DrugBank ID DB00205 Name Pyrimethamine Groups approved vet_approved investigational Description One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis. Synonyms Pirimetamina Ethylpyrimidine Pyriméthamine CD Pyrimethaminum
5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine Pyrimethamine Chloridyn 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine Pyrimethamine hydrochloride Diaminopyritamin 2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine 5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine 2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine Primethamine Chloridine more Brand Names Pyrimethamine Daraprim Fansidar Fansidar Tablets Pyrimethamine Leucovorin Indication For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine Categories Anti-Infective Agents Antibiotics for Pneumocystis Pneumonia Antimalarial diaminopyrimidines Antimalarials Antiparasitic Agents
Antiparasitic Products, Insecticides and Repellents Antiprotozoals Cytochrome P-450 CYP2C8 Inhibitors Cytochrome P-450 CYP2C8 Inhibitors (weak) Cytochrome P-450 Enzyme Inhibitors Enzyme Inhibitors Folic Acid Antagonists MATE 1 Inhibitors MATE 2 Inhibitors MATE inhibitors Pyrimidines more ATC-Code P01BF09 P01BD01 P01BD51 P01BF04 CAS number 58-14-0 
