C

CYTIDINE-5'-MONOPHOSPHATE

Created:	1999-07-08
Last modified:	2011-06-04

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11 entries where C is found as a standalone ligand3 entries where C is covalently linked to polymer or other heterogen groups 7,609 entries where C is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	35
Chiral Atom Count	4
Bond Count	36
Aromatic Bond Count	0

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Chemical Component Summary
Name	CYTIDINE-5'-MONOPHOSPHATE
Systematic Name (OpenEye OEToolkits)	[(2R,3S,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₉ H₁₄ N₃ O₈ P
Molecular Weight	323.197
Type	RNA LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C1N=C(N)C=CN1C2OC(C(O)C2O)COP(=O)(O)O
SMILES	CACTVS	3.341	NC1=NC(=O)N(C=C1)[CH]2O[CH](CO[P](O)(O)=O)[CH](O)[CH]2O
SMILES	OpenEye OEToolkits	1.5.0	C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O
Canonical SMILES	CACTVS	3.341	NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO[P](O)(O)=O)[C@@H](O)[C@H]2O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O
InChI	InChI	1.03	InChI=1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKey	InChI	1.03	IERHLVCPSMICTF-XVFCMESISA-N

Drug Info: DrugBank

DrugBank ID	DB03403
Name	Cytidine-5'-Monophosphate
Groups	experimental
Description	A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.
Synonyms	Cytidine monophosphate Cytidylic acid 5'-CMP Cytidine 5'-Monophosphate Disodium Salt Cytidine-5'-Monophosphate pC cytidylate CMP
Categories	Cytosine Nucleotides Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Pyrimidine Nucleotides Pyrimidines Ribonucleotides
CAS number	63-37-6

Drug Targets

Name	Target Sequence	Pharmacological Action
Uridine-cytidine kinase 2	MAGDSEQTLQNHQQPNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVD...	unknown
3-deoxy-manno-octulosonate cytidylyltransferase	MSKAVIVIPARYGSSRLPGKPLLDIVGKPMIQHVYERALQVAGVAEVWVA...	unknown
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLG...	unknown
Bifunctional enzyme IspD/IspF	MSEMSLIMLAAGNSTRFNTKVKKQFLRLGNDPLWLYATKNLSSFYPFKKI...	unknown
UMP-CMP kinase	MKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYG...	unknown
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	MRIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAALHALTDALLS...	unknown
Cytidylate kinase	MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHH...	unknown
Coenzyme A biosynthesis bifunctional protein CoaBC	MSLAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAKAFITPL...	unknown
Alpha-2,3-/2,8-sialyltransferase	MKKVIIAGNGPSLKEIDYSRLPNDFDVFRCNQFYFEDKYYLGKKCKAVFY...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682