6NAU | pdb_00006nau

1.55 Angstrom Resolution Crystal Structure of 6-phosphogluconolactonase from Klebsiella pneumoniae

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2B Superfamily	Putative isomerase YbhE	8097138	3000175	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Putative isomerase YbhE	8097138	3000175	SCOP2B (2022-06-29)
A	SCOP2 Family	Putative isomerase YbhE	8097137	4000933	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Putative isomerase YbhE	8097138	3000175	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C	Lactonase	e6nauC1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: Lactonase	ECOD (1.6)
B	Lactonase	e6nauB1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: Lactonase	ECOD (1.6)
A	Lactonase	e6nauA1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: Lactonase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C	2.130.10.10	Mainly Beta	7 Propeller	Methylamine Dehydrogenase	Chain H	CATH (4.3.0)
B	2.130.10.10	Mainly Beta	7 Propeller	Methylamine Dehydrogenase	Chain H	CATH (4.3.0)
A	2.130.10.10	Mainly Beta	7 Propeller	Methylamine Dehydrogenase	Chain H	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	6-phosphogluconolactonase	hydrolase activity, acting on ester bonds 6-phosphogluconolactonase activity carboxylic ester hydrolase activity hydrolase activity catalytic activity	nucleoside phosphate metabolic process nicotinamide nucleotide metabolic process carbohydrate derivative metabolic process pentose-phosphate shunt, oxidative branch primary metabolic process generation of precursor metabolites and energy glucose 6-phosphate metabolic process nucleotide metabolic process NADP+ metabolic process purine-containing compound metabolic process nucleobase-containing compound metabolic process NADPH regeneration purine nucleotide metabolic process organophosphate metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate metabolic process nicotinamide nucleotide metabolic process carbohydrate derivative metabolic process pentose-phosphate shunt, oxidative branch primary metabolic process generation of precursor metabolites and energy glucose 6-phosphate metabolic process nucleotide metabolic process NADP+ metabolic process purine-containing compound metabolic process nucleobase-containing compound metabolic process NADPH regeneration purine nucleotide metabolic process organophosphate metabolic process nucleobase-containing small molecule metabolic process pentose-phosphate shunt phosphate-containing compound metabolic process pyridine-containing compound metabolic process metabolic process cellular process small molecule metabolic process phosphorus metabolic process monosaccharide metabolic process carbohydrate metabolic process hexose metabolic process glucose metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR022528	6-phosphogluconolactonase, YbhE-like	Family
A, B, C	IPR011045	Nitrous oxide reductase, N-terminal	Homologous Superfamily
A, B, C	IPR050282	Cycloisomerase 2	Family
A, B, C	IPR019405	Lactonase, 7-bladed beta-propeller	Family
A, B, C	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.