Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 1
External Resource: Annotation
Protein Family Annotation Pfam Database Homepage
| Chains | Accession | Name | Description | Comments | Source |
|---|---|---|---|---|---|
| A, E [auth F], I [auth J], M [auth N] | PF13676 | TIR domain (TIR_2) | TIR domain | This is a family of Toll-like receptors. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
| Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
|---|---|---|---|---|
| D, H [auth I], L [auth M], P [auth Q] | target ssDNA | - | - | - |
| C, G [auth H], K [auth L], O [auth P] | guide RNA | - | - | - |
| B, F [auth G], J [auth K], N [auth O] | Piwi domain-containing protein | - | - | |
| A, E [auth F], I [auth J], M [auth N] | TIR domain-containing protein | - | - |
InterPro: Protein Family Classification InterPro Database Homepage
| Chains | Accession | Name | Type |
|---|---|---|---|
| B, F [auth G], J [auth K], N [auth O] | IPR036397 | Ribonuclease H superfamily | Homologous Superfamily |
| B, F [auth G], J [auth K], N [auth O] | IPR012337 | Ribonuclease H-like superfamily | Homologous Superfamily |
| A, E [auth F], I [auth J], M [auth N] | IPR000157 | Toll/interleukin-1 receptor homology (TIR) domain | Domain |
| A, E [auth F], I [auth J], M [auth N] | IPR035897 | Toll/interleukin-1 receptor homology (TIR) domain superfamily | Homologous Superfamily |














