Annotations: 7SA8

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Alginate_lyase	e7sa8A1	A: alpha superhelices	X: Repetitive alpha hairpins	H: alpha/alpha toroid (From Topology)	T: alpha/alpha toroid	F: Alginate_lyase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.50.10.100	Mainly Alpha	Alpha/alpha barrel	Glycosyltransferase	Chondroitin AC/alginate lyase	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF05426	Alginate lyase (Alginate_lyase)	Alginate lyase	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Alginate lyase	threonine deaminase activity lyase activity ammonia-lyase activity catalytic activity carbon-nitrogen lyase activity poly(beta-D-mannuronate) lyase activity carbon-oxygen lyase activity, acting on polysaccharides carbon-oxygen lyase activity	carbohydrate metabolic process alginic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process polysaccharide biosynthetic process carbohydrate biosynthetic process carboxylic acid metabolic process primary metabolic process organic acid biosynthetic process organic acid metabolic process macromolecule biosynthetic process carboxylic acid biosynthetic process polysaccharide metabolic process biosynthetic process carbohydrate metabolic process alginic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process polysaccharide biosynthetic process carbohydrate biosynthetic process carboxylic acid metabolic process primary metabolic process organic acid biosynthetic process organic acid metabolic process macromolecule biosynthetic process carboxylic acid biosynthetic process polysaccharide metabolic process biosynthetic process small molecule metabolic process metabolic process cellular process macromolecule metabolic process alginic acid catabolic process catabolic process carbohydrate catabolic process organic acid catabolic process macromolecule catabolic process carboxylic acid catabolic process polysaccharide catabolic process small molecule catabolic process	cellular anatomical structure periplasmic space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR022859	Alginate lyase	Family
A	IPR008397	Alginate lyase domain	Domain
A	IPR008929	Chondroitin AC/alginate lyase	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.