS5 domain 2-type superfamily	Homologous Superfamily
C, D, G, H, K C, D, G, H, K, L	IPR014721	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	Homologous Superfamily
A, B, E, F, I A, B, E, F, I, J	IPR045076	DNA mismatch repair MutS	Family
A, B, E, F, I A, B, E, F, I, J	IPR005748	DNA mismatch repair protein MutS	Family
A, B, E, F, I A, B, E, F, I, J	IPR007861	DNA mismatch repair protein MutS, clamp	Domain
A, B, E, F, I A, B, E, F, I, J	IPR017261	DNA mismatch repair protein MutS/MSH	Family
A, B, E, F, I A, B, E, F, I, J	IPR016151	DNA mismatch repair protein MutS, N-terminal	Homologous Superfamily
A, B, E, F, I A, B, E, F, I, J	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
A, B, E, F, I A, B, E, F, I, J	IPR000432	DNA mismatch repair protein MutS, C-terminal	Domain
A, B, E, F, I A, B, E, F, I, J	IPR007696	DNA mismatch repair protein MutS, core	Domain
A, B, E, F, I A, B, E, F, I, J	IPR007860	DNA mismatch repair protein MutS, connector domain	Domain
A, B, E, F, I A, B, E, F, I, J	IPR007695	DNA mismatch repair protein MutS-like, N-terminal	Domain
A, B, E, F, I A, B, E, F, I, J	IPR036187	DNA mismatch repair protein MutS, core domain superfamily	Homologous Superfamily
A, B, E, F, I A, B, E, F, I, J	IPR036678	MutS, connector domain superfamily	Homologous Superfamily