DrugBank ID DB00281 Name Lidocaine Groups vet_approved approved investigational Description Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication [T583]. In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical procedures [F4349, L5930, L5948]. It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues that have the medication applied on are transiently incapable of signaling the brain regarding sensations [F4349, L5930, L5948]. In doing so, however, it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and irregular heart rate, among others [F4349, L5930, L5948]. As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. Nevertheless, lidocaine's local anesthetic action sees its use in many medical situations or circumstances that may benefit from its action, including the treatment of premature ejaculation [A177625]. Regardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis. It is even included in the World Health Organization's List of Essential Medicines [L6055]. Synonyms lidocaïne Lidocaine hydrochloride anhydrous Lidocaine Lidocaine hydrochloride Lidocainum
Lidocaina Lidocaína 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide 2-(Diethylamino)-2',6'-acetoxylidide alpha-diethylamino-2,6-dimethylacetanilide α-diethylamino-2,6-dimethylacetanilide Lignocaine more Brand Names AnaMantle HC DermaNumb Tattoo Anesthetic Pain and Itch Relief 4% Lidocaine Thera Care Pain Therapy Uber Numb
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Preparedness Contains 167 PIECES Sera Relief Ultimate Rapid Soothing Creme Lidocaine Pain Relief with Lavender Renuu Patch Bactine Original First Aid Coralite Lidocaine Pain Relief Point Relief LidoSpot 4 Lidocaine Topical Anesthetic After Sun Gel Leader PAIN RELIEF PATCHES K40-lido SCLERA CARE Topical Anesthetic Gel Tribioticlc Lc Lc CBDMEDIC Itch and Rash 4337 First Aid Kit 4290 First Aid Kit Hempvana Ultra Strength Pain Relief Cream Polysporin Burn Formula Cream ReCellTis SYREN Intimate Relief Topical Pain Relief Jelido 4237 First Aid Kit Tridacaine III Advanced DNA Medicated Collection Kit II AsperFlex NUMB PLUS Maximum Strength Anorectal 5% Xylocaine Mpf With Glucose 7.5% Injection Regenecare Ha Harmony Hemp NeuroComfort 4% Lidocaine Pain Relief 1000mg ABSORBINE jr. Pliaglis ReadySharp-K Syntherma Plus Xylonor Gel Bus and Classroom Yellow 4166 First Aid Kit First Aid and Burn Lignospan Standard Lidomyxin 4312 First Aid Kit Zionodil External Lidolog Kit Fsk-5 4277 First Aid Kit PAIN RELIEF Gel-Patch Ketorocaine L Kit Lidopril Numbify Tropical Gold Atozcup Tattoo Numbing Aramark Star Burn Gel Extra Strength Scar Prevention 4400 First Aid Kit Forticept Wounds and Burns Hydrogel Anestafoam Antibiotic Cream Plus Pain Relief for Kids 4239 First Aid Kit Aloe Burn Relief Extra Strength Liquid Burn Relief Gel American Safety First Aid 4275 First Aid Kit 4227 First Aid Kit Mld KAISASA Tattoo Numbing Limencin Bed Bug Instant Bite Relief Panama Jack Burn Relief Gel with Lidocaine Emla Patch Kroger Aloe Vera Pain Relieving LidoRxKit Beta Inject Kit Xylocaine Mpf 1% PMS-lidocaine Viscous 2% The Davinci Company Medline 4247 First Aid Kit Lidocaine