OXY

OXYGEN MOLECULE

Created:1999-07-08
Last modified:  2024-09-27

Help

Find related ligands:

Chemical Details

Formal Charge0
Atom Count2
Chiral Atom Count0
Bond Count1
Aromatic Bond Count0
2D diagram of OXY
Toggle HydrogenToggle Labels

Chemical Component Summary

NameOXYGEN MOLECULE
Systematic Name (OpenEye OEToolkits)molecular oxygen
FormulaO2
Molecular Weight31.999
TypeNON-POLYMER

Chemical Descriptors

TypeProgramVersionDescriptor
SMILESCACTVS3.341O=O
SMILESOpenEye OEToolkits1.5.0O=O
Canonical SMILESCACTVS3.341 O=O
Canonical SMILESOpenEye OEToolkits1.5.0 O=O
InChIInChI1.03 InChI=1S/O2/c1-2
InChIKeyInChI1.03 MYMOFIZGZYHOMD-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License
DrugBank IDDB09140 
NameOxygen
Groups
  • approved
  • vet_approved
DescriptionOxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.
Synonyms
  • Pure oxygen
  • Dioxygen
  • Oxigeno gaseoso
  • Oxygen USP
  • Molecular oxygen
Brand Names
  • COMPRESSED Gas, N.O.S.
  • Lung Diffusion Test Mixture Gas
  • Oxygen/Nitrogen 52/48
  • Helium Oxygen Mix 80/20
  • Medical Air U.S.P.
IndicationOxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia [L745] to reduce the extent of hypoxia-induced tissue damage and malfunction.
Categories
  • Chalcogens
  • Elements
  • Gases
  • Medical Gases
  • Miscellaneous Therapeutic Agents
ATC-CodeV03AN01
CAS number7782-44-7

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License
NameTarget SequencePharmacological ActionActions
Cytochrome c oxidase subunit 1MFADRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGNLLGN...unknownagonist,activator
NADPH oxidase 1MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTL...unknownagonist,activator
Hemoglobin subunit betaMVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLS...unknownbinder
Hemoglobin subunit alphaMVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLS...unknownbinder
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 977
ChEMBL CHEMBL1234886
ChEBI CHEBI:26689, CHEBI:15379, CHEBI:27140
CCDC/CSD LOZNET, DEFHII, YUZLEN, ZIVSOP, YUJKIA, TUWWEO, ITEVUY07, ITEVUY01, ASAKUA, ITEVUY08, ITEVUY03, ITEVUY04, BEVFEP, ITEVUY05, BEVFUF, ITEVUY02
COD 9017506, 9017498, 9017889, 2106431, 2106877, 1512527, 1528336