DrugBank ID DB00281 Name Lidocaine Groups Description Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication [T583]. In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical procedures [F4349, L5930, L5948]. It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues that have the medication applied on are transiently incapable of signaling the brain regarding sensations [F4349, L5930, L5948]. In doing so, however, it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and irregular heart rate, among others [F4349, L5930, L5948]. As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. Nevertheless, lidocaine's local anesthetic action sees its use in many medical situations or circumstances that may benefit from its action, including the treatment of premature ejaculation [A177625]. Regardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis. It is even included in the World Health Organization's List of Essential Medicines [L6055]. Synonyms 2-(Diethylamino)-2',6'-acetoxylidide Lidocaine hydrochloride Lidocainum Lignocaine 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
Lidocaine hydrochloride anhydrous α-diethylamino-2,6-dimethylacetanilide Lidocaine Lidocaina Lidocaína alpha-diethylamino-2,6-dimethylacetanilide more Brand Names Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% Harmony Products LLC. General Numb 4327 First Aid Kit CVS Health All Purpose Kit
Assured Bikini Smooth Cream CYHOT Cream with Lidocaine Well at WAlgreens Akten Will Relieve Roll-On After Cuts and Scrapes OKeeffes Healthy Feet Pain Relief Cream Percutaneous Sheath Introducer Kit Hl-09883 Pacing Catheter Introducer Kit Acp-001px X3 On The Go First Aid Bite Relief Spray Lidocaine HCl Injection USP 1% (50mg/5ml) CALEXOTICS Fuck Sauce Anal First Aid Burn Cream After Sun Soothing Spray Extra Strength Foot Care Liquid Gel 4189 First Aid Kit JO for Him Prolonger with Lidocaine Icy Hot Lidocaine Pain Relieving Cream Plus Menthol Safetec Burn Gel CBD PAIN RELIEF Cream Miami Beach Burn Relief Arrow Two-lumen Jugular Catheterization Kit Lidodose 4338 First Aid Kit Neutrogena Anti-itch Moisturizer Satohap Lidocaine 4% Menthol 1% Pain Relieving Cream Lidocaine and Prilocaine 4199 First Aid Kit Rite Aid Pain Relief Cream 4050 First Aid Kit Diclona Gel Xylocaine 2% With Epinephrine 1:200000 Moxicaine kit Lidocaine 0.2% In 5% Dextrose Inj Cbd4 Freeze Pump Vanishing Scent 4056 First Aid Kit Ozonol Antibiotic Plus - Ointment Braline Patch Multi-lumen Central Venous Cathet Kit Venipuncture CPI 4220 First Aid Kit Spinal Anesthesia Tray Lidocaine HCl Inj 10mg/ml USP Inflammation Reduction Pack Solarcaine First Aid Lidocaine Spray Lidozen Patch Neurozyl Numbify Tropical Gold CBD MIST Topical Anesthetic Marbeta L Kit Prolayed Lidozion 4286 First Aid Kit Max 4 Men - Max Control Male Sex Prolong Unscented 4342 First Aid Kit 4157 First Aid Kit Curist Lidocaine Numbing Relief Numb 100 PRILOVIX UltraLite 4312 First Aid Kit LidoHeal-90 Lidolog Kit Just Cbd Relief Soothing Hemorrhoid Relief Cream Electrum Numb Anesthetic Zilacaine Patch Dragon