7Q4J

A thermostable lipase from Thermoanaerobacter thermohydrosulfuricus in complex a monoacylglycerol intermediate

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e7q4jA1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: F_UNCLASSIFIED	ECOD (1.6)
B	F_UNCLASSIFIED	e7q4jB1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: F_UNCLASSIFIED	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF12146	Serine aminopeptidase, S33 (Hydrolase_4)	Serine aminopeptidase, S33	-	Family
B	PF12146	Serine aminopeptidase, S33 (Hydrolase_4)	Serine aminopeptidase, S33	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Serine aminopeptidase S33 domain-containing protein	hydrolase activity, acting on ester bonds carboxylic ester hydrolase activity hydrolase activity catalytic activity	-	-
B	Serine aminopeptidase S33 domain-containing protein	hydrolase activity, acting on ester bonds carboxylic ester hydrolase activity hydrolase activity catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR053145	AB hydrolase superfamily Esterase 10	Family
A	IPR022742	Serine aminopeptidase, S33	Domain
A	IPR029058	Alpha/Beta hydrolase fold	Homologous Superfamily
B	IPR053145	AB hydrolase superfamily Esterase 10	Family
B	IPR022742	Serine aminopeptidase, S33	Domain
B	IPR029058	Alpha/Beta hydrolase fold	Homologous Superfamily

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A	MLY	Parent Component: LYS RESID: AA0075 PSI-MOD : N6,N6-dimethyl-L-lysine MOD:00084
A	MLZ	Parent Component: LYS RESID: AA0075 , AA0076 PSI-MOD : N6,N6-dimethyl-L-lysine MOD:00084 , N6-methyl-L-lysine MOD:00085
A	MSE	Parent Component: MET RESID: AA0075 , AA0076
B	MLY	Parent Component: LYS RESID: AA0075 , AA0076 , AA0075 PSI-MOD : N6,N6-dimethyl-L-lysine MOD:00084 , N6-methyl-L-lysine MOD:00085 , N6,N6-dimethyl-L-lysine MOD:00084
B	MLZ	Parent Component: LYS RESID: AA0075 , AA0076 , AA0075 , AA0076 PSI-MOD : N6,N6-dimethyl-L-lysine MOD:00084 , N6-methyl-L-lysine MOD:00085 , N6,N6-dimethyl-L-lysine MOD:00084 , N6-methyl-L-lysine MOD:00085
B	MSE	Parent Component: MET RESID: AA0075 , AA0076 , AA0075 , AA0076

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.