VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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22 entries where VIB is found as a standalone ligand

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152
Name	Thiamine
Groups	investigational approved vet_approved nutraceutical
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Thiaminum thiamine(1+) Tiamina thiaminium Thiamin Antiberiberi factor Vitamin B1 Aneurin thiamine(1+) ion Thiamine Thiamine hydrochloride Thiamine mononitrate Thiamine chloride
Brand Names	Multi-phyto Capsules Liqui Infant Vitamins Dialyvite with Zinc Mega Plex IV - Pck Mvc 9+4 Inj Penta-thion Pwr Poly-Vite Pediatric Oral Solution Prenatal Plus Vitamins Thiamiject Injection - Liq Im IV 100mg/ml Vitalife - Capsule Phosthenine Vitamines Et Fer (ampoules Buvable) Tricare Prenatal DHA One Vita-vim With Beta-carotene - Tab Vitamin B Complex Suppl M.V.I. 12 M.V.I. Pediatric Lexazin Multivitamins and Multiminerals Formula Regular Tablet Garfield Chewable Multivits Plus Iron Tab Vena-Bal DHA Palm Springs Multvit and Min Tab Vitrexyl Children's Vitamins Chewable L.C. Supplement CompleteNate Chewable Dynam Ampoule Et Tablet Renate Thiamine Hydrochloride Injection USP, 100mg/ml Totalvit Plus Vitamin B Compound W C Tab 500mg RE Nata OB Swiss One Timed Release Tab PNV Tabs 29-1 Cda-21 Vitamins With Non-medicinal Probiotic Complex Multivitamine Surbex-500 With Zinc High Potency Multivitamins & Minerals Caplets Twin Opti Pwr Vita Vim Multivitamins and Minerals Tab Lipotropic Ctr THIAMINE HCl Taron-C DHA Poly-VI-flor Central-vite 18 Essential Super-pote Vitamin Supplement PNV Prenatal Vitamin Liqui B Complex Plus Mvc One Per Day Vitamin and Mineral Dietary Supplement Kanga-V Multivitamins & Minerals Dialyvite 3000 Livita Children Novel Vita Children's Chewable Multivitamins With Minerals Stress B Capsules With Vitamin C Materna-tab Supravite Bouteille 250ml Hi Potency B52 B Complex Tab Children's Chewable Multivitamins and Minerals Pregnancy Multivitamin Folic 5 Prenatvite Prometa Venexa vitaMedMD Rx Plus Ferra Naka Plus Vitamins Vitrexate Gynedyn Tab Zoo Chews Plus Iron Se-Natal One Maxi 10 Tab G.A.S. Complex CitraNatal 90 DHA Floravit - Syr Vitamin B Complex Plus 300mg Vitamin C Efferlife Multivitamins and Minerals Jenliva Omega-3 Rx Complete Thiamine HCL 100 mg Viamon Ampoules Et Comprimes Vita-B-75 Cap Virt-Tabs OB Complete 400 VitaXyme Vitramyn Vitamin B Complex 100 Tab Multi-vitamins With Minerals Timed Release B-complex 50 Premium Prenatal Luna Vitamin and Mineral Bar for Women Adult Infuvite Multiple Vitamins Preplus Folica-V Vc II Infuvite Adult SetonET-EC Chewable Multiple Vitamins Plus Extra C Zatean-Pn Multi Vitamin-mineral Formula PreNatal Vitamins Plus TL-Fluorivite Swiss Total One Nutra Boost Livita Adults Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass One-A-day Advance Men's Complete Multivitamins and Minerals Tablets Timed Release Foltabs Prenatal Multi Vitamin and Mineral vitamin Kanga-kid Multi-vitamin & Mineral Somavit Brand Vitamins and Minerals Complex Beminal W C Fortis Inj Formula B Super Charged Energy Fusion Plus Mebolic Trinatal Ultra Formula Hh Kindervites Multi Pro Dia-vite Prenatal Mega Antioxidant Men's Biomultiple Vitamin and Mineral Supplement Stress B-complex Plus Iron With Vitamins C&e Select-OB