Pain Numbing Roll-On Aramark Burn Cream HUSH Fast Acting Topical Anesthetic 4291 First Aid Kit NORTH Antiseptic First Aid Polysporin Complete LifeStyles EPIC Male Genital Desensitizer Ritual Tattoo ENDURE Male Genital Desensitizing Nuvakaan Sj3 Arrow Central Venous Catheterization Kit HemRid Anorectal Cream Steady Freddy Fruit of the Earth Aloe Vera Cool Blue Inderma MD Topicaine 5 Lidosporin Cream Zylotrol Pain Relieving Burn Relief Gel With Lidocaine 4320 First Aid Kit Zovacil 5 BLT-25 Kit Redicare Burn Gel Numb Soothe Lidocore Silvera Pain Relief Patch Topcare Pain Relief Patches Walgreens pain relieving Xesso Strawberry Rear Comfort Glide 4% Lidocaine ECOLAB Burn Cream Cml Elemar Patch EmReal Trifena 4186 First Aid Kit Dyural 40 Kit Lidocaine 30% 4252 First Aid Kit 4224 First Aid Kit Meijer Cold and Hot Pain Relieving Analgesic Antiseptic PRILOVIXIL Plus Lido Rx MTX Topical Pain 4359 First Aid Kit CVS Maximum Strength LIDOCAINE PLUS Advanced DNA Medicated Collection Kit II Crane Safety Burn Easy Care First Aid - 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Lidocaine Gel - Gel Lidocaine 4208 First Aid Kit Tiger delayspray Aloe Gel Pain Reliever Well at Walgreens Hot and Cold with Lidocaine Pain Relieving Vallement Flex Warrior Burn Relief Aloe Maximum Strength Xylocaine Mpf 1.5% With Epinephrine DCH Pain Relief Roll-On Alivio First Aid Antiseptic Swabs Prikaan Lite Relador Pak Plus Burn ReliefRelief H2Ocean Nothing Tattoo Glide And Soothing Balm Topicaine DCH Numbing Relief 4344 First Aid Kit Care Bus and Classroom Yellow Extra Strength Pruritis Care Burn First Aid Lidosync DX1 OraGenomic Medicated DNA Collection Screen TheraCare Pain Relieving Patch with Lidocaine QC Burn Relief Aloe EZ-Relief ReadySharp Anesthetics plus MethylPrednisolone 80 DermacinRx PHN Pak DG Health Maximum Strength Pain Relieving Cleansing 4048 Fist Aid Kit Medi-First Plus Burn with Lidocaine Lido-RX 4.1 Pain Relieving Gel-Patch PRILOVIX Plus Venipuncture Px1 4082 First Aid Kit Prolida Prilopentin -II Bikini Zone Zylotrol Plus Unburn-gel 2.5% Keepan A JOINT AND MUSCLE RELIEF 450 mg Equate After Sun Gel With Lidocaine Trubrexa Patch ER Lidocaine Anorectal P-Care K40MX Truu Balance Pain Relief Watkins Burn Cream Soulus Rp Rash and Pain POWERECT Lidocaine Male Delay 4305 First Aid Kit Pro-C-Dure 1 Kit Polysporin Cold Sore Ointment LidoCream 10 Afassco First Aid Burn Cream RECOVERY Numbing Xylocaine 2% Epidural Curist Hemorrhoid Relief Lidocaine Hydrochloride - Hydrocortisone Acetate TriXylitral Octocaine HCl 2% Epinephrine 1:50000 Ear Pain MD JTT Physicians Joint, Tunnel and Trigger Aspercreme with Lidocaine No-Mess Applicator Walgreens Lidocaine Plus Cream Meijer Lidocaine Pain Relief Patch Assortment Small 0.4% Lidocaine Hydrochloride and 5% Dextrose Injection 4173 First Aid Kit Lipovite 4051 First Aid Kit Blue Tube Emla Patch Mlp A-1 Minnerva II Pre-wax Pain Relief Aloe Ice Sunburn Relief Jelly Extra Strength Liquid Hemorrhoid Relief Gel Astero Biotic-Plus 4223 First Aid Kit Lidocaine Pain Relief 4163 First Aid Kit 