A1JPY

Rentiapril

Created:	2025-09-25
Last modified:	2026-02-18

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Chemical Details
Formal Charge	0
Atom Count	35
Chiral Atom Count	2
Bond Count	36
Aromatic Bond Count	6

2D diagram of A1JPY

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Chemical Component Summary
Name	Rentiapril
Synonyms	(2~{R},4~{R})-2-(2-hydroxyphenyl)-3-(3-sulfanylpropanoyl)-1,3-thiazolidine-4-carboxylic acid
Systematic Name (OpenEye OEToolkits)	(2~{R},4~{R})-2-(2-hydroxyphenyl)-3-(3-sulfanylpropanoyl)-1,3-thiazolidine-4-carboxylic acid
Formula	C₁₃ H₁₅ N O₄ S₂
Molecular Weight	313.393
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	CACTVS	3.385	OC(=O)[CH]1CS[CH](N1C(=O)CCS)c2ccccc2O
SMILES	OpenEye OEToolkits	2.0.7	c1ccc(c(c1)C2N(C(CS2)C(=O)O)C(=O)CCS)O
Canonical SMILES	CACTVS	3.385	OC(=O)[C@@H]1CS[C@@H](N1C(=O)CCS)c2ccccc2O
Canonical SMILES	OpenEye OEToolkits	2.0.7	c1ccc(c(c1)[C@@H]2N([C@@H](CS2)C(=O)O)C(=O)CCS)O
InChI	InChI	1.06	InChI=1S/C13H15NO4S2/c15-10-4-2-1-3-8(10)12-14(11(16)5-6-19)9(7-20-12)13(17)18/h1-4,9,12,15,19H,5-7H2,(H,17,18)/t9-,12+/m0/s1
InChIKey	InChI	1.06	BSHDUMDXSRLRBI-JOYOIKCWSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB20567
Name	Rentiapril
Groups	experimental
Description	Rentiapril is a small molecule drug. The usage of the INN stem '-pril' in the name indicates that Rentiapril is a angiotensin-converting enzyme inhibitor. Rentiapril has a monoisotopic molecular weight of 313.04 Da.
Synonyms	Rentiapril
Categories	Acids, Acyclic Agents Acting on the Renin-Angiotensin System Angiotensin-Converting Enzyme Inhibitors Antihypertensive Agents Cardiovascular Agents Enzyme Inhibitors Propionates Protease Inhibitors Sulfhydryl Compounds Sulfur Compounds Thiazoles
CAS number	80830-42-8

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.