ACA

6-AMINOHEXANOIC ACID

Created:	1999-07-08
Last modified:	2024-09-27

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20 entries where ACA is found as a standalone ligand10 entries where ACA is covalently linked to polymer or other heterogen groups 29 entries where ACA is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	22
Chiral Atom Count	0
Bond Count	21
Aromatic Bond Count	0

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Chemical Component Summary
Name	6-AMINOHEXANOIC ACID
Synonyms	AMINOCAPROIC ACID
Systematic Name (OpenEye OEToolkits)	6-aminohexanoic acid
Formula	C₆ H₁₃ N O₂
Molecular Weight	131.173
Type	PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)CCCCCN
SMILES	CACTVS	3.341	NCCCCCC(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C(CCC(=O)O)CCN
Canonical SMILES	CACTVS	3.341	NCCCCCC(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C(CCC(=O)O)CCN
InChI	InChI	1.03	InChI=1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChIKey	InChI	1.03	SLXKOJJOQWFEFD-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB00513
Name	Aminocaproic acid
Groups	approved investigational
Description	An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Synonyms	Acide aminocaproïque Epsilon-Aminocaproic acid EACS Epsilcapramine omega-Aminohexanoic acid Aminocaproic acid EACA acidum aminocaproicum 6-aminohexanoic acid omega-Aminocaproic acid Ácido aminocapróico Aminocapronsäure Epsilon Aminocaproic Acid 6-Aminocaproic acid epsilon-Aminohexanoic acid
Brand Names	BAMBOO SALT Eunganggo Jook Yeom Toothpaste HiMangChanToothpaste 28tak Gum Care Tooth Amicar - Syr 250mg/ml Aminocaproic Acid BAMBOO SALT Eunganggo Jook Yeom NAVI Black and C-Clinic Solco Platino Iondenti Tooth Gray Salt LACSIAN new perfect all care tooth Amicar Dr.LORD Green Propol Tooth Solmeet denti doctor Gray Salt Tooth Hea YanToothpaste Greensaltrain Tooth Yumaki Original Mint Tooth Amicar Tab 500mg Mastikis Mastic 24K Rootsallo Toothpaste Dr.EL GUM CARE TOOTH Amicar Inj 250mg/ml Aminocaproic acid Mastikis Mastic GumCare Exoden White Tooth Mastikis Gold Amicar Syr 250mg/ml Solmeet Clean Breath Tooth Relief and Nature Toothpast E Jasmine Mint Amicar - Tab, 500mg Amicar Injection - Liq IV 250mg/ml Hae Yan Tooth Salt Tooth Saltrain Tooth
Indication	For use in the treatment of excessive postoperative bleeding.
Categories	Acids, Acyclic Amino Acids Amino Acids, Peptides, and Proteins Aminocaproates Antifibrinolytic Agents Blood and Blood Forming Organs Caproates Coagulants Decreased Fibrinolysis Fibrin Modulating Agents Hematologic Agents Hemostatics
ATC-Code	B02AA01
CAS number	60-32-2

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Plasminogen	MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECA...	unknown	inhibitor
Tissue-type plasminogen activator	MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIY...	unknown	antagonist
Apolipoprotein(a)	MEHKEVVLLLLLFLKSAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQ...	unknown	other
Aldehyde oxidase	MDRASELLFYVNGRKVIEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCG...	unknown	substrate

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
Pharos	CHEMBL1046
PubChem	564, 517030
ChEMBL	CHEMBL1046
ChEBI	CHEBI:57826, CHEBI:16586, CHEBI:79212
CCDC/CSD	ZEMCIG, ZEMCEC, ZEMCAY, ZEMCUS, AMCAPR11, JIZHEF, EZOGAD, JIHFUE, QEGFIR, AMCAPR10, GAHHIK