Plus DHA Prenatal Supplement Plus DHA Multi-11 B Complex 25mg Vitamin Supplement Isotonix Multitech Vitamin Mineral Supplemen Multivitamines Plus Fer Pour Enfants (chewable Tablets) NephPlex Rx Revitex Ampoules Et Comprimes Vigem 12 Liquid Hormodausse Plus Calc Et D Tab Viva CT Prenatal B-plex Mega Balance ahoSAN Dexatran Virt-Nate DHA Lipovite Balanced B50 Complex Kanga-B Vitamin B Group + C One-A-day Advance Fem - Tablets 50 Plus Materna Multi Vitamin & Minerals Multiple Vitamins Tab PreferaOB plus DHA Tini-cal Ampoules Phytofortis + Calcium A-D Prenate Star Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Childrens Multiple Vit and Min Chew Tab B-50 Complex Stress B With 1000 Mg Vitamin C Antlerviron Children's Chewable Multi-vitamin Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops bioJET Infuvite Pediatric Pregvit Active OB Cedevita Sugar-free Vitamin Supplement For-2 Focalgin 90 DHA B-1 Caps 500mg Children's Chewable Multi Vitamins Cavan Folate DHA NEONATAL Complete Maltlevol Liq Envirocomplex Poly-Vi-Flor Pregvit Folic 5 Prena1 Plus Essential B Tablets TriAdvance Twin Ultra Liquid Fruit Punch Flavor Children's Multivitamins With Iron Complex 5 - Pwr Maxine Vitamin and Mineral Supplement Chewable Multiple Vitamins Plus Iron Tab Relnate DHA Wellness Formula B-plus - Tab RayaVit Kaydia Patch Virt-PN Multiple Vitamins With Iron Tablets Prenatal Formula Tab Multi Vitamin Drops with Fluoride Synergistic Manganese Capsules Vitamin B Complex Prenatrix Vp-heme Ob Bewon Elixir 0.05mg/ml High Potency Vitamin B Complex + C Tab Kids Stuff Tablets Multi Vitamin Drops with Fluoride with Iron Omnivex One A Day Multiple Vit W Minerals Paire OB Plus DHA Se-Natal Multinate DHA Extra Vitamin B Complex W C Tab NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Natal-V RX Multi-vitamin/Multi-mineral B Complex Tablets Ultra Hr Vita-worth B-complex Tablets Supravite Stress Avec Vit E Et Fer INATAL Ultra Multiple Vitamins and Minerals Stresstabs + Zinc-copper Vitranol Fe Thrivite Rx VIL-Rx Virt Nate Chewable Multivitamins Neonatal Plus Vitamin Vita-Pac Thiamine HCl Inj 100mg/ml Maxum Multi-vite Multi Vitamin, Iron and Fluoride Onccor Vita Plex Tab Vitaflex Dietary Suplement Prenatvite Plus Phytopure Spark Cap Cedevita Plus Vitamin Supplement Vitamin B-Complex Super Vita Vim Multivitamins and Minerals Super Vitalex Ampoule Buvable Stress B Complex With C, E and Iron Tab Childrens Chewable Vitamins Prenatal, DHA P.N. Vitamin-mineral Drink WesCaps Marnatal F Magnum-75 Vitamin and Mineral Supplement Duet DHA Children's Chewable Multivitamin Complete With Minerals Stress B Complex With C and E Tab Kid's Choice Children's Chewable Vitamins - Tab Vitranol Spectrum Performa Multivitamins and Minerals Tablets Surbex 500 Filmtab Folivane-OB B Complex 50+ Caplet Fortaplex Inj Liquid B Complex 50 Se-Plete DHA Paramettes Chewable Multivits With Iron Tab Folic-K Multivitamines Et Mineraux Sopalamine/3b Tab PreGen DHA HemeNatal OB Nephrocaps-QT Oncovite Cavan Alpha Nutrifer Plus Tablets Multi 1000 Thiamine HCl Tab 100mg Vitaplex MVC-Fluoride Children's Chewable Multi-vitamin Complete With Minerals Iron, Vit & Min Supp One A Day Tab Quflora Pediatric Junior Multi Vitamins - Regular RenaPlex Megavites Tab PreTAB Pretrate Hemarexin Liquid and Drinkable Ampoules Women's Change Formula