AIN

2-(ACETYLOXY)BENZOIC ACID

Created:	2004-04-08
Last modified:	2020-05-26

Find Related PDB Entry
8 entries where AIN is found as a standalone ligand

Help Find related ligands:
Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Help

Find related ligands:

Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Chemical Details
Formal Charge	0
Atom Count	21
Chiral Atom Count	0
Bond Count	21
Aromatic Bond Count	6

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	2-(ACETYLOXY)BENZOIC ACID
Synonyms	ACETYLSALICYLIC ACID; ASPIRIN
Systematic Name (OpenEye OEToolkits)	2-acetyloxybenzoic acid
Formula	C₉ H₈ O₄
Molecular Weight	180.157
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(Oc1ccccc1C(=O)O)C
SMILES	CACTVS	3.341	CC(=O)Oc1ccccc1C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	CC(=O)Oc1ccccc1C(=O)O
Canonical SMILES	CACTVS	3.341	CC(=O)Oc1ccccc1C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	CC(=O)Oc1ccccc1C(=O)O
InChI	InChI	1.03	InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
InChIKey	InChI	1.03	BSYNRYMUTXBXSQ-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00945
Name	Acetylsalicylic acid
Groups	approved vet_approved
Description	Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer [A177325]. Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others [L5968]. Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
Synonyms	Acetylsalicylsäure Aspirin o-carboxyphenyl acetate 2-Acetoxybenzoic acid Acetylsalicylate ASA Acidum acetylsalicylicum Azetylsalizylsäure acide 2-(acétyloxy)benzoïque o-acetoxybenzoic acid Polopiryna Lysine acetylsalicylate Aspirina Acide acétylsalicylique Salicylic acid acetate Acetylsalicylic acid ácido acetilsalicílico O-acetylsalicylic acid 2-Acetoxybenzenecarboxylic acid
Brand Names	Alka-Seltzer Plus Cold Orange Zest Aspirin Coated Caplets 500mg Ac and C Tab 1/8gr Alka-Seltzer Plus Night Cold Formula (Lemon) Medi First Plus Pain Ache Sunmark Aspirin Regular Strength Asa Ect 600mg Extra Strength Headache, Caseys 4good Aspirin Chewable Tablets 325mg Pain Relief Extra Strength Dg Health Aspirin Excedrin Migraine, TRAVEL BASIX Aspirin 81 mg Enteric Coated Medi-First Aspirin 4215 First Aid Kit Coricidin D Tab MEDI-FIRST Aspirin Berkley and Jensen Aspirin Aspirin chewable low dose Coated Daily Low Dose Asa 81 mg GOODYS Hangover Entrophen 325mg Caplets aspirin Regular strength Aspirin Granules Leader Migraine Relief Seedalmerk Coated Aspirin - Ect 80mg Walgreens Pain Relief Powder Smart Sense Effervescent Cold Relief Effervescent Cold Relief Safety Coated Aspirin 81 mg Low Dose Orphenadrine Citrate Aspirin Caffeine Acetaminophen Aspirin and Caffeine Oxycodone Hydrochloride and Aspirin Bc Cherry Medi First Plus Tri Buffered Aspirin Trianal Tablet Coricidin Tab Asprin Excedrin Extra Strength and Excedrin Tension Headache Regular strength aspirin Zee-Seltzer Antacid and Pain Reliever Handy Solutions Headache Pain Relief Adult Aspirin Regimen 4244 First Aid Kit Pal-pravastatin-asa BAYER Aspirin Extra Strength Caplets Asa Tablets USP 325 mg Effervescent Antacid and Pain Relief Health Mart Regular Strength Enteric Coated Aspirin Butalbital, Aspirin, and Caffeine Basic Care Aspirin Aspirin Enteric Safety Coated Acetylsalicylic Acid Coated Excedrin PM Triple Action Caplets and Excedrin Extra Strength Pain Reliever Xpect Pain Away Smart Sense Effervescent Antacid and Pain Relief ARC FIRST AID Emergency Preparedness Contains 167 PIECES Good Sense Effervescent Antacid and Pain Relief ARC FIRST AID Contains 303 PIECES HARDCASE Tylo Migraine (Acetaminophen) Neutra-seltzer Alka-Seltzer Plus Cold Medicine Sparkling Original Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Good Sense Migraine Formula Aspirin Extra Strength With Stomach Guard Medpurine Aspirin 81mg Enteric coated Delayed Release Leader Aspirin 4251 First Aid Kit Chronic Pain/Fever Relief Fiorinal Tab Robaxisal C 1/2 Headache Relief Extra Strength GenCare Headache Relief 4355 First Aid Kit Ascomp with Codeine Aspirin 325 Mg EC Antidol Tablets Aspirin Stomach Guard Extra Strength Crane Safety Aspirin Phenaphen No.4 Cap Headache Relief Added Strength Instantine Tab K-Mart SmartSense First Aid Contains 101 Pieces Aspir Low Aspirin Regimen 4376 First Aid Kit Entrophen 80mg Pain Reliever Added Strength Pronal C1/4 Capsules Zee Aspirin Butalbital, Aspirin, Caffeine, and Codeine Phosphate Deluxe Dental Emergency Kit Regular Strength Enteric Coated Aspirin Synalgos Extra Strength Headache Relief Sns-asa EC Aspirin Adult low dose Goodys PM Pain Reliever Enteric Aspirin Regular Strength Premier Value Antacid and Pain