4187 First Aid Kit Your Label Here Blood Clotting First Aid NeuroMed AR First Aid Spray Planticin Advanced Topical Pain Relief Re-Lieved Lidocaine Patch FIRST AID Contains 202 PIECES 4248 First Aid Kit Xylocaine 0.5% Lidocaine Hydrochloride Viscous Leximenth CBDMEDIC Itch and Rash Banana Boat Soothacaine Spray Gel Tribioticlc Lc Lc 4322 First Aid Kit 4266 First Aid Kit CVS Health Antibiotic Free Wound and Pain Relief 4206 First Aid Kit ScleraCare Lidocaine HCL PS-3885 Burn Ease, 3.5g 4269 First Aid Kit Lidopin Livixil Pak Satohap Lidocaine 4% Pain Relieving Pad Iwk-5 SECONDARY NUMB Lidocaine Phenylephrine Gel Hemorrhoid Relief Neurcaine Fonow Pain Prescriptives 5 Percutaneous Sheath Introducer Tray 4256 First Aid Kit DermacinRx Cinlone-I CPI XYLOCAIN (LIDOCAINE HCl ) Bite and Sting Relief Wipe 4171 First Aid Kit NULIDO Lidocaine Patch Plus Menthol Reg Bactine First Aid Spray 4198 First Aid Kit Predator Good Neighbor Pharmacy Aloe Vera Lidoxryl 4118 First Aid Kit H-Paxin Lidozo Topical Pain Patch Hemorrhoidal-Ointment Equate Pain Relieving Patches CVS Cold and Hot Centipaine for Pain Control LidoFLEX Elbow, Single Pouch Recticare Hemorrhoid Master Numbing Max Strength 4235 First Aid Kit TLC Plus Anesthetic G Priloxx LP External Kit Yowch extra strength for insect bites and stings Exchange Select Burn Relief Pain Relieving Quality Choice Pain Relief Patches Analgesic Tylenol Precise Pain Relieving 4273 First Aid Kit Good Sense endure Extra Strength Naturally Hl Itch Relief Super-Stop BloodClotter Amniocentesis Tray 1% ACME Small Cuts and Burns Gabacaine Siterol Base Laboratories Lidocaine Anesthetic Pain Relief P-Care K80MX After Burn Genuine First Aid Burn BAKERS BEST Pain Relief with Pure Hemp Seed Oil 4299 First Aid Kit Comfortox Lidocaine Lidocaine HCl Jelly 2% Pharmassist Soothenel Gel Elite Hyaluronic Acid 60mg and Lidocaine 2% PF Walgreens 24-Hour Lidocaine Patch Icy Hot with Lidocaine Pain Relieving Mericaine Lidosol Everyday Medical Everyday Numb Topical Anesthetic Cream Aspercreme with Lidocaine Lidocaine HCl Topical Solution Lidocaine Pain Relieving Lidotral I Otizol HC Liq Numbify Sanitize Lidocaine Hydrochloride Solution 4259 First Aid Kit Pain Relief Body Audacious Wreck Relief 4236 First Aid Kit Pain free IV 4064 First Aid Kit Maximum Strength Cold and Hot CVS Pain Relief 4% Lidocaine ABREVA Rapid Pain Relief Natural Seal Itch Relief for Kids Lidocaine-Prilocaine-Cream Base Rite Aid Rectal Care 4116 First Aid Kit Lido-mp40 4255 First Aid Kit HemAway DCH Hemorrhoidal Hot and Cold with Lidocaine-Careone Pain Relieving Lipritin II 4261 First Aid Kit 4282 First Aid Kit Insta Relief DM Derma Numb Recticare Advanced Dermalid DermacinRx Cinlone-II CPI 4085 First Aid Kit Wound Debridement Kit DermacinRx Lido V Pak Medi-sulting Topical Pain Relief Transderm-iQ Xylocaine 2% W Epinephrine 1:100000 4313 First Aid Kit Pain Relief Roll-ON Blood Clotting First Aid 4184 First Aid Kit Central Vein Catheterization Kit AnodyneRx Dermazyl Lidocan VII ASTONEA Burn Cream 4138 First Aid Kit Blackwork Restoriden