6EBX | pdb_00006ebx

STRUCTURE DETERMINATION OF A DIMERIC FORM OF ERABUTOXIN B, CRYSTALLIZED FROM THIOCYANATE SOLUTION

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6ebxa_	Small proteins	Snake toxin-like	Snake toxin-like	Snake venom toxins	Erabutoxin B (also neurotoxin B)	broad-banded blue sea krait (Laticauda semifasciata ) [TaxId: 8631 ],	SCOPe (2.08)
B	d6ebxb_	Small proteins	Snake toxin-like	Snake toxin-like	Snake venom toxins	Erabutoxin B (also neurotoxin B)	broad-banded blue sea krait (Laticauda semifasciata ) [TaxId: 8631 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Snake toxin-like	8038406	3000545	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Snake toxin-like	8038406	3000545	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Toxin_TOLIP	e6ebxA1	A: few secondary structure elements	X: Snake toxin-like (From Topology)	H: Snake toxin-like (From Topology)	T: Snake toxin-like	F: Toxin_TOLIP	ECOD (1.6)
B	Toxin_TOLIP	e6ebxB1	A: few secondary structure elements	X: Snake toxin-like (From Topology)	H: Snake toxin-like (From Topology)	T: Snake toxin-like	F: Toxin_TOLIP	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.10.60.10	Mainly Beta	Ribbon	CD59	CD59	CATH (4.3.0)
B	2.10.60.10	Mainly Beta	Ribbon	CD59	CD59	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF21947	Snake toxin cobra-type (Toxin_cobra-type)	Snake toxin cobra-type	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	ERABUTOXIN B	channel regulator activity ion channel regulator activity molecular function regulator activity transporter regulator activity neurotransmitter receptor regulator activity acetylcholine receptor regulator activity molecular function inhibitor activity acetylcholine receptor inhibitor activity signaling receptor inhibitor activity signaling receptor regulator activity toxin activity	-	cellular anatomical structure extracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR018354	Snake toxin, conserved site	Conserved Site
A, B	IPR045860	Snake toxin-like superfamily	Homologous Superfamily
A, B	IPR054131	Snake toxin cobra-type	Family
A, B	IPR003571	Snake three-finger toxin	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.