Relief Medicine Care One migraine relief Regular Strength Enteric coated aspirin A.S.A. Acetaminophen Aspirin Caffeine Asadol 650mg Aspirin Adult Low Dose Aspirin 81 MG C2 Buffered Tab First Aid Direct Chewable Aspirin GENUINE FIRST AID Emergency Preparedness Contains 167 Pieces Safety Coated Aspirin 325 mg Regular Strength Low Dose Aspirin Low Dose Alka-Seltzer Plus Severe Cold Powerfast Fizz Night Solves - aspirin Cherry Aspirin Adult low strength Uline Aspirin Excedrin Extra Strength Geltabs 4342 First Aid Kit ShopRite Migraine Formula Sunmark migraine relief Excedrin Extra Strength Caplets Asa EC 80 4232 First Aid Kit Anacin ES Enteric Aspirin Headache Relief to Go Yosprala Acetylsalicylic Acid, Caffeine & 8 Mg Codeine Phosphate Tablets Bi Electro Extra Strength Aspirin Migraine Childrens Aspirin Lowprin 80mg ENTERIC COATED ASPIRIN Regular Strength Alka-Seltzer Extra Strength Medi First Plus Pain Zapper 4291 First Aid Kit Lowprin 325 Chewable Tablet Pain Stoppers EX Migraine Formula Best Choice Pain Relief Powder Asa 975 Tab Bromo Seltzer Coricidin Nd Tab Equaline Effervescent Cold Relief Bufferin Low Dose Buffered Aspirin Low Dose Aspirin Darvon N Compound Pulvule 405 Aspirin Stomach Guard Regular Strength PMS-pharnal-C 1/4 Capsules Excedrin Migraine Geltabs Extra Strength Pain Aid Bubbles R Better Effervescent Cold Relief GOODYS Extra Strength Headache Mixed Fruit Blast Excedrin Migraine, CVP HEALTH 4240 First Aid Kit Phenaphen No 3 Cap Pro-aas EC Medi First Pain Ache Protection 4227 First Aid Kit Coryphen 325 Codeine 30 Tab Aspirin Plus Stomach Guard Extra Strength Good Sense Headache Relief ASPIRIN Low Dose Rugby Adult Aspirin Top Value Effervescent Cold Relief - Orange 4303 First Aid Kit Ag-asa Chew Viva Asa 325 mg Aspirin Adult Low Strength Regular Strength Tri-Buffered Aspirin 4221 First Aid Kit Medi First Plus Aspirin Enteric Coated Asa 325 mg C T Acetylsalicylic Acid Codeine and Caf Tab Good Neighbor Pharmacy Headache Relief Aspirin Tablets 325mg Natural Aspirin plus Immune Supporting Dietary Supplement ARC FIRST AID Contains 404 PIECES Migralex Dr. Mauskop Aspirin Low Strength, Enteric Asa 325mg Aspirin Delayed Release Aspirin Express Pack Leader Extra Strength Effervescent Antacid and Pain Reliever Flanax Aspirin Pain Reliever Equate Migraine Relief Asa-325 Comprimes Retard Bayer Advanced Aspirin Extra Strength Arthriten Inflammatory Pain Formula Anacin Tablet Top Value Effervescent Pain Relief 292 Tablets Zee Pain Aid 4134 First Aid Kit Blowfish ALKA SELTZER PLUS Cold Day and Night Effervescent Easy Care First Aid Kit - Comprehensive 4249 First Aid Kit Ascriptin Maximum Strength Buffered Aspirin Sedal3x Orphenadrine Citrate, Aspirin and Caffeine BAYER 500 mg Headache Tab 300mg CAREALL Aspirin 4224 First Aid Kit BC Cherry 4387 First Aid Kit A.S.A. Enteric Coated Tab 325mg Clopidogrel Kit Effervescent Cold Relief - Orange 4365 First Aid Kit Lowprin Aspirin and Extended-release Dipyridamole Equaline Effervescent Antacid and Pain Relief MEDIQUE Aspirin BUTALBITAL, ASPIRIN, CAFFEINE and CODEINE PHOSPHATE Extra Strength Headach Relief Aspirin Plus Stomach Guard Tab Smart Sense Chewable Aspirin Asa 80 Leader Cardinal Health Aspirin A.S.A. 325 Mg Tablet Equaline Aspirin 50 Person ANSI Kroger Effervescent Antacid and Pain Relief Enteric Coated Low Dose Aspirin Enteric coated aspirin Regular strength 282 Mep Tab Apo Asa Tab 325mg Fiorinal Aspirin 50 CT Buffered Aspirin Signature Care Migraine Relief Exaprin-AC Aspirin 325 mg Pro-aas - 80 (croquable) Equate Effervescent Antacid and Pain Relief Tri-Buffered Aspirin Regular Strength Anacin Extra Strength Tablet Dr Pausins Aspirin Pain Terminator Calmine Tab 692 Tab Bayer Low Dose Sunmark aspirin adult low strength 4246 First Aid Kit Endodan Equagesic Tablets Extra Strength Midol EC-81Aspirin Enteric Coated Methoxisal-C 1/8 Equate Extra Strength Effervescent Antacid and Pain Relief Up and Up Antacid and Pain Relief C2 Buffered With Codeine Tab Adventure Medical Kits 1-4 Person First Aid Aspirin Safety Coated Rx Act headache formula added strength Fasprin Pain Relief Maximum Strength 4142 First Aid Kit Bayer Aspirin Chewable Excinol Migraine (Acetaminophen) Acetylsalicylic Acid Extra Strength 500mg Tablets USP Phenaphen No 4 Cap Lo-asa 80mg Chewable - Tab FormuCare Aspirin Berkley and Jensen Migraine Formula Entrophen Ect 500mg Asa-caffeine-codeine Acetylsalicylic Acid A.S.A. Tablets 325mg Excedrin PM Triple Action Caplets and Excedrin Tension Headache Regular Strength Asa 4154 First Aid Kit Good Sense headache formula added strength Muscle Relaxant and Back Pain