Lidocaine Cream First Aid Only Burn Aramark Blood Clotting Diclocaine Comfort EZ Extra Strength Pain Relief Patch FourPainRX Bactine Pain Relieving 4047 Fist Aid Kit Fast Freeze Lidocaine Roll-On AOBBIY Tattoo Numbing Cream Lcm Alocane Med Numb 4049 First Aid Kit Lidomyxin 4068 First Aid Kit AUVON LIDOCAINE MENTHOL Pain Relief ACT Kit (Accelerated COVID-19 Test Kit) Zone 2 Poly-Prep ReadySharp Anesthetics plus Dexamethasone Sore relief First Aid GNP Icy Hot Lidocaine Dry Footworks Healthy Cracked Heel Cream 4129 First Aid Kit Harmony Hemp NeuroComfort Pain Relief Roll-on 1000 Polysporin Plus Pain Relief Toplast Pain Relief Lidocaine 4percent LidoWorx Desert Harvest RELEVEUM Xylocaine - 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Lidocaine FIRST AID Contains 101 PIECES HARDCASE Icy Hot with Lidocaine No-Mess 4190 First Aid Kit IV Infusion CPI Limencin Zcaine Rapid Pain-relief Topical Point relief Lidospot First Aid Only First Aid/ Burn Fruit of the Earth Sun Town City Lidocaine 4 Percent Lidopril XR Lidocaine Hydrochloride Injection, USP 1% Zionodil External Zyvodol The Solution Anorectal Spray Temporary Pain Relief Lidocaine Hydrochloride Topical Solution USP Lidotor Lidocaine and Epinephrine Inj.usp 2% 1:100000 Leader DX2 OraGenomic Medicated DNA Collection Screen JUANCHI Tattoo Numbing Zee Blood Clotting Antiseptic Maximum Strength Pain Relief Lidocaine Patch Terrasil Cold Sore Treatment Max 4302 First Aid Kit DermaRad Relief Basic Care Endure Extra Strength Liquid Insect Bite Relief Gel Hempvana Maximum Strength Pain Relief Topical Anesthetic Dr. Scholl's Cracked Heel Relief Cream Neptune Ice Patch Lidocaine 5% Patch ACTIVE-PAC with Gabapentin After Sun Gel ARC FIRST AID Contains 1000 PIECES Lidocan VI Moshe Numbing Hemorrhoidal Re-Lieved 4% Lidocaine Fabric Tape Harmony Hemp NeuroComfort 4% Lidocaine Pain Relief 500mg Lidocaine Pain Relieving Creme Tatoo Care 4353 First Aid Kit ECOLAB Blood Clotting Alocane On The Go Advanced DNA Medicated Collection Kit III Arrow Two-lumen Central Venous Cathetar Kit Burn Relief Pain Reliever Well at Walgreens Lidotral 3.88 Percent Plus Hydrocortisone 1 Percent Cream Xesso Rear Comfort Glide Numbed As FXXK LevigoSP Atelocollagen Implant Itch Relief Pain Relief Patches K10-lido 4106 First Aid Kit Xylocaine 0.5% W Epinephrine 1:200000 Xolido Cold Sore TREATMENT 3 Step First Aid Kit Lidozol 4362 First Aid Kit Dr Butlers Hemorrhoid and Fissure PF Antibiotic Cream Plus Pain Relief for Kids Lidocan III Treatonic Tattoo Numbing Cream Eha Burn with Lidocaine 4218 First Aid Kit Lido AID 4309 First Aid Kit Pain Relieving Well at walgreens THERA CARE 24hrs Lidocaine Patch 4022 First Aid Kit Equate Pain Relieving Cream Lidocaine Numbs Up 4139 First Aid Kit 4195 First Aid Kit 4281 First Aid Kit ACME FIRST AID Contains 404 PIECES DCH Burn Relief 4234 First Aid Kit Dyve Comfort L Will Relieve Terrasil Itch, Rash and Pain Relief MAX TheraCare 4% Lidocaine Cream QC Cool and Heat Roll-On Lidocaine 23% / Tetracaine 7% 4132 First Aid Kit 4300 First Aid Kit Equate Hemorrhoid Relief