SEP

PHOSPHOSERINE

Created:	1999-07-08
Last modified:	2024-09-27

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24 entries where SEP is found as a standalone ligand7 entries where SEP is covalently linked to polymer or other heterogen groups 1,971 entries where SEP is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	19
Chiral Atom Count	1
Bond Count	18
Aromatic Bond Count	0

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Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	PHOSPHOSERINE
Synonyms	PHOSPHONOSERINE
Systematic Name (OpenEye OEToolkits)	(2S)-2-amino-3-phosphonooxy-propanoic acid
Formula	C₃ H₈ N O₆ P
Molecular Weight	185.072
Type	L-PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=P(O)(O)OCC(C(=O)O)N
SMILES	CACTVS	3.341	N[CH](CO[P](O)(O)=O)C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C(C(C(=O)O)N)OP(=O)(O)O
Canonical SMILES	CACTVS	3.341	N[C@@H](CO[P](O)(O)=O)C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C([C@@H](C(=O)O)N)OP(=O)(O)O
InChI	InChI	1.03	InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
InChIKey	InChI	1.03	BZQFBWGGLXLEPQ-REOHCLBHSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB04522
Name	Dexfosfoserine
Groups	experimental
Description	The phosphoric acid ester of serine.
Synonyms	Serine phosphate Dexfosfoserine Phosphoserine
Categories	Amino Acids Amino Acids, Neutral Amino Acids, Peptides, and Proteins Phosphoamino Acids
CAS number	407-41-0

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
3-phosphoinositide-dependent protein kinase 1	MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPA...	unknown	inhibitor
Glycogen phosphorylase, muscle form	MSRPLSDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPR...	unknown	inhibitor
Protein kinase C theta type	MSPFLRIGLSNFDCGSCQSCQGEAVNPYCAVLVKEYVESENGQMYIQKKP...	unknown	inhibitor
Serine/threonine-protein kinase pim-1	MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFG...	unknown
Glycogen phosphorylase, liver form	MAKPLTDQEKRRQISIRGIVGVENVAELKKSFNRHLHFTLVKDRNVATTR...	unknown
Phosphomannomutase/phosphoglucomutase	MSTAKAPTLPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPC...	unknown
cAMP-dependent protein kinase catalytic subunit alpha	MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTL...	unknown
Anti-sigma F factor antagonist	MHFQLEMVTRETVVIRLFGELDHHAVEQIRAKISAAIFQGTVTTIIWNLE...	unknown
Fimbrial protein	MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQ...	unknown
Alkaline phosphatase	MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGARRLTGD...	unknown
Rhodopsin	MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVL...	unknown
Serpin B3	MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTA...	unknown
Endo-1,4-beta-xylanase Y	MKNKRVLAKITALVVLLGVFFVLPSNISQLYADYEVVHDTFEVNFDGWCN...	unknown
Serine/threonine-protein kinase TAO2	MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRN...	unknown
Voltage-gated potassium channel KCNC4	MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETY...	unknown
Lithostathine-1-alpha	MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYF...	unknown
Mothers against decapentaplegic homolog 2	MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVK...	unknown
Glutaminase 1	MKELIKEHQKDINPALQLHDWVEYYRPFAANGQSANYIPALGKVNDSQLG...	unknown
Siroheme synthase	MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALTFIPQFT...	unknown
Phosphocarrier protein HPr	MEKKEFHIVAETGIHARPATLLVQTASKFNSDINLEYKGKSVNLKSIMGV...	unknown
Cystic fibrosis transmembrane conductance regulator	MQRSPLEKASVVSKLFFSWTRPILRKGYRQRLELSDIYQIPSVDSADNLS...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682