SAL

2-HYDROXYBENZOIC ACID

Created:1999-07-08
Last modified:  2024-09-27

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Chemical Details

Formal Charge0
Atom Count16
Chiral Atom Count0
Bond Count16
Aromatic Bond Count6
2D diagram of SAL

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Chemical Component Summary

Name2-HYDROXYBENZOIC ACID
SynonymsSALICYLIC ACID
Systematic Name (OpenEye OEToolkits)2-hydroxybenzoic acid
FormulaC7 H6 O3
Molecular Weight138.121
TypeNON-POLYMER

Chemical Descriptors

TypeProgramVersionDescriptor
SMILESACDLabs10.04O=C(O)c1ccccc1O
SMILESCACTVS3.341OC(=O)c1ccccc1O
SMILESOpenEye OEToolkits1.5.0c1ccc(c(c1)C(=O)O)O
Canonical SMILESCACTVS3.341 OC(=O)c1ccccc1O
Canonical SMILESOpenEye OEToolkits1.5.0 c1ccc(c(c1)C(=O)O)O
InChIInChI1.03 InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKeyInChI1.03 YGSDEFSMJLZEOE-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License
DrugBank IDDB00936 
NameSalicylic acid
Groups
  • investigational
  • approved
  • vet_approved
DescriptionA compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Synonyms
  • O-hydroxybenzoic acid
  • Potassium salicylate
  • Choline magnesium trisalicylate
  • 2-Carboxyphenol
  • Sodium salicylate
Brand Names
  • Proactiv Clear Zone
  • DR.Luke Liquid Wart Remover Mask
  • Almay Clear Complexion Blemish Healing Spot Concealer
  • Neutrogena Oil Free Acne Stress Control Triple Action Toner
  • OXY Daily Defense Ultra Facial Cleanser
IndicationKey additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
Categories
  • Acids, Carbocyclic
  • Agents causing hyperkalemia
  • Agents that produce hypertension
  • Analgesics
  • Analgesics, Non-Narcotic
ATC-Code
  • D01AE12
  • G04BX17
  • N02BA04
  • N02BA12
  • S01BC08
CAS number69-72-7

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License
NameTarget SequencePharmacological ActionActions
Carbonic anhydrase 6MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPI...unknowninhibitor
Carbonic anhydrase 12MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSC...unknowninhibitor
Carbonic anhydrase 2MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS...unknowninhibitor
Carbonic anhydrase 4MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDR...unknowninhibitor
Carbonic anhydrase 1MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISV...unknowninhibitor
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL424
PubChem 118212070, 338
ChEMBL CHEMBL424
ChEBI CHEBI:16914
CCDC/CSD HAGTOY, BUVBIG, BUVBIG02, HUWHAK, KUJDIE, GEYSAE02, EJIFIO, IFEFUX, GOKQUV01, BUVBIG01, DKPSAL10, DOGCAG, LATLAV, CIXMED, GOKQUV, ENICEK, BULKOK, EZEGIA, KOPKEH, LATKUO, HOYXIE, IFEFOR, CEKNEN, KIGLES, GEYSAE, DUPXEU, HOGFEQ, ACETAF, GIHCAD, CARTEW, HUNJIL, KIGLES01, BULJID, DUPXIY, KIJKUL, APYSAL, IZAHEZ, KOPKEH01, CUWFIM, AVEHER, GAHZOI, KOPKEH02, AQEJEO
COD 2100548, 2022076, 4504244, 1519837, 4503560, 7214357, 7208274, 4500305