Lidocaine Hydrochloride and Epinephrine Injection USP Acunistat-60 Phenyl-Lido CVS Health Lidocaine Pain Relief Mango Bay 0.5% Lidocaine Gel Releevia LM Patch Spinal Anesthesia Tray 1% Ocean Potion Instant Burn Relief Ice Medi-patch With Lidocaine Rx 4319 First Aid Kit SWISS NAVY Endurance Rx 4141 First Aid Kit 4228 First Aid Kit Albertson Lidocaine, Menthol Pain Relief Medicated Patch Marlido Kit Absorbine Jr Pro Cream Diabetic First Aid Gel Curist Lidocaine Can PainBloc24 Flexi-Stretch Pain Tape DermacinRx Lidotral Xylonor Spray Lmx5 Xylocaine Ointment 5% Dragon Pain Numbing Topical Analgesic 4285 First Aid Kit Alocane Plus 4102 First Aid Kit Pain Relief Max Strength GFA First Aid 24 Unit Metal Case Terrasil Itch, Rash and Pain Relief 4274 First Aid Kit Menthocin Patch with Lidocaine Zims Lido Freeze Aubio Life Sciences Lip Lidocaine 3% Topical Anesthetic Cream Painless Tattoo 2 4104 First Aid Kit ReCellTis Wound Cream Lido Pain Relief Lidotral 3.88 Percent Plus Hydrocortisone 1 Percent Lidocaine Anorectal Temporary Pain Relief Spray Jelido Pro-C-Dure 4 Kit Prilovix Terrasil Rash and Pain Relief 4172 First Aid Kit Amazon Basics Pain Relief Patch with 4% Lidocaine Harmony Neuro 4% Lidocaine Pain Relief 500mg Zone 1 Lipritin Lidocaine Dry Patch Plus Menthol lidoForte Hemorrhoidal LidaFlex Velma Pain Relief Patch Avalin-RX Auto 157 Xylocaine 5% Spinal Western Family Aloe Vera Moisturizing ProCoMycin 4298 First Aid Kit Anecream 5 Extra Strength AfterTAT Marlido 25 Kit Odorless Analgesic Roll-on Meijer Zeruvia 4136 First Aid Kit Liprotek Solarcaine Burn Pain Relief BlueStop Max Aspercreme with Lidocaine Essential Oils Rosemary Mint Stag 9000 DelaySpray for men more Indication Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks [F4349, L5930]. Categories Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use Agents that reduce seizure threshold Amides Amines Analgesics and Anesthetics
Anesthetics Anesthetics for Topical Use Anesthetics, Local Anilides Aniline Compounds Antiarrhythmic agents Antiarrhythmics, Class I Antiarrhythmics, Class Ib Antipruritics and Local Anesthetics Antipruritics, Incl. Antihistamines, Anesthetics, Etc. Cardiac Therapy Cardiovascular Agents Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (moderate) Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2A6 Substrates Cytochrome P-450 CYP2B6 Substrates Cytochrome P-450 CYP2C18 Substrates Cytochrome P-450 CYP2C8 Substrates Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Substrates Cytochrome P-450 CYP3A7 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dermatologicals Local Anesthesia Local Anesthetics (Amide) Membrane Transport Modulators Methemoglobinemia Associated Agents Nervous System Neuraxial Anesthetics Ophthalmologicals Otologicals P-glycoprotein inhibitors Peripheral Nervous System Agents Sensory System Agents Sodium Channel Blockers Throat Preparations Vasoprotectives Voltage-Gated Sodium Channel Blockers more ATC-Code S01HA07 D04AB01 R02AD02 C01BB01 S02DA01
N01BB52 C05AD01 N01BB02 more CAS number 137-58-6 
