5GHL | pdb_00005ghl

Crystal structure Analysis of the starch-binding domain of glucoamylase from Aspergillus niger

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
D	d5ghld_	All beta proteins	Prealbumin-like	Starch-binding domain-like	Starch-binding domain	Glucoamylase, granular starch-binding domain	(Aspergillus niger ) [TaxId: 5061 ],	SCOPe (2.08)
C	d5ghlc_	All beta proteins	Prealbumin-like	Starch-binding domain-like	Starch-binding domain	Glucoamylase, granular starch-binding domain	(Aspergillus niger ) [TaxId: 5061 ],	SCOPe (2.08)
B	d5ghlb_	All beta proteins	Prealbumin-like	Starch-binding domain-like	Starch-binding domain	Glucoamylase, granular starch-binding domain	(Aspergillus niger ) [TaxId: 5061 ],	SCOPe (2.08)
A	d5ghla_	All beta proteins	Prealbumin-like	Starch-binding domain-like	Starch-binding domain	Glucoamylase, granular starch-binding domain	(Aspergillus niger ) [TaxId: 5061 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
D	SCOP2B Superfamily	Starch-binding domain-like	8040280	3000816	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Starch-binding domain-like	8040280	3000816	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Starch-binding domain-like	8040280	3000816	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Starch-binding domain-like	8040280	3000816	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
D	CBM_20	e5ghlD1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Prealbumin-like	F: CBM_20	ECOD (1.6)
C	CBM_20	e5ghlC1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Prealbumin-like	F: CBM_20	ECOD (1.6)
B	CBM_20	e5ghlB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Prealbumin-like	F: CBM_20	ECOD (1.6)
A	CBM_20	e5ghlA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Prealbumin-like	F: CBM_20	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
D	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
C	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
B	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
A	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00686	Starch binding domain (CBM_20)	Starch binding domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Glucoamylase	starch binding binding polysaccharide binding carbohydrate binding alpha-glucosidase activity hydrolase activity, acting on glycosyl bonds glucosidase activity hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity catalytic activity glucan 1,4-alpha-glucosidase activity	carbohydrate metabolic process polysaccharide metabolic process metabolic process cellular process primary metabolic process macromolecule metabolic process catabolic process polysaccharide catabolic process carbohydrate catabolic process macromolecule catabolic process	membrane-bounded organelle storage vacuole intracellular anatomical structure lytic vacuole vacuole intracellular membrane-bounded organelle fungal-type vacuole intracellular organelle cellular anatomical structure organelle cytoplasm endoplasmic reticulum endomembrane system

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR013784	Carbohydrate-binding-like fold	Homologous Superfamily
A, B, C, D	IPR000165	Glucoamylase	Family
A, B, C, D	IPR008928	Six-hairpin glycosidase superfamily	Homologous Superfamily
A, B, C, D	IPR002044	Carbohydrate binding module family 20	Domain
A, B, C, D	IPR012341	Six-hairpin glycosidase-like superfamily	Homologous Superfamily
A, B, C, D	IPR008291	Glucoamylase, starch-binding	Family
A, B, C, D	IPR046966	Glucoamylase, active site	Conserved Site
A, B, C, D	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
A, B, C, D	IPR011613	GH15-like domain	Domain
A, B, C, D	IPR034836	Glucoamylase, CBM20 domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.