and Tetracaine Deeveeant Numb Salonpas LIDOCAINE PLUS Neurozyl 4194 First Aid Kit Kroger Pain Relief Lidocaine Patch Numbify sanitize Itch relief Cream Redicare Blood Clotting Octocaine 50 4200 First Aid Kit DermaNumb Analgesic NOpiod-TC PainBloc24 Flexi-Stretch Pain Tape COOL CURE Pain Relief Mega Patch Diclona Patch Mlc Zone 2 Blt 2 DOCTORS TOUCH Erase The Pain Lidocaine Sx1 Medicated Post-Operative System Alocane On The Go LIDOCAINE HCl and EPINEPHRINE OKeeffes Healthy Feet Tucks Multi-Care Relief Kit (Tucks Hemorrhoidal and Tucks Medicated Cooling 40 Count) Solmate Burn Relief Gel Good Sense endure First Aid Kit 64058024 Swabplus Piercing Care Swabs TopCare Pain Relief Patch 4269 First Aid Kit 4291 First Aid Kit Dynamo Delay Sample Bottle Careland Lidocaine 4 plus menthol pain relieving gel-patches with border for knee Meijer Cold and Hot Pain Relieving Analgesic Burn with Lidocaine Meijer Lidocaine Pain Relief Patch Assortment Small Redicare Burn Gel Salonpas Pain Relieving Cream Exsel Aloe Derma Gel Relief Dr. Scholl's Cracked Heel Relief Cream Harmony Hemp NeuroComfort 4% Lidocaine Pain Relief 500mg 4171 First Aid Kit UniShield First Aid Burn 4313 First Aid Kit Lido GB-300 LidoCream 4 4191 First Aid Kit Pain Relief Rite Aid Coralite Odor Free Pain Relief First Aid Triple Antibiotic with Pain Reliever Lidocan V Aloe Ice Sunburn Relief Mericaine Lidocaine Hydrochloride and Epinephrine Bitartrate Lidocaine Hydrochloride Injection Central Venous Catetherization Kit Point Of Care L2 LidoFore 4% FlexiPatch No-AD Aloe Vera Gel 98% Pure ABREVA Rapid Pain Relief Neolinn SWISS NAVY Endurance Rx LidoMet-10 Kit Dibucaine HCl 0.5% / Lidocaine 15% / Phenylephrine HCl 1% / Prilocaine 5% Vonaflex curacaine Transdermal Corporation Aspercreme with Lidocaine Numbify Smooth Disposable Convenience Kit (Single Shot Epidural) SkyaDerm-LP Lido-RX 4.1 Kroger Burn Relief Aloe Fonow Insta Relief DM Care Bus and Classroom Yellow Doctor Butlers Hemorrhoid and Fissure External Pain Formula 4121 First Aid Kit LIDOCAINE HCl AND EPINEPHRINE North Burn Relief Predator Curist Hemorrhoid Relief Albertsons Pain Relief Patch Zilactin-L Early Relief Cold Sore Liquid Lidocaine 23% / Tetracaine 7% 4134 First Aid Kit Band-Aid Brand Hurt-Free Antiseptic Pain Relieving Anodyne Ile Jampocaine 2% Viscous Solution Warrior Rectal Care Xpect Burn Care 4156 First Aid Kit Basic Care Lidocaine Prolayed CVS Cold and Hot Polysporin Cold Sore Ointment Antibiotic Cream for Kids Electrum Numb Foam Prilopentin LidoPure Patch Albertson Lidocaine, Menthol Pain Relief Medicated Patch Xylocaine 2% W Epinephrine 1:200000 Walgreens 24-Hour Lidocaine Patch Lidocan Family Medic First-aid Treatment Lotion 3 Step First Aid Kit Numb Gel Anesthetic 4249 First Aid Kit 4117 First Aid Kit Soundbody TopCare Pain Relief Maximum Strength Tylenol Precise Cooling Pain Relieving Natureplex Lidocaine 4% Aromalief Lidocaine Roll On Planticin Advanced Topical Pain Relief Sheffield Lidocaine 4049 First Aid Kit Bruselix Cream Meijer Pain Relief Pantin PM External LidoPatch Pain Relief Pain Relief Roll-on Good Sense eLenza Patch Botanika Life Ultra-Relief Pain Rub