Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
LYS
Lysine acetate
L-lys
L-2,6-Diaminocaproic acid
(S)-lysine
Lysinum
Lysine acid
6-ammonio-L-norleucine
Lysine dihydrate
Lysine monohydrate
(S)-α,ε-diaminocaproic acid
Lysina
L-Lysine
L-Lysin
Lysine
(S)-2,6-diaminohexanoic acid
Lysine hydrochloride
Brand Names
Aminosyn II
Olimel 5.7% E
Travasol Inj Without Electrolytes 8.5%
Aminosyn-PF
Clinimix E
Aminosyn
Aminosyn II 8.5% Injection
Primene 10%
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
Aminosyn II 10% With Electrolytes
Primene
Aminosyn II 7% With 50% Dextrose
Renamin (amino Acids) Injection
Vamin 18 Electrolyte-free
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
Smofkabiven Extra Nitrogen
Aminosyn-PF 10%
Smofkabiven
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Aminosyn II and Dextrose
Aminosyn 3.5% M
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Aminosyn II in Dextrose
Perikabiven
Smofkabiven Electrolyte Free
Vamin N
Lysakare
Aminosyn II 7% Injection
FreAmine III
Aminosyn II In Dextrose Injection
Plenamine
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Hepatasol
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Aminosyn Sulfite Free
Primene 10%-liq IV
Travasol
Xyzmune
Olimel 4.4%
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn RF Injection
Kabiven
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
20% Prosol
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
HepatAmine
Smofkabiven Peripheral
8.5% Freamine III
Olimel 3.3% E
Travasol E
Clinisol
Travasol Amino Acid Inj 5.5%
Aminosyn II 8.5% With 50% Dextrose
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Nephramine Liq IV
Nutrineal Pd4
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Aminosyn II 7% With 10% Dextrose
NephrAmine
Olimel 7.6%
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Periolimel 2.5% E
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn HF
Olimel 5.7%
Smofkabiven Extra Nitrogen Electrolyte Free
Clinimix
Aminosyn 8.5% Injection With Electrolytes
ProSol
Aminosyn 5%
Imubolic
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Travasol Inj Without Electrolytes 5.5%
FreAmine HBC
Essepna
Novamine
RenAmin
Aminosyn II with Electrolytes in Dextrose with Calcium
Aminosyn 10% W Electrolytes
TrophAmine
Olimel 7.6% E
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Aminosyn II with Electrolytes
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Effervescent Potassium Chloride
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Synthamin
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn 7%
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Aminosyn RF
ProcalAmine
Olimel 4.4% E
Aminosyn-PF 7%
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn II 5% Inj
Travasol Amino Acid Inj 8.5%
Aminosyn 8.5%
Premasol - sulfite-free (Amino Acid)
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