Relief Regular Strength Tablets Alka-Seltzer Plus Cold Sparkling Original PowerFast Fizz Pain Away Plus Bayer Aspirin Handy Solutions GENUINE ASPIRIN BAYER Entrophen Asa EC Bayer Migraine Formula Equaline aspirin adult low dose Enteric Coated Asa Tablets 650mg Enteric Coated Aspirin regular strength Aspirin Enteric Safety-Coated Excedrin Menstrual Complete Effervescent Pain Relief Enteric Coated A.S.a Aspirin 325 Asaphen EC Medique Pain Off Ready America First Aid Pocket - 33 Pieces Chewable Adult Low Dose Aspirin Ready America First Aid Outdoor- 107 Pieces Extra Strength Back and Body Leader Headache Formula Added Strength Aspirin Coated for Delayed Release Regular Strength Dolomine 37 Euro Asa Migraine Relief 4356 First Aid Kit Dolodol Basic Care Migraine Relief Headache Formula Extra Strength Acetaminophen, Aspirin, Caffeine 4304 First Aid Kit Walmart Pain Relief Powder Pharbest Aspirin 325mg Regular Strength Aspirin Aspirin 81 mg Buffered Aspirin Regular Strength Hydrocodone Bitartrate and Aspirin ULINE Aspirin Effervescent Pain Relief Fast Relief Fast Relief Rx Act Aspirin Acetylsalicylic Acid Extra Strength Stomach Protection 500mg Caplets Excedrin Migraine Uricalm Intensive Plus Pharma NSAID Aspirin Genuine Aspirin FIRST AID Contains 303 PIECES HARDCASE Adalat XL Plus Pain Aid ESF Pain Stopper Extra Aspirin Enteric Coated Caplet 325mg Ru-21 Hangover Relief Right Remedies Aspirin Low Dose 81 mg Butalbital, Aspirin, Caffeine and Codeine Phosphate Signature Care Aspirin Aramark Pain-Free Extra Strength Bayer AM extra stength Lil Drug Store Aspirin 325 Adult Low Dose BackAid Inflammatory Pain Formula Methocarbamol and Aspirin Topcare Headache Relief Alka-Seltzer Plus Multi-Symptom Cold and Cough Aspirin Chewable Tablets Bufferin Regular Strength Pain Relief Duoplavin DG Health migraine relief K-Mart SmartSense First Aid Contains 303 Pieces Pain Relief Aspirin Low Dose Headache, Circle K Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces Value PharmaPain Reliever Extra Strength Aspirin to Go Meijer Effervescent Antacid and Pain Relief Aspirin Regular Strength Aspirin Chewable Tablets - 325mg 365 Everyday Value Aspirin Natural Aspirin plus Tart Cherry Dietary Supplement St. Joseph Chewable Aspirin Plus Pharma NSAID 325 mg Pro-aas EC - 80 Aspirin 81 mg Low Dose Quality Choice Extra Strength Effervescent Antacid and Pain Relief Aspirin 81 Vanquish Nervine Tab Quality Choice Effervescent Cold Relief Plus Alka-Seltzer Plus Cold Day and Night Fiorinal with Codeine Alka-Seltzer Plus Day and Night Cold Medique at Home Aspirin Norgesic Forte 4209 First Aid Kit Madelon Excedrin Extra Strength St. Joseph Low Dose Aspirin Quality Choice Effervescent Antacid and Pain Relief Family Wellness Pain Relief Powder Asatab EC 325mg Healthy Accents migraine formula Caring Mill Migraine Relief Rivasa 80mg Croquable - Tab A.C. & C 8mg Tab Harris Teeter Migraine Relief Low Strength Chewable Aspirin Butalbital, Aspirin and Caffeine 4395 First Aid Kit Quality Choice Pain Relief Powder Adult Low strength Aspirin MEDIQUE Tri Buffered Aspirin ShopRite Aspirin Aspirin Enteric Coated Asa 650 mg Nra-asa 80 Mg Croquable Asa Suppositories 650mg Alka-Seltzer Plus Cold Sparkling Original McKesson Aspirin Smart Sense migraine relief Top Value Effervescent Cold Relief Aspirin Safety Coated Adult Low Dose 4250 First Aid Kit Bio-asa Aspergum 325 Mg (cherry) Asa Daily Low Dose Extra Strength Muscle & Back Pain Relief With Asa 282 Tab Lowprin 325 FIRST AID Contains 1000 PIECES GOOD NEIGHBOR PHARMACY FIRST AID Contains 202 PIECES Jamp-asa EC Ascriptin Regular Strength Buffered Aspirin Asa Acetylsalicylic Acid Bayer Genuine Aspirin Acetaminophen, Aspirin and Caffeine Alka-Seltzer Lemon Lime dihydrocodeine bitartrate and aspirin and caffeine DC Asaphen Plus 325 Low Dose Aspirin 81 mg Safety Coated First Aid Direct Aspirin Extra Strength Pain Reliever Moore Medical Aspirin Vida Mia Pain Relief Teva-tecnal C 1/2 Asa Ect 325mg Aspirin With Stomach Guard 4333 First Aid Kit Rivasa 80 Mg EC Aspirin Chewable, Low Dose MooreBrand Aspirin Muscle and Back Pain Relief With Asa Headache Relief Bufferin M-asa 80 Mg Croquable Pain Reliever Extra Strength Ache and Pain Relief to Go Circle K Aspirin 325 Aspirin and Omeprazole Delayed-release Tab Lab Safety and Supply Tri Buffered Aspirin Regular Strength Pain Relief Alka-Seltzer Plus Severe Cold Night PowerFast Fizz Equate Aspirin Chewable Norgesic Tab Pravigard Pac Enteric Coated Asa Daily Low Dose 7 Select Adult Chewable Aspirin Market Basket Effervescent Antacid and Pain Relief Effervescent Pain Relief Fast Relief