Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth B]GP41_1ste6ch9B1 A: a+b duplicates or obligate multimersX: MPER trimer (From Topology)H: MPER trimer (From Topology)T: MPER trimerF: GP41_1stECOD (1.6)
B [auth D]V-set_8e6ch9D1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_8ECOD (1.6)
B [auth D]C1-set_1e6ch9D2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
C [auth E]C1-sete6ch9E1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-setECOD (1.6)
C [auth E]V-set_3e6ch9E2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
D [auth G]GP120_2nde6ch9G3 A: beta barrelsX: V1/V2 domain in HIV gp120 (From Topology)H: V1/V2 domain in HIV gp120 (From Topology)T: V1/V2 domain in HIV gp120F: GP120_2ndECOD (1.6)
D [auth G]GP120_3rde6ch9G2 A: a+b two layersX: Ribosomal protein L31e-likeH: Ribosomal protein L31e/gp120 outer domain (From Topology)T: Ribosomal protein L31e/gp120 outer domainF: GP120_3rdECOD (1.6)
D [auth G]GP120_1ste6ch9G1 A: a+b two layersX: gp120 inner domain (From Topology)H: gp120 inner domain (From Topology)T: gp120 inner domainF: GP120_1stECOD (1.6)
E [auth Q]V-set_8e6ch9Q1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_8ECOD (1.6)
E [auth Q]C1-set_1e6ch9Q2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
F [auth R]C1-sete6ch9R2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-setECOD (1.6)
F [auth R]V-set_3e6ch9R1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
B [auth D]Fab 35O22, broadly neutralizing VH-CH1 Homo sapiens (human) IGHV1-18*01, IGHV1-18*04, IGHJ1*01, IGHJ4*01, IGHJ5*02, IGHJ4*02, IGHJ4*03, IGHG1*03, IGHG1*08, IGHG1*06 V-DOMAIN VH, C-DOMAIN CH1 IG FAB-GAMMA-1_LAMBDA IMGT (202449-0)
C [auth E]Fab 35O22, broadly neutralizing L-LAMBDA Homo sapiens (human) IGLV2-14*02, IGLV2-18*02, IGLV2-23*01, IGLV2-23*02, IGLV2-23*03, IGLJ1*01, IGLC2*01, IGLC2*02, IGLC3*04 V-DOMAIN V-LAMBDA, C-DOMAIN C-LAMBDA IG FAB-GAMMA-1_LAMBDA IMGT (202449-0)
E [auth Q]Fab BG18, broadly neutralizing VH-CH1 Homo sapiens (human) IGHV4-59*01, IGHV4-59*02, IGHV4-59*08, IGHJ3*01, IGHG1*03, IGHG1*08, IGHG1*06 V-DOMAIN VH, C-DOMAIN CH1 IG FAB-GAMMA-1_LAMBDA IMGT (202449-0)
F [auth R]Fab BG18, broadly neutralizing L-LAMBDA Homo sapiens (human) IGLV3-25*02, IGLJ2*01, IGLJ3*02, IGLJ3*01, IGLC3*03 V-DOMAIN V-LAMBDA, C-DOMAIN C-LAMBDA IG FAB-GAMMA-1_LAMBDA IMGT (202449-0)

SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
F [auth R]Light ChainIGLV3 Lambdaenvelope glycoprotein gp120SAbDab (2024-12-13)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth B]PF00517Retroviral envelope protein (GP41)Retroviral envelope protein- Family
D [auth G]PF00516Envelope glycoprotein GP120 (GP120)Envelope glycoprotein GP120- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth B]Envelope glycoprotein gp41
B [auth D]35O22 Heavy Chain---
C [auth E]35O22 Light Chain---
D [auth G]Envelope glycoprotein gp120
E [auth Q]BG18 Heavy Chain---
F [auth R]BG18 Light Chain---