Multivitamins for Children Chromease Tab B-50 Hi Potency B Vitamins Tab HemeNatal OB plus DHA Nephrocaps Nutra-Z B-Combo Flintstones W Extra C Tab Stress Tab With Iron and Vitamin E Genicin Vita-S Vitazyme Vitamine B1 Tab 100mg USP Vitamines Et Mineraux Balanced B-50 B-complex Vitamins, Timed Rele Allbee C 800 Tab MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement Tricare Prenatal 2-part Daily Prenatal Vitamin System B Totum 500 Se-Tan PLUS Vasula Tab B Complex W Vit C W Non-med Yeast&liver Tab Childrens Chewable Vitamins W Iron Milltrium Senior Vitamin and Mineral Supplement Active FE Vitogen B Stress C Vit E Zinc & Cop Duet DHA 400 Multivitamins and Minerals - Complete Neomultivite Somarexin and C 1000 Super Pantoplex Multi-Vitamin With Fluoride Revit Plus Cap T.R.I. B-plex Src Foliflex Supravite Stress Avec Vit E Cuivre Et Zinc Men's 50+ Venexa FE Complete Mega B PreQue 10 Multipack II Gestamine Comprimes Natalvirt 90dha OB Complete DHA Multi Tabs Vinacal Multivitamins W Iron Geritol Liquid Dothelle DHA Women's Biomultiple Vitamin and Mineral Supplement B Virol DuetDHA Complete Escavite D Swiss One Bewon Elixir Abavite OB Complete Prenatal B1 Tab 100mg Multi-force for Adults Tab D'pantothenic Acid-B1-B2 Tab Fizz Multivitamins for Kids W C Loz Multiple Vitamins Childrens Chewable Fem Time Tab Multiple Vitamins Plus Iron for Women Neo-bex Strovite One Caplets Vitrexyl plus Iron Multi-Vit with Fluoride B Vitamin Compound With B12 Thunas Ventrixyl V-Natal Neonatal Vitamin Replavite Synergistic Manganese Cap Multinate DHA B-100 Hi Potency B Vitamins Tab Multi Plex II - Tab PR Natal 400 Bal-Care DHA Children's Chewable Vit and Min Tab Multi Flow Tablets Balanced B-50 B-complex Vitamins Tab Childrens Chewable Vitamin Tab Stress Complex 600 Avec Vit E Cuivre Zinc TM-Vite RX Vita Day Tab Vitamin B-1 100 Mg Tablets Xyzbac Olympian Multi Vit Plus Minerals Tab Master Key Multi Vitamin Multi Mineral Formula 2 Multi Vitamins & Minerals Multi B B Complex With C 550mg Q.T. #4 Vitamin and Mineral Dietary Supplement Tonimol Cap Liq Multi-Vitamin Fluoride Drops Tonicol Et A-D-C Ampoules/comprimes Complexe B-75 Floradix Formula Liq Multisol Revit Tab Innersource Tab tensioSAN Kimchi Vitamin chewable multivitamin NataChew Vitamines Pour Bebes Et Enfants Prenatabs FA Ultimate Tab Poly-Vi-Flor with Iron Vital-D Rx Choice OB DHA Alkadrenergy Tablets Multivit with Fluoride Genicin Vita-Q Davimet-M Vitamin and Mineral Supplement - Liq Corvite Free Vitaphil 90 DHA Potassium Plus Vit B Complex For Kids Only Chewable Multivitamins - Tab Vit B Complex Plus Vit C 550mg M.V.I. Adult Neo-bex Injectable Body Rox Nutri-Tab OB CitraNatal DHA Animal Shapes w/Iron Chewtabs B-complex-50 Tab Complexe B 75mg Duet DHA Balanced B-100 Complex Tablets healthy mamaBE WELL ROUNDED BE WELL ROUNDED Neo Vites Tab Prenatal Plus Multivitamin Plus DHA MiniCaps Floriva TL-Folate Tandem OB Omniquin Concept DHA Chew.multiple Vits.with Extra C for Children Vita-vim - Tab Zeldana Cc II Maximum Once A Day B Complex 500 Tab Beminal Fortis Elx Multiple Vitamins and Minerals Capsules Children's Chew Multi & Min Tab Low Potency B Complex Tab Appedrine Ultimate OB DHA Women's Formula Betaxin Liq 100mg/ml For Kids Only Chewable Multivitamins Multi-force for Women Tab Toni Com Liq Daily-Vite Fortamines 10 Capsules