ACD

ARACHIDONIC ACID

Created:	1999-07-08
Last modified:	2024-09-27

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33 entries where ACD is found as a standalone ligand1 entries where ACD is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	54
Chiral Atom Count	0
Bond Count	53
Aromatic Bond Count	0

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Chemical Component Summary
Name	ARACHIDONIC ACID
Systematic Name (OpenEye OEToolkits)	(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid
Formula	C₂₀ H₃₂ O₂
Molecular Weight	304.467
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC
SMILES	CACTVS	3.341	CCCCCC=CCC=CCC=CCC=CCCCC(O)=O
SMILES	OpenEye OEToolkits	1.5.0	CCCCCC=CCC=CCC=CCC=CCCCC(=O)O
Canonical SMILES	CACTVS	3.341	CCCCC/C=C\C\C=C/C/C=C\C\C=C/CCCC(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)O
InChI	InChI	1.03	InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-
InChIKey	InChI	1.03	YZXBAPSDXZZRGB-DOFZRALJSA-N

Drug Info: DrugBank

DrugBank ID	DB04557
Name	Arachidonic Acid
Groups	experimental
Description	An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. [PubChem]
Synonyms	Arachidonic Acid
Categories	Arachidonic Acids Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 Substrates Eicosanoids Fatty Acids Fatty Acids, Essential Fatty Acids, Unsaturated Lipids
CAS number	506-32-1

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Peroxisome proliferator-activated receptor alpha	MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFG...	unknown
Bile acid receptor	MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQN...	unknown	ligand
Retinoic acid receptor RXR-alpha	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSP...	unknown
Prostaglandin G/H synthase 1	MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFG...	unknown
14 kDa fatty acid-binding protein	MSSFLGKWKLSESHNFDAVMSKLGVSWATRQIGNTVTPTVTFTMDGDKMT...	unknown
Cytochrome P450 2C9	MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDI...	unknown	substrate
Fatty acid-binding protein, intestinal	MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTV...	unknown
Serum albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown
Fatty acid-binding protein, adipocyte	MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVI...	unknown
Solute carrier organic anion transporter family member 2A1	MGLLPKLGASQGSDTSTSRAGRCARSVFGNIKVFVLCQGLLQLCQLLYSA...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682