DTU

(2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL

Created:	2004-06-18
Last modified:	2024-09-27

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34 entries where DTU is found as a standalone ligand9 entries where DTU is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	18
Chiral Atom Count	2
Bond Count	17
Aromatic Bond Count	0

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Chemical Component Summary
Name	(2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL
Systematic Name (OpenEye OEToolkits)	(2S,3R)-1,4-bis-sulfanylbutane-2,3-diol
Formula	C₄ H₁₀ O₂ S₂
Molecular Weight	154.251
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	SCC(O)C(O)CS
SMILES	CACTVS	3.341	O[CH](CS)[CH](O)CS
SMILES	OpenEye OEToolkits	1.5.0	C(C(C(CS)O)O)S
Canonical SMILES	CACTVS	3.341	O[C@H](CS)[C@@H](O)CS
Canonical SMILES	OpenEye OEToolkits	1.5.0	C([C@H]([C@H](CS)O)O)S
InChI	InChI	1.03	InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+
InChIKey	InChI	1.03	VHJLVAABSRFDPM-ZXZARUISSA-N

Drug Info: DrugBank

DrugBank ID	DB01692
Name	Dithioerythritol
Groups	experimental
Description	A compound that, along with its isomer, Cleland's reagent (dithiothreitol), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl groups. [PubChem]
Synonyms	1,4-dithioerythritol (2R,3S)-1,4-dimercaptobutane-2,3-diol erythro-1,4-Dimercapto-2,3-butanediol Dithioerythritol (2R,3S)-1,4-dimercapto-2,3-butanediol DTE
Categories	Alcohols Carbohydrates Compounds used in a research, industrial, or household setting Indicators and Reagents Laboratory Chemicals Sugar Alcohols Sulfhydryl Reagents Sulfur Compounds Thioglycosides
CAS number	6892-68-8

Drug Targets

Name	Target Sequence	Pharmacological Action
Listeriolysin regulatory protein	MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTS...	unknown
6,7-dimethyl-8-ribityllumazine synthase	MKGGAGVPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDD...	unknown
Thymidine kinase, cytosolic	MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKC...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682