B-100 Caps Twin G.F. Powder Vanilla Flavor Vitamine Du Groupe B Plus Fer - Liq Prenatal Super B Compound W 500mg Vit C Fibrik Vitafol OB Caplet Chewable Adult Multivitamins With Minerals Multivitamines Pour Enfants (chewable Tablets) Orange Flavored Crystal Chews Tab Re Ob 90 DHA Poly-Vitamin with Fluoride Multiple Vitamin Tab Great Day/am Formula Tab Tender Age Multi Vitamins E.S.T. Complex Twin G.F. Powder Se-Care Conceive B Complex With C 300mg Tab C-B Complex Enviroflex - Tab Complexe B Compose 75 Vitamin B Compound Tab Croq-vit Pour Enfants Stress Tab With Zinc, Copper and Vitamin E Stress B Complex With C,e, Zinc and Copper Vimeral Tab Viva Kids - Tab NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Niva-Plus Nutrol-B-complex Only One - Tablet Permathene-12 - Caplet Vasculine Formula Pro-B Vtb Vitamin and Mineral Supplement Vasodyn Tab Formula Gly Multivitamin NESTABS Prenatal Multi-vitamin/Mineral Supplement OB Complete Petite Fortistress Tab Davimet with Fluoride FolaMed DHA Iberet 500 Integra Plus Mega Plex III - Pck Multiple Vitamins Plus Iron - Tab Children's Chewable Tab Advanced B & T Formula Formula O.C. Orti B Prenatal Vitamins Plus Low Iron Revit Multi-vitamins and Minerals Hylazinc Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops PureFe Plus Enrich Core Pack - Children Vitamin and Mineral Supplement Forty Plus Vitamin Supplement Childrens Chewable Multivitamins W Iron Natal PNV Meplex T 750 Multivitamin with fluoride Bal-Care DHA Essential Poly-Vi-Sol Multitabs Formula Gm Tricare Prenatal Quick Dissolve Thiamine HCl Tab 25mg Lorid Dialyvite Supreme D Vita-amine Cap 100mg Glyco Lite Ect B Plus C 300 mg Beminal With C Fortis Cap Swical-energy 3e Age B 6 Plus Nutrilite Double X Swiss One Multivitamin and Mineral Caplet Vege Swiss One Multivitamin W Chel Mins Tab Trinaz Folica BE Multivitamins and Minerals for Young Men Focalgin CA Twin Ultra Liquid Orange Flavor Vol-Plus Premium Prenatal - Tablets Kanga-kid Vitamins & Iron Twin Ultra Liquid Lemon-lime Flavor One Daily VITES Provida DHA B50 Complex Nutri-Tab OB plus DHA Children's Chewable Multi Vit W Iron Multivitamin Drops with Fluoride Multivit Et Fer Ampoules Et Comprimes Vinate AZ Vitamin B + C Cap Vyo Cylate - Pwr Multivitamins and Minerals for Women vitaMedMD One Rx 50 Plus Multiple Vitamins & Minerals Centratex Multiple Vitamins Plus Iron Tab Multiple Vitamins Multi Vitamin Drops with Fluoride and Iron Chela-manganese 50 Plus Gesticare DHA Multi-Vit-Flor Amladex Multivitamins and Minerals for Young Women P.R.O. Complex Vyqua WesNatal DHA Complete Davimet with Iron Complete One-A-day - Tab Multi-Vit with Fluoride and Iron Multi Vitamin - Mineral Complete-RF Prenatal Se-Natal 19 Vitamin B Complex + C 300mg Cap Multivitamins and Minerals for Men Vit B1 Ctr Srt 100mg Avon Vitadvance Multi-kids Complete Distilpure Msm B Stress C + Iron & Vite Hill.vite Chela Iron Plus C,b Complex Davimet Prenatol-M Children Choice Multivitamin W Iron Chew Tab Multi-Vitamin with Fluoride Multi-vitamines Enfants Comprime Neonatal19 Hyporyl - Tab Provida OB Hemocyte Plus Right Choice A.M. Multi Formula - Caplet Balanced B-complex Vit + Vit C&e Tab Feminique W Iron and Calcium Tab Multivitamines Reno Caps Vitamin B1 Tab 100mg USP B 50 Capsules Gtf-vitamin-minerals & Pancreatin Tab Adult Formula 50+ Multitol-M