SAL

2-HYDROXYBENZOIC ACID

Created: 1999-07-08
Last modified:  2024-09-27

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Chemical Details

Formal Charge0
Atom Count16
Chiral Atom Count0
Bond Count16
Aromatic Bond Count6
2D diagram of SAL

Chemical Component Summary

Name2-HYDROXYBENZOIC ACID
SynonymsSALICYLIC ACID
Systematic Name (OpenEye OEToolkits)2-hydroxybenzoic acid
FormulaC7 H6 O3
Molecular Weight138.121
TypeNON-POLYMER

Chemical Descriptors

TypeProgram Version Descriptor
SMILESACDLabs10.04O=C(O)c1ccccc1O
SMILESCACTVS3.341OC(=O)c1ccccc1O
SMILESOpenEye OEToolkits1.5.0c1ccc(c(c1)C(=O)O)O
Canonical SMILESCACTVS3.341 OC(=O)c1ccccc1O
Canonical SMILESOpenEye OEToolkits1.5.0 c1ccc(c(c1)C(=O)O)O
InChIInChI1.03 InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKeyInChI1.03 YGSDEFSMJLZEOE-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank IDDB00936 
NameSalicylic acid
Groups
  • approved
  • vet_approved
  • investigational
DescriptionA compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Synonyms
  • Sodium salicylate
  • Choline magnesium trisalicylate
  • ácido salicílico
  • O-hydroxybenzoic acid
  • Diethylamine salicylate
Brand Names
  • bareMinerals Blemish Rescue Skin-Clearing Loose Foundation Medium 3C
  • Kerastase Paris K Symbiose Serum Nuit Antipelliculaire Intensif Antidandruff Treatment
  • Specific Beauty Clarifying Wash Acne Treatment Cleanser
  • Aliclen
  • CLEAR AND COVER ACNE TREATMENT CONCEALER CLEAR AND COVER ACNE TREATMENT CONCEALER 11 coffee
IndicationKey additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
Categories
  • Acids, Carbocyclic
  • Agents causing hyperkalemia
  • Agents that produce hypertension
  • Analgesics
  • Analgesics, Non-Narcotic
ATC-Code
  • D01AE12
  • N02BA04
  • N02BA12
  • S01BC08
CAS number69-72-7

Drug Targets

NameTarget SequencePharmacological ActionActions
Prostaglandin G/H synthase 1MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFG...unknowninhibitor
Prostaglandin G/H synthase 2MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFY...unknowninhibitor
Aldo-keto reductase family 1 member C1MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHID...unknowninhibitor
Cytochrome P450 2C9MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDI...unknownsubstrate
Serum albuminMKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...unknownother/unknown
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL424
PubChem 338, 118212070
ChEMBL CHEMBL424
ChEBI CHEBI:16914
CCDC/CSD HAGTOY, BUVBIG, BUVBIG02, HUWHAK, KUJDIE, GEYSAE02, EJIFIO, IFEFUX, GOKQUV01, BUVBIG01, DKPSAL10, DOGCAG, LATLAV, CIXMED, GOKQUV, ENICEK, BULKOK, EZEGIA, KOPKEH, LATKUO, HOYXIE, IFEFOR, CEKNEN, KIGLES, GEYSAE, DUPXEU, HOGFEQ, ACETAF, GIHCAD, CARTEW, HUNJIL, KIGLES01, BULJID, DUPXIY, KIJKUL, APYSAL, IZAHEZ, KOPKEH01, CUWFIM, AVEHER, GAHZOI, KOPKEH02, AQEJEO
COD 2100548, 2022076, 4504244, 1519837, 4503560, 7214357, 7208274, 4500305