Unburn-gel 2.5% Xylocaine 5% Spinal Zee First Aid Cream MenthoReal-10 Kit CVS Health Lidocaine Pain Relief Ori-power Alcoholada Gel Pain Relieving Pain 4116 First Aid Kit Extra Strength Postherpetic Neuralgia Lidocaine 5% Gel CVS First Aid Kit Scar Patch Gen7T Plus Target Up and Up After Sun Cooling Arthrogram Tray 1% LevigoLT Lidoxryl NOpioid-LMC Lidocaine Patch Burn Ease, 3.5g Hustle Helper Curist Lidocaine Relief Relyyks 4149 First Aid Kit Lumbar Puncture Tray 1% Pediatric/infant Lidocaine HCl 3% and Hydrocortisone Acetate1% Cream 4323 First Aid Kit 4251 First Aid Kit 4360 First Aid Kit Leader Permavan External Patch Antibiotic Plus Pain Relief Cream Maximun Strength Lidocaine Patch Plus Menthol Lidocaine Hydrochloride and Epinephrine Injection USP Pro Plus 4067 First Aid Kit Lignospan Forte I.C.E. Lidocaine Gel - Gel Lidocaine Lidocore Lorenza Pain Relief Patch Zylotrol DyNAmic Plus Pak Kit Burn Mist Dyural 80 LM-C HealthWise Lidocaine Pain relief 4086 First Aid Kit Rite Aid Lidocaine Roll on QC Cool and Heat Roll-On Sonacaine Topical Anesthetic With Menthol Neosporin Plus Lidocaine Satohap Lidocaine 4% Menthol 1% Pain Relieving Cream Epidural Anesthesia Tray 4129 First Aid Kit Painless Tattoo 2 Prizotral II Mcl Lidonexe K-Mart SmartSense First Aid Contains 101 Pieces Medi-derm / L With Lidocaine Rx Satohap Lidocaine Hydrochloride 4 Percent Pain Relieving POWERECT Max Power Male Delay LidoFLEX Elbow, Single Pouch Equate Pain Relieving Patches Dr. Richs Numbing Octocaine HCl 2% Epinephrine 1:50000 LevigoSP Meijer Analgesic Lidocaine Topical Analgesic Ocean Breeze Pain Relief Ear Pain MD (E007) Lidocaine 4 Percent PLUS First Aid Value Pack - 77 Pieces Odynia-R Regular Intimale Lidocaine Delay Aspercreme with Lidocaine No-Mess Applicator Venipuncture CPI 4193 First Aid Kit 4140 First Aid Kit Alocane Severe Sunburn First Aid Burn Cream Single-shot Epidural Anesthesia Tray Alivio Jamshidi Bone Marrow Biopsy Tray Walgreen Maximum strength pain relieving cleansing Nuvakaan II NeuroMed Topical Anesthetic 7 DermaNumb Tattoo Anesthetic Gel Lidovex Performance Brands Steel Releaf Pain Relieving Liquid Naturally HL Extra Strength Insect Bite Numbing 4111 First Aid Kit Lidocare Arm, Neck, Leg Universal PAIN RELIEF Green Guard Super Stat Blood Clotting First Aid Lidothol Derma Numb Hempvana Knee Bird Ultra Strength Pain Relief Mentholix Pain Relief Equate Tridacaine II Wegmans Aloe After Sun Gel with Lidocaine HCl External Analgesic 4252 First Aid Kit Octocaine HCl 2% Epinephrine 1:100000 Base Laboratories Lidocaine Anesthetic Pain Relief AsperFlex MAX Spinal Anaesthesia Tray First Aid Antiseptic Well at Walgreens 4336 First Aid Kit Moshe Numbing Hemorrhoidal Lidotral 5% Gel Hawaiian Tropic After Sun Après Soleil Sunburn Relief Soulagement Des Coups De Soleil Lidocaine Maximum Strength Niravi 24 Hours Lidocaine 4 % Patch Refill 3 Aerowound Blood Clotting First Aid Sting Relief Pad DermacinRx Cinlone-I CPI P-Care K80MX Rugby Lidocaine Mueller First Aid Antiseptic LiProZonePak 4334 First Aid Kit Lidocaine Anesthetic Cream After Bite Wipe 4050 First Aid Kit Natural Seal Itch Relief for Kids Regenecare