GFA First Aid 75 Person Metal Case 217 Strong Tab 10 Person ANSI Methoxisal Extra Strength Topcare Aspirin Pamprin Max Menstrual Pain Relief Alka-Seltzer Plus Cold Formula (Orange Zest) Equaline headache formula added strength Aspirin - Children's Size - Tablets Bayer Rapid Relief Aspirin Enteric Coated, Regular Strength Care One Aspirin 4229 First Aid Kit MYGRIN Nighttime Basic Dental Emergency Kit Vazalore Aspirin, Caffeine, and Dihydrocodeine Bitartrate Dr. Waynes Aspirin Low Dose Adult Aspirin Regimen Low Dose Acetylsalicylic Acid Tab 325mg BP Dr Pausins Low Dose Chewable Aspirin Cherry Flavor Up and Up Migraine Relief HyVee Health Effervescent Antacid and Pain Relief Tri-buffered Asa Tab Muscle Relaxant and Analgesic North Aspirin Pharbest Regular Strength Aspirin Caring Mill Aspirin Oxycodone and Aspirin pain relief aspirin Low Dose Walgreens Effervescent Cold Relief Plus Kirkland Signature Migraine Relief Teva-tecnal Equaline migraine formula Herbopyrine Tab 325mg Aspirin Low Dose Cove Migraine Relief Amazon Basic Care Migraine Relief C2 Tab With Codeine Kirkland Signature Migraine Headache Relief Norgesic Forte Tab Basic Care Headache Relief Norgesic Aspirin Low Dose Safety Coated Anacin Extra Strength Caplets Alka Seltzer Originial 1s Blister Pack Family Wellness Migraine Coated Daily Low-dose Asa NobleAid PAIN RELIEVER Safety Coated Low Dose Aspirin Genuine First Aid Industrial First Aid ARC FIRST AID Contains 101 PIECES Hardcase FIRST AID Contains 101 PIECES Asa 81 mg A.C. & C. 8 mg Aspirin Pain reliver CVS All Purpose First Aid Kit Rite Aid Antacid and Pain Relief Alka-Seltzer Plus Night Cold Medicine Chewable Low Dose Aspirin Aspirin Night-time Only For FIRST AID MEDICINE 4332 First Aid Kit Butalbital, aspirin, and caffeine Medique Products Aspirin Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mg Aspirin - Children's Size 80mg A.S.A. Tablets 5gr BP Aspirin adult low strength 4217 First Aid Kit Robaxisal Extra Strength Excedrin PM Triple Action Caplets Excedrin Extra Strength Pain Reliever Coryphen 650 Codeine 30 Tab ASPIRIN 81 MG Low Dose A & C Tablets With Codeine 30mg Aspirin Low Strength Adult Uncoated Aspirin Topcare Migraine Relief Extra Strength Aspirin enteric coated aspirin Regular Strength Rexall Coated Daily Low Dose Asa Aspirin and Dipyridamole Extended Release Low Dose Chewable Aspirin Back and Body Extra Strength Ecotrin Regular Strength Genuine Bayer Aspirin Novo-propoxyn Compound Cap Excedrin Extra Strength Headache Health Mart Adult Aspirin St. Joseph Safety Coated Aspirin Pain Relief PM Carisoprodol, Aspirin and Codeine Phosphate Leader migraine formula Extra Strength Midol Relief Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange 4196 First Aid Kit Low Dose Miniprin Enteric Safety Coated Rexall Aspirin Acetylsalicylic Acid Stomach Protection 325mg Tablets Picot Plus Effervescent WinCo Foods Effervescent Cold Relief Arco Pain Tab Pronal Capsules Alka-Seltzer Plus Multi-Symptom Cold Night Acetylsalicylic Acid Tab 300mg Added Strength Pain Reliever Fiorinal-C 1/4 Rivacodan Bayer Aspirin Regimen enteric coated Goodys Migraine Relief BLUE ACME SLEEVE FIRST AID Contains 1000 PIECES Good Sense Effervescent Cold Relief Muscle & Back Pain Asa 325 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 325 mg Painex Tab 0.5gr Pain Free Careone Aspirin Advanced Aspirin Alka-Seltzer Hangover Relief Halfprin Low Dose Robaxisal C-1/8 Tablets Clopidogrel/acetylsalicylic Acid Zentiva AspirinLow Dose Low Dose Leader Low Dose Aspirin Aspirin EC TopCare Aspirin Aspirin regular strength Asa Tab 325mg HyVee Health Effervescent Cold Relief Acetaminophen 250mg Aspirin 250mg Caffeine 65mg Extra Strength Muscle & Back Pain Asa 500 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 500 mg 81 mg Low Dose Aspirin Leader Effervescent Antacid and Pain Relief Stanback GENUINE FIRST AID Emergency Preparedness Contains 167 PIECES HARDCASE Asa Suppositories 150mg Bufferin Extra -strength 4388 First Aid Kit Pain Relief Fast Relief Physicians Care Extra Strength Pain Reliever 4211 First Aid Kit PMS-asa EC Alka-Seltzer Plus Cold and Cough Adult Low Dose Aspirin Enteric Coated ARC FIRST AID Contains 303 PIECES Henry Schein Aspirin 222 Tablets Low dose aspirin 81mg Praxis Asa EC 81 Mg Daily Low Dose 217 Percodan-demi Muscle and Back Pain Relief Extra Strength Robaxisal Tablets 4389 First Aid Kit Alka-Seltzer Plus Cold Formula (Cherry Burst) 4305 First Aid Kit Entrophen Ect 650mg Anacin Extra Strength 4340 First Aid Kit Clopidogrel/acetylsalicylic Acid Mylan Alka-Seltzer Plus Severe Cold and Flu Aspica (Aspirin) Medi-First Plus Aspirin Enteric Coated A.S.A. Enteric Coated Asa Tablets 325mg Teva-tecnal C 1/4 Bayer Headache Relief Extra Strength Headache, Circle K Dristan Capsules Family Wellness Effervescent Cold Relief Original Aspirin Low Dose Enteric Coated Bayer Back and Body Extra Strength Circle K Headache Relief Dollar General Headache Powders Alka-seltzer Flavoured - Evt Aspir-81 Green Guard Extra Strength Pain Relief pain relief back and body EXTRA STRENGTH Lab Safety Supply Aspirin WinCo Foods Effervescent Antacid and Pain Relief BC Arthritis Coryphen 325 Tab Equate Daily Low-dose Dry Socket Paste Headache Formula Added Strength Rapidol Aspirin Display 2x25 Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry Flavored Aspirin 81mg Alka Seltzer Original Thrulife Extra Strength Headache Relief Equate Aspirin Kroger Effervescent Cold Relief Soma Bc Max Chewable Daily Low Dose Asa Entrophen Chewable Pain Stoppers Chewable Aspirin Adult low dose 282 Tablets FIRST AID Contains 404 PIECES Foster and Thrive Migraine Relief Healthy Accents Aspirin Cardiospirina 81 mg Tabletas con cubierta enterica Healthy Accents headache relief added strength Nezger Tab Physicians Care Aspirin 292 Tab Ana-dent Biovanta Trip Action Tart Cherry and Honey Muscle Relaxant and Back Pain Relief Extra Strength Tablets HEALTH SENSE Adult Chewable Low Strength Aspirin Asa Ect 650mg Extra Pain Relief Effervescent Orange Cold Relief Jamp-asa Chew Enteric Coated Aspirin Enteric Coated Daily Low Dose Asa 81 mg Low dose Aspirin Low Dose Aspirin Chewable Publix Super Markets Inc Low Dose Aspirin Enteric Safety Coated Aspirin and Extended-Release Dipyridamole Good Neighbor Pharmacy Aspirin Splizz Pain Reliever - Grapefruit-flavored Mountain Series Weekender Medical Reese Headache Powders Pain Relief Aspirin Aspirin and Dipyridamole Aspirin Enteric Coated Health Mart Aspirin Natural Aspirin plus Lemon and Honey Dietary Supplement ARC FIRST AID Contains 101 PIECES SohMed Pain Reliever Aspirin With Stomach Guard Extra Strength - Tab A.S.A. With Methocarbamol Night-time Extra Strength Micro-Coated Aspirin Tabcin 500 Trianal C¼ Bayer Fast Release Asa 500 Mg Tablets Extra Strength Methoxisal-C 1/2 PMS-pharnal-C1/2 Capsules Bayer PM Alka Seltzer Plus Cold Pronal Tablets MICRO-COATED ASPIRIN 325 mg Trianal C½ Up and Up Aspirin A.S.A. (acetylsalicylic Acid) Tab 325mg USP CVS Health Antacid and Pain Reliever PHL-asa Aspirin Low Dose Sugar Free Best Choice Effervescent Cold Relief Spasmhalt-asa-8 Dg Health Headache Relief Family Wellness Migraine Relief EXCEDRIN MIGRAINE acetaminophen, aspirin (nsaid) and caffeine Alka-Seltzer Plus Euro-asa EC FIRST AID Contains 303 PIECES Publix Fast Relief Effervescent Aspirin 81mg Enteric coated Low Strength Aspirin Regimen Adult Low Strength Aspirin 4213 First Aid Kit 4248 First Aid Kit FIRST AID Contains 202 PIECES Good Neighbor Pharmacy Aspirin Enteric Safety Coated A.C.& C Tablets Goodys Cool Orange Headache Alka-seltzer Flavoured Low Dose Aspirin Enteric Safety-Coated Muscle and Back Pain Relief With Asa Extra Strength Extra Strenght Headache Relief Asa-650 Comprimes Retard Alka-seltzer Original Pain Reliever 4230 First Aid Kit Alka-Seltzer Plus Severe Cold PowerFast Fizz Orange Zest Pain Stoppers Extra Smart Health Aspirin Regular Strength Sunmark Headache Relief Sunmark Migraine Relief Travel Savvy Aspirin FIRST AID Contains 101 PIECES HARDCASE Aramark Pain Free Super Extra Strength Aspirin Backache Aspirin Coated Caplets 325 mg PMS-pharnal Capsules Enteric Coated Asprin Low Dose Asa 80 mg Dg Health Headache Relief Added Strength Childrens Low Dose Aspirin Phenaphen No.2 Cap Bayer Headache Jamp-asa 81mg EC Adult Low Dose Aspirin Enteric Safety Coated Asprin and Extended-release Dipyridamole Citramon Aspirin 5 grain Good Sense Aspirin Medi First Pain Relief Dolex Forte Ag-asa EC Dr Pausins Low Dose Chewable Aspirin Orange Flavor Chewable Aspirin Acido Acetilsalicilico With enteric coat Enteric Coated A.S.a (caplet) Pain Reliever Plus 7 Select Aspirin Alka-Seltzer XTRA STRENGTH Headache relief Extra Strength Ac&c Tablets Extra Strength Asa 500mg Alka-Seltzer Plus Day Non Drowsy Cold Medicine Citrus Health Mart Migraine Formula Geritrex Aspirin Asa Topcare Migraine Formula Anacin Aspirin Arthritis Pain Relief 650 mg Aspirin Safety coated Equagesic 4214 First Aid Kit Aggrenox Ecotrin Fairfield Health Products Extra Strength Goodys Extra Strength London Drugs Coated Daily Low-dose Asa Extra Strength Pain Relief GFA First Aid Kit Essentials - 33 Pieces 692 Tablet Instantine - Tablets Aspirin Backache Cardiaspirin Protect 