This domain is found in ornithine halogenase HalD and related proteins including L-lysine 4-chlorinase BesD and L-lysine 5-chlorinase HalB. In addition to ornithine, HalD chlorinates lysine but with slower rate. This preference of HalD for ornithine ...
This domain is found in ornithine halogenase HalD and related proteins including L-lysine 4-chlorinase BesD and L-lysine 5-chlorinase HalB. In addition to ornithine, HalD chlorinates lysine but with slower rate. This preference of HalD for ornithine is due to a narrower active site pocket [1]. These enzymes are structurally very similar and adopt a typical cupin-like fold.
