Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to [Theophylline] and [Theobromine].[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in various teas and cacao beans, which are different than coffee beans.[T716] Caffeine is also used in a variety of cosmetic products and can be administered topically, orally, by inhalation, or by injection.[T716] The caffeine citrate injection, used for apnea of the premature newborn, was initially approved by the FDA in 1999.[L9863] According to an article from 2017, more than 15 million babies are born prematurely worldwide. This correlates to about 1 in 10 births. Premature birth can lead to apnea and bronchopulmonary dysplasia, a condition that interferes with lung development and may eventually cause asthma or early onset emphysema in those born prematurely.[A187694] Caffeine is beneficial in preventing and treating apnea and bronchopulmonary dysplasia in newborns, improving the quality of life of premature infants.[T716]
Synonyms
Caféine
Mateína
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
Koffein
Caffeinum
Theine
Thein
Anhydrous caffeine
1,3,7-trimethylpurine-2,6-dione
Coffein
Cafeína
1,3,7-trimethylxanthine
1-methyltheobromine
Teína
Guaranine
Caffeine
Methyltheobromine
Coffeinum
Caffeine citrate
7-methyltheophylline
1,3,7-trimethyl-2,6-dioxopurine
Brand Names
Pain Aid
BioElectro Extra Strength Daytime Pain Relief
Diurex Water Pills
Extra Strength Midol Relief
Adults Acetaminophen and Caffeine Pain Reliever Fever Reducer
Goodys Headache Relief Shot
Pain Stoppers Regular
Health Mart Stay Awake
Diurette Water Pills
Herbopyrine Tab 325mg
Tension Headache Aspirin Free
Kirkland Signature Migraine Headache Relief
Norgesic Forte
Pronal Capsules
GOODYS Extra Strength Headache Mixed Fruit Blast
Menstrual Pain Relief
Reese Headache Powders
Acetaminophen 500 Mg With 15 Mg Caffeine and 8 Mg Codeine Phosphate
Exdol 15tab
Pamprin Max Menstrual Pain Relief
FLO PMS Complete
BioElectro Day
Artrifin 24 Caplets
Excedrin Extra Strength Caplets
New Hanbang Col Cap
Corytab
Norgesic
4346 First Aid Kit
Healthy Accents migraine formula
Headache, Circle K
ShopRite Migraine Formula
Equaline migraine formula
Triatec Fort/strong Ultra Efficace/ultra Relief
Excedrin PM Triple Action Caplets and Excedrin Tension Headache
Powerbooster original
Dg Health Headache Relief
Butalbital, Acetaminophen and Caffeine
Anacin Extra Strength Tablet
Excedrin Extra Strength
Quality Choice Pain Relief Powder
Allertness Aid
Medi First Plus Pain Ache
Dolgic Plus
Cove Migraine Relief
Family Wellness Pain Relief Powder
Stanback
Butalbital, Acetaminophen, and Caffeine
Novo-gesic C15
Apo-acetaco #1
Diurex Water Pills XPL
Medique Pain Off
Blowfish
Acetaminophen Ultra Relief Extra Strength
Butalbital, Acetaminophen and Caffeine Plus
Pain Relief Extra Strength
Acetaminophen 500 Mg Compound Tablets With Codeine
Caffeine is indicated for the short term treatment of apnea of prematurity in infants and off label for the prevention and treatment of bronchopulmonary dysplasia caused by premature birth.[T716,L9851] In addition, it is indicated in combination with sodium benzoate to treat respiratory depression resulting from an overdose with CNS depressant drugs.[L9899] Caffeine has a broad range of over the counter uses, and is found in energy supplements, athletic enhancement products, pain relief products, as well as cosmetic products.[T716,L9854,L9872]
Categories
Alkaloids
Anorexigenic Agents & Respiratory and CNS Stimulants
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
