ACA

6-AMINOHEXANOIC ACID

Created:	1999-07-08
Last modified:	2024-09-27

Find Related PDB Entry
20 entries where ACA is found as a standalone ligand10 entries where ACA is covalently linked to polymer or other heterogen groups 29 entries where ACA is found in a polymer sequence

Help Find related ligands:
Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Help

Find related ligands:

Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Chemical Details
Formal Charge	0
Atom Count	22
Chiral Atom Count	0
Bond Count	21
Aromatic Bond Count	0

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	6-AMINOHEXANOIC ACID
Synonyms	AMINOCAPROIC ACID
Systematic Name (OpenEye OEToolkits)	6-aminohexanoic acid
Formula	C₆ H₁₃ N O₂
Molecular Weight	131.173
Type	PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)CCCCCN
SMILES	CACTVS	3.341	NCCCCCC(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C(CCC(=O)O)CCN
Canonical SMILES	CACTVS	3.341	NCCCCCC(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C(CCC(=O)O)CCN
InChI	InChI	1.03	InChI=1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChIKey	InChI	1.03	SLXKOJJOQWFEFD-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00513
Name	Aminocaproic acid
Groups	approved investigational
Description	An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Synonyms	6-aminohexanoic acid 6-Aminocaproic acid acidum aminocaproicum Acide aminocaproïque omega-Aminocaproic acid Epsilon-Aminocaproic acid Aminocapronsäure Aminocaproic acid Epsilon Aminocaproic Acid omega-Aminohexanoic acid EACS Ácido aminocapróico epsilon-Aminohexanoic acid Epsilcapramine EACA
Brand Names	Amicar Injection - Liq IV 250mg/ml Hea YanToothpaste 28tak Gum Care Tooth Aminocaproic Acid Dr.LORD Green Propol Tooth Hae Yan Tooth Rootsallo Toothpaste Clean Breath Tooth Gray Salt Tooth Solmeet denti doctor Solmeet Greensaltrain Tooth NAVI Black and C-Clinic Amicar Inj 250mg/ml Exoden White Tooth Mastikis Mastic 24K Amicar - Syr 250mg/ml Yumaki Original Mint Tooth Salt Tooth Amicar Syr 250mg/ml BAMBOO SALT Eunganggo Jook Yeom Toothpaste Saltrain Tooth Mastikis Gold Amicar Amicar Tab 500mg LACSIAN new perfect all care tooth Solco Platino Iondenti Tooth Aminocaproic acid Dr.EL GUM CARE TOOTH HiMangChanToothpaste Gray Salt Relief and Nature Toothpast E Jasmine Mint Mastikis Mastic GumCare BAMBOO SALT Eunganggo Jook Yeom Amicar - Tab, 500mg
Indication	For use in the treatment of excessive postoperative bleeding.
Categories	Acids, Acyclic Amino Acids Amino Acids, Peptides, and Proteins Aminocaproates Antifibrinolytic Agents Blood and Blood Forming Organs Caproates Coagulants Decreased Fibrinolysis Fibrin Modulating Agents Hematologic Agents Hemostatics
ATC-Code	B02AA01
CAS number	60-32-2

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Plasminogen	MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECA...	unknown	inhibitor
Tissue-type plasminogen activator	MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIY...	unknown	antagonist
Apolipoprotein(a)	MEHKEVVLLLLLFLKSAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQ...	unknown	other
Aldehyde oxidase	MDRASELLFYVNGRKVIEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCG...	unknown	substrate

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
Pharos	CHEMBL1046
PubChem	564, 517030
ChEMBL	CHEMBL1046
ChEBI	CHEBI:16586, CHEBI:57826, CHEBI:79212
CCDC/CSD	ZEMCIG, ZEMCEC, ZEMCAY, ZEMCUS, AMCAPR11, JIZHEF, EZOGAD, JIHFUE, QEGFIR, AMCAPR10, GAHHIK