4216 First Aid Kit Asa Extra Strength Caplet 500mg Teva-oxycodan Health Mart Migraine Relief Butalbital Compound Pain Stoppers Regular Aspirin Enteric ARC FIRST AID Contains 1000 PIECES Adventure Medical Kits 1-2 Person First Aid Arthriten Max Aspirin Extra Strength Plus Bayer Advanced Aspirin Regular Strength Lil Drug Store Headache Relief Extra Strength Safety Coated Aspirin Asadol 325mg Critical Care Aspirin to Go Aspirin enteric safety coated Aspergum Orange 325 mg Green Guard Pain and Ache Relief Direct Safety Aspirin 7 Select Migraine Formula Phenaphen No 2 Cap Aspirin E-C Low Dose Safety Coated Chewable Aspirin Low Dose Alka Seltzer Plus 1s Blister Pack Apo-asa Ld DG Health Effervescent Antacid and Pain Relief Dollar General Effervescent Cold Relief Miniprin Tri-Buffered Aspirin Alka-Seltzer Plus Severe Cold PowerFast Fizz Anacin With Codeine Tab A.S.A. Enteric Coated Tab 650mg Pronal - C1/2 Capsules Headache Pain Reliever Headache Relief PM Meijer Effervescent Cold Relief Alka Seltzer Flavoured Family Wellness Effervescent Antacid and Pain Relief Entrophen 650mg Caplet Ect Xpect Pain Away Extra Strength Low dose Chewable Aspirin Good Sense aspirin Medique Medi Seltzer Robaxisal C 1/4 Care One Original Antacid and Pain Relief Alka Seltzer First Aid Only Aspirin Aspirin Enteric Coated Low Dose Methoxisal Assured Aspirin Adults Low Strength Aspirin Good Neighbor Pharmacy aspirin orange flavor chewable Adult Chewable Aspirin Aspirin Chewable Low Dose Aspirin 325mg Aspirin Rapid Relief Circle K Headache Relief Extra Strength Entrophen Ect 975mg Nervine Regular Strength Aspirin EC Asaphen E.C. 80 mg Coachs First Aid Contains 102 Pieces ARC Emergency Preparedness FIRST AID Contains 202 PIECES Unishield Aspirin Acetylsalicylic Acid Tab 325mg Neo Tigol Tab Pain Aid Anacin Caplets CVS Health Extra Strength Antacid and Pain Reliever Novasen Drug Mart Effervescent Pain Relief Euro Asa 325mg Chewable Tablet Bc Acetylsalicylic Acid, Caffeine and 8 Mg Codeine Phosphate Aspirin 81mg Adult Low Dose Muscle & Back Pain Relief Extra Strength 4139 First Aid Kit Biovanta Trip Action Green Apple and Honey Orphengesic Forte Smart Sense Migraine Formula Green Guard Tri Buffered Aspirin relief Extra Strength Aspirin Backache Pain Free Plus Asa Tab 325mg Enteric Coated Extraprin Family Wellness Effervescent Cold Relief Orange TopCare Effervescent Antacid and Pain Relief Pain Relief Aspirin Chewable, Low Dose Acetylsalicylic Acid 325mg Tablets USP ACME FIRST AID Contains 404 PIECES Biovanta Trip Action Lemon and Honey Family Wellness Aspirin Sunmark aspirin low dose Good Neighbor Pharmacy Migraine Relief Fiorinal-C 1/2 Splizz Pain Reliever - Orange-flavored Up and Up aspirin Crane Safety XS Pain Relief Rivasa Fc Sunmark Aspirin Aspirin Low Dose Chewable Adventure Medical Kits 1-2 Person National Ski Patrol First Aid Enteric Coated Aspirin Regular Strength Vanquish Digital Headache Phenaphen No.3 Cap C-2 Buffered With Codeine Aspirin Regular Strength Regular Strength Acetylsalicylic Acid 325mg Tab Quality Choice Effervescent Cold Relief - Orange Adult Low Dose Aspirin Enteric Safety Coated Aspirin Alka-Seltzer Conney Aspirin Sunmark Adult Aspirin Aramark Aspirin Rivasa 81 Mg EC Aspirin enteric coated low dose Rapidol Aspirin Relief Asa Extra Strength Pain Relief Added Strength Aspirin NSAID Signature Care Effervescent Antacid and Pain Relief Freds Effervescent Antacid Pain Relief BioElectro Extra Strength Daytime Pain Relief ConRx pain Reliever 4313 First Aid Kit Good Sense Aspirin Enteric Safety Coated Only for Headache Alka-seltzer Morning Relief ASPIRIN Low Strength PMS-asa Valumeds Aspirin Exaprin Coraspirina 81 mg Tabletas con cubierta enterica Unishield Pain Zapper Entrophen 325mg Tablets Dr. Juans Santo Remedio PARA LA ACIDEZ Equate Effervescent Cold Relief 4346 First Aid Kit Walgreens Antacid Pain Relief Extra Strength Alka Seltzer Plus 2s Blister Pack Novo Ac and C 8mg Tab Aspirin Extra Strength Asa and Caffeine Smart Sense Aspirin Biovanta Double Action Extra Strength Headache ASPIRIN Regular Strength Percodan Astrin 5gr Adult Low Dose Enteric Coated Aspirin Methoxisal-C 1/4 Advanced Pain Reliever Aspirin Adult Low Strength Aspirin Acetaminophen, Aspirin and Codeine Phosphate Dye-Free Aspirin 81 Artrifin 24 Caplets MEDI-FIRST Tri Buffered Aspirin Trianal Capsules Bayer Womens Carisoprodol and Aspirin 4228 First Aid Kit Aspirin Plus Stomach Guard Ext.stgth.caplet Alka-Seltzer Plus Cold and Cough Formula Extra Pain Reliever Sound Body Migraine Relief Thompson XS Pain Ache Painex Tab 0.25gr Anacin AF PMS-pharnal Tablets HEB