EDR

EDROPHONIUM ION

Created:1999-07-08
Last modified:  2011-06-04

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Chemical Details

Formal Charge1
Atom Count28
Chiral Atom Count0
Bond Count28
Aromatic Bond Count6
2D diagram of EDR
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Chemical Component Summary

NameEDROPHONIUM ION
Systematic Name (OpenEye OEToolkits)ethyl-(3-hydroxyphenyl)-dimethyl-azanium
FormulaC10 H16 N O
Molecular Weight166.24
TypeNON-POLYMER

Chemical Descriptors

TypeProgramVersionDescriptor
SMILESACDLabs10.04Oc1cccc(c1)[N+](C)(CC)C
SMILESCACTVS3.341CC[N+](C)(C)c1cccc(O)c1
SMILESOpenEye OEToolkits1.5.0CC[N+](C)(C)c1cccc(c1)O
Canonical SMILESCACTVS3.341 CC[N+](C)(C)c1cccc(O)c1
Canonical SMILESOpenEye OEToolkits1.5.0 CC[N+](C)(C)c1cccc(c1)O
InChIInChI1.03 InChI=1S/C10H15NO/c1-4-11(2,3)9-6-5-7-10(12)8-9/h5-8H,4H2,1-3H3/p+1
InChIKeyInChI1.03 VWLHWLSRQJQWRG-UHFFFAOYSA-O

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License
DrugBank IDDB01010 
NameEdrophonium
Groups approved
DescriptionA rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Synonyms
  • Edrophonium chloride
  • Edrophonium ion
  • N-ethyl-3-hydroxy-N,N-dimethylanilinium
  • Edrophonium cation
  • Ethyl-(3-hydroxy-phenyl)-dimethyl-ammonium
Brand Names
  • Enlon-Plus
  • Enlon 10mg/ml
  • Enlon Liq IV 10mg/ml
  • Tensilon
  • Enlon Plus
IndicationFor the differential diagnosis of myasthenia gravis and as an adjunct in the evaluation of treatment requirements in this disease. It may also be used for evaluating emergency treatment in myasthenic crises.
Categories
  • Amines
  • Antidotes
  • Cholinergic Agents
  • Cholinesterase Inhibitors
  • Compounds used in a research, industrial, or household setting
ATC-CodeV04CX07
CAS number312-48-1

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License
NameTarget SequencePharmacological ActionActions
CholinesteraseMHSKVTIICIRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFG...unknowninhibitor
AcetylcholinesteraseMRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRG...unknowninhibitor
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 3202
ChEMBL CHEMBL1104
ChEBI CHEBI:251408