Hydrogel 4184 First Aid Kit Good Sense Burn Relief Aloe Hemorrhoid Pain Relief 4113 First Aid Kit Banana Boat Soothacaine Spray Gel Sun Burn Relief Cream Lidocaine Pain Relief Spray 4% Ebsl-5 MAKESENSE First Aid Myelogram Tray 1% Cold and Heat Lidocaine Patch Plus Menthol Soothee Patch Bite and Sting Relief Wipe Pain Relieving Cleansing Lubricaine 5 Lidocaine4 Lt Walgreens Burn relief CVS Bacitracin with Pain Relief Mlp A-2 Betalido Kit 4236 First Aid Kit Acme Home/Office/Auto Kit Xylocaine 1% Cacitrix Anorectal ECOLAB Burn TLC Plus Anesthetic S 4271 First Aid Kit PRILOVIX Plus Burn Relief Leader Icy Hot with Lidocaine No-Mess Itch Relief Max Strength Burn Relief Max Strength Yowch Extra Strength for minor burns Lidocaine with Menthol Patch Pain Releif Xylocaine 0.5% W Epinephrine 1:100000 CANNA NUMB Roll On BENGAY Ginger Citrus CVS Health Maximum Strength Lidocaine Pain Relief Cream Plus Menthol Lidocaine Pain Relief Sore Relief Hot and Cold Lidocaine with Menthol Patch Pain Relief Ear Pain MD for Kids Dbk Xylocard One Gm Additive Unit 20% Inj Tidl Pain Relief Massaging Roll-ON 4131 First Aid Kit General Numb Walg Aftrsn Burn Relief Meijer Pain Relief Patches Lidocaine Hydrochloride and Epinephrine 0.4% Lidocaine Hydrochloride and 5% Dextrose Injection VIVA Patch After Sun Soothing Spray Aspercreme Priloxx LP External Kit Microcaine Topical Analgesic Lidocaine HCl 0.8% and 5% Dextrose Inj myDerm Numbing Roll-On Walgreens Cooling DAYMARK FAK-35 First Aid Vpmax Cool N Heat Lidocaine Dry MyDerm Menthocin Patch with Lidocaine Flanax Back Pain Relief Quality Choice Pain Relief Patches Mamisan Pain Relieving Cream Lidocaine Plus Menthol DermacinRx Empricaine Lidozen Gel Chi-Myst Resolve Topical Yowch for minor burns by Pain Balm 4172 First Aid Kit more Indication Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks [F4349, L5930]. Categories Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use Agents that reduce seizure threshold Amides Amines Analgesics and Anesthetics
Anesthetics Anesthetics for Topical Use Anesthetics, Local Anilides Aniline Compounds Antiarrhythmic agents Antiarrhythmics, Class I Antiarrhythmics, Class Ib Antipruritics and Local Anesthetics Antipruritics, Incl. Antihistamines, Anesthetics, Etc. Cardiac Therapy Cardiovascular Agents Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (moderate) Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2A6 Substrates Cytochrome P-450 CYP2B6 Substrates Cytochrome P-450 CYP2C18 Substrates Cytochrome P-450 CYP2C8 Substrates Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Substrates Cytochrome P-450 CYP3A7 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dermatologicals Local Anesthesia Local Anesthetics (Amide) Membrane Transport Modulators Methemoglobinemia Associated Agents Nervous System Neuraxial Anesthetics Ophthalmologicals Otologicals P-glycoprotein inhibitors Peripheral Nervous System Agents Sensory System Agents Sodium Channel Blockers Throat Preparations Vasoprotectives Voltage-Gated Sodium Channel Blockers more ATC-Code S01HA07 D04AB01 R02AD02 C01BB01 S02DA01
N01BB52 C05AD01 N01BB02 more CAS number 137-58-6 