Extra Strength Effervescent Antacid and Pain Relief Dr Pausins Low Dose Aspirin Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy Goodys 25 Person ANSI Aspirin 81mg Quick Chews Alka-Seltzer Plus Severe Cold and Cough PowerFast Fizz Excedrin Back and Body Asa 325 Mg Tablets Regular Strength Dg Health Migraine Relief Asatab EC 650mg A.C. & C. 8mg Asaphen Formu Care pain reliever added strength Sunmark Aspirin Adult Low Strength Axisal-C1/8 Coryphen 650 Tab Aspirin Pain Relief Aspirin Safety Coated Enteric, Regular Strength Aspirin Low Dose Chewable Orange Goodys Back and Body Pain St. Joseph Chewable Low Dose Aspirin Family Care Effervescent Antacid and Pain Relief Up and Up Chewable Aspirin Aspirin-dipyridamole Rapid Comfort Aspirin Alka-Seltzer Original Flavor Bayer Plus Extra Strength Enteric coated aspirin Asatab 80 Mg Chewable Tablets Best Choice Effervescent Antacid Pain Relief Aspirin Coated for Delayed Release Extra Strength A & C Tablets With Codeine 15mg Alka Seltzer Evt Asa Extra Strength Tab 500mg Signature Care Aspririn Aspirin Thin coated Asa 80mg A.S.A. 80mg Acetylsalicylic Acid Tablets Coated Aspirin Unishield Pain Ache 4225 First Aid Kit Alka-Seltzer Plus Cold Night Health Sense Aspirin 81 BioElectro Day Chewable Low Dose Kroger Value Aspirin Berkley and Jensen Migraine Relief Durlaza Goodys Cool Orange Pain Reliever 2 Midol Regular CVS Health Medication and Topical Refill Pouch Robaxisal Caplets Health Sense Ecpirin Asa, Caffeine & 8mg Codeine Phosphate Alka-Seltzer Original Aspi-Cor Value Pharma Aspirin Pain Reliever Rugby Aspirin Taro-dipyridamole/ Asa 4032 First Aid Kit Alka-Seltzer Plus Multi-Symptom Cold Day and Night Pain Terminator 2 Severe Auto 157 Care One headache relief added strength Exact Coated Daily Low-dose Asa Bufferin Arthritis PHL-asa E.C. Aspirin Extra Strength 500mg Tab USP Aspirin Tab 325mg USP Muscle and Back Pain Relief Asasantine Cap EXTRA STRENGTH Headache Relief geltabs Halfprin Low Dose Aspirin Walgreens Effervescent Pain Relief Topcare Headache Formula Asa Chewable Tablets Coated Aspirin Low-dose PhysiciansCare Extra Stregth Pain Reliever
Indication	Pain, fever, and inflammation Acetylsalicylic acid (ASA), in the regular tablet form (immediate-release), is indicated to relieve pain, fever, and inflammation associated with many conditions, including the flu, the common cold, neck and back pain, dysmenorrhea, headache, tooth pain, sprains, fractures, myositis, neuralgia, synovitis, arthritis, bursitis, burns, and various injuries. It is also used for symptomatic pain relief after surgical and dental procedures [FDA label]. The _extra strength_ formulation of acetylsalicylic acid is also indicated for the management migraine pain with photophobia (sensitivity to light) and phonophobia (sensitivity to sound)[FDA label]. Other indications ASA is also indicated for various other purposes, due to its ability to inhibit platelet aggregation. These include: Reducing the risk of cardiovascular death in suspected cases of myocardial infarction (MI) [FDA label]. Reducing the risk of a first non-fatal myocardial infarction in patients, and for reducing the risk of morbidity and mortality in cases of unstable angina and in those who have had a prior myocardial infarction [FDA label]. For reducing the risk of transient ischemic attacks (TIA) and to prevent atherothrombotic cerebral infarction (in conjunction with other treatments) [FDA label]. For the prevention of thromboembolism after hip replacement surgery [FDA label]. For decreasing platelet to platelet adhesion following carotid endarterectomy, aiding in the prevention of transient ischemic attacks (TIA) [FDA label]. Used for patients undergoing hemodialysis with a silicone rubber arteriovenous cannula inserted to prevent thrombosis at the insertion site [FDA Label]. Important note regarding use of the extended-release formulation [F4405] In the setting of acute myocardial infarction, or before percutaneous interventions, the extended-release form of acetylsalicylic acid should not be used. Use immediate-release formulations in scenarios requiring rapid onset of action [Label, F4405]. The extended-release form is taken to decrease the incidence of mortality and myocardial infarction (MI) for individuals diagnosed with chronic coronary artery disease (CAD), including patients with previous myocardial infarction (MI) or unstable angina or with chronic stable angina. Additionally, the extended-release form is used to decrease the risk of death and recurrent episodes of stroke in patients with a history of stroke or TIA [F4405].
