DG

2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE

Created: 2001-06-01
Last modified:  2024-09-27

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Chemical Details

Formal Charge0
Atom Count37
Chiral Atom Count3
Bond Count39
Aromatic Bond Count5
2D diagram of DG
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Chemical Component Summary

Name2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE
Systematic Name (OpenEye OEToolkits)[(2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-oxolan-2-yl]methyl dihydrogen phosphate
FormulaC10 H14 N5 O7 P
Molecular Weight347.221
TypeDNA LINKING

Chemical Descriptors

TypeProgram Version Descriptor
SMILESACDLabs10.04O=C1c2ncn(c2N=C(N)N1)C3OC(C(O)C3)COP(=O)(O)O
SMILESCACTVS3.341NC1=Nc2n(cnc2C(=O)N1)[CH]3C[CH](O)[CH](CO[P](O)(O)=O)O3
SMILESOpenEye OEToolkits1.5.0c1nc2c(n1C3CC(C(O3)COP(=O)(O)O)O)N=C(NC2=O)N
Canonical SMILESCACTVS3.341 NC1=Nc2n(cnc2C(=O)N1)[C@H]3C[C@H](O)[C@@H](CO[P](O)(O)=O)O3
Canonical SMILESOpenEye OEToolkits1.5.0 c1nc2c(n1[C@H]3C[C@@H]([C@H](O3)COP(=O)(O)O)O)N=C(NC2=O)N
InChIInChI1.03 InChI=1S/C10H14N5O7P/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1
InChIKeyInChI1.03 LTFMZDNNPPEQNG-KVQBGUIXSA-N

Drug Info: DrugBank

DrugBank IDDB04457 
Name2'-Deoxyguanosine-5'-Monophosphate
Groups experimental
Synonyms2'-Deoxyguanosine-5'-Monophosphate
CAS number902-04-5

Drug Targets

NameTarget SequencePharmacological ActionActions
Thymidylate synthaseMKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRC...unknown
Deoxynucleotide monophosphate kinaseMKLIFLSGVKRSGKDTTADFIMSNYSAVKYQLAGPIKDALAYAWGVFAAN...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 65059, 5280340, 135398597
ChEMBL CHEMBL477487
ChEBI CHEBI:16192