Categories	Acids, Carbocyclic Agents causing angioedema Agents causing hyperkalemia Agents that produce hypertension Alimentary Tract and Metabolism Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) Antiinflammatory and Antirheumatic Products Antiplatelet agents Antipyretics Benzene Derivatives Blood and Blood Forming Organs Cardiovascular Agents Cyclooxygenase Inhibitors Cytochrome P-450 CYP2C19 Inducers Cytochrome P-450 CYP2C19 Inducers (strength unknown) Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Substrates Decreased Platelet Aggregation Decreased Prostaglandin Production Drugs that are Mainly Renally Excreted Hematologic Agents Hydroxybenzoates Musculo-Skeletal System Nephrotoxic agents Non COX-2 selective NSAIDS OAT1/SLC22A6 inhibitors OAT3/SLC22A8 Inhibitors P-glycoprotein inducers P-glycoprotein substrates Peripheral Nervous System Agents Platelet Aggregation Inhibitors Excl. Heparin Salicylates Salicylic Acid and Derivatives Sensory System Agents Stomatological Preparations UGT1A6 substrate
ATC-Code	B01AC06 C07FX04 C10BX04 M01BA03 C10BX02 N02BA71 B01AC56 N02AJ07 N02AJ02 N02BA01 B01AF51 C10BX05 N02BA51 A01AD05 C10BX01 C07FX03 N02AJ18 C10BX12 C10BX08 C10BX06 C07FX02
CAS number	50-78-2

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Prostaglandin G/H synthase 1	MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFG...	unknown	inhibitor
3-hydroxy-3-methylglutaryl-coenzyme A reductase	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYEC...	unknown	inhibitor
Prostaglandin G/H synthase 2	MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFY...	unknown	inhibitor
Aldo-keto reductase family 1 member C1	MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHID...	unknown	inhibitor
5'-AMP-activated protein kinase	MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTG...	unknown	activator
Endothelin-1 receptor	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVT...	unknown	inhibitor
Cellular tumor antigen p53	MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDI...	unknown	inducer
Endoplasmic reticulum chaperone BiP	MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRV...	unknown	inhibitor,binder
Ribosomal protein S6 kinase alpha-3	MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEI...	unknown	inhibitor
NF-kappa-B inhibitor alpha	MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQ...	unknown	inhibitor
Tumor necrosis factor-inducible gene 6 protein	MIILIYLFLLLWEDTQGWGFKDGIFHNSIWLERAAGVYHREARSGKYKLT...	unknown	inhibitor,downregulator
Caspase-1	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATV...	unknown	inhibitor,downregulator
Caspase-3	MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIII...	unknown	inhibitor,downregulator
Inhibitor of nuclear factor kappa-B kinase subunit beta	MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQEL...	unknown
Extracellular signal-regulated kinase (ERK)	MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR...	unknown
G1/S-specific cyclin-D1	MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQK...	unknown	downregulator
Myc proto-oncogene protein	MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQ...	unknown	downregulator
Proliferating cell nuclear antigen	MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQL...	unknown	downregulator
Cyclin A	-	unknown	downregulator
Sialidase-1	MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAEND...	unknown	inhibitor
Cytochrome P450 2C19	MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDV...	unknown	inducer
Cytochrome P450 2C9	MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDI...	unknown	substrate
UDP-glucuronosyltransferase 1-6	MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLS...	unknown	substrate
Arylamine N-acetyltransferase 2	MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMEL...	unknown	substrate
Solute carrier family 22 member 6	MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCR...	unknown	inhibitor
ATP-dependent translocase ABCB1	MDLEGDRNGGAKKKNFFKLNNKSEKDKKEKKPTVSVFSMFRYSNWLDKLY...	unknown	substrate,inducer,modulator
Organic anion transporter 3	MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCR...	unknown	inhibitor
View More

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
Pharos	CHEMBL25
PubChem	2244
ChEMBL	CHEMBL25
ChEBI	CHEBI:15365
CCDC/CSD	ACSALA21, ACSALA23, ACSALA14, TAZRAO01, DIFQAK, ACSALA20, DIPJAQ, VUGMIT, ACSALA26, ACSALA15, ARIFOX, KEWNOQ, ACSALA17, ACSALA25, ACSALA01, ACSALA19, SIBYUA, ACSALA27, TAZRAO, HUNJEH, ACSALA28, SIBYUA01, ACSALA02, ACSALA08, ACSALA07, ACSALA05, ACSALA03, ACSALA04, ACSALA06, ACSALA11, ACSALA09, SIBYUA02, ACSALA29, GARYEH, HAPCOU
COD	7126911, 1515582, 1515581, 2104857, 1516479, 1516481, 1516480, 4100978, 7247818, 7247819, 7050897, 7050898, 7050899, 7050900, 7050901, 7050902, 7050903