Multi-12/k1 Pediatric Multi #2 FolaGent DHA RenaPlex-D B50 B Complex Tab Thiamine HCl Injection - Liq 100mg/ml Ziphex Phytovim Cap Neonatal DHA Multi-Vitamin Fluoride and Iron Drops Surbex-500 With Iron Escavite Children's Chewable Multiple Vitamins - Tab Prenatal Plus Vitafol Fe Plus B6 Plus Tab Vitamin B Compound W Vit C 250mg Tab Maltlevol 12 Liq Lipo-B-C Tab Multivitamines Et Mineraux Junior Regulier Nitro Vites - Tab TRONVite Osteo-force Dayavite Irospan 24/6 Prena1 Rocky Mountain Multiple Vit and Min Mega Tab Total Living Concepts Formula One - Tab Multiple Vit Plus Iron Tab Renal Caps Dialysis/Stress Vitamin Supplement Multiple Vitamins With Minerals Tablets Doctor's Choice Brand for Men Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Hi Potency B Complex W Chelated Minerals PreNatal 19 Paramettes Adults Balanced B100 PureFe OB Plus PNV Prenatal Vitamin Plus Vitamin A Vitamin B1 Tab 2mg USP Vitafol Ultra AzesChew Edge OB B-complex Tab Mega Capsules NeuroBion O-Cal Prenatal Vitamin MultiVitamin with Fluoride Vitamine B1 100 Mg - Tablet Glyco Plus Ect B Complex Plus C 300mg Tab CitraNatal Essence Multi Plex I - Tab Finazol Z Bec Tab B Complex 50 Vitamin Cap Infant Multivitamin Drops Leritone Junior Mega-vim 75 With Beta-carotene - Tablets Childrens Chewable Multiple Vitamins W.iron Revitalize Multi-vitamin and Mineral Complex Mycelized Childrens Multi-vitamin Liq Prenatal Vitamins Plus Bacmin Maxi 6 Liq Tandem Plus Folika-T Children's Chewable Multiple Vit.plus Iron Childrens Chewable Multivitamins One A Day Advance Adults Poly-Vite/Iron Oral Solution Poly-VI-sol Drops Vita B + C 500 Tab Protect Plus SO 60 Multiple Vitamins W Iron Tab Stress Formula Tab Vitabanks Vitamin Tab Maintain Multiple Vitamin & Minerals Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Swiss One Multi Vit & Chel Min Tab Dexatrim Tablets Vigo Multivitamins Drops/lozenge Children's Chewable Multivitamin and Multimineral N.E.U. Complex Natalvirt Ca Vita Balance 2000 Chela-chromium 200 Stress Formula Multivitamin Tablets USP Complete Natal DHA Hi Potency Multi Tab Pediatric Infuvite Multiple Vitamins Infa Drops Multivitamins Zyvit 24 Multivitamins + Minerals Allbee With C 550 Cap Cyroplex Stress Formula + Iron Tricare Prenatal Select OB Insur-all Vitamin Supplement Quflora FE Pnv-OB-dha Thrivite 19 Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) PNV Prenatal Plus Multivitamin Vege 1 Daily Tab Vitamin B Complex 50 Adeks - Dps Timed Release B-complex 100 Quflora FE Pediatric Drops Virt-Pn Chewable Multiple Vitamins Tab Bev 29 Tab Children's Chewable Multi Vitamins With Iron Tablets Multi - N.T.O.x Formula - Tab Multi Vite Liq Adult Neo-vites & Minerals Tab NovaMV Multivitamin Formula D.S. Multi 12 Injection Soluvit N Thiamine Hydrochloride Inj 100mg/ml USP Complete One A Day Tab Allbee With Vitamin C Cap Vitamin B-1 Thiamine HCl 100mg Dalivit Senior Multi One Foltabs Prenatal Plus DHA Children's Multivitamins TriphroCaps MI-Vite RX Multivitamin with 1.0 mg Fluoride Manganese 50mg Plus B1 & E Tab Multi Vitamin Plus Iron Stress B Complex With C, E & Iron Hi Potency Balanced B-100 Complex - Tab Prenatvite Complete Multi Vitamines - Liq Zoo Chews Super Vita-vim With Beta-carotene - Tab CitraNatal Assure Corvite Chela Potassium Plus Stress Tab Revival 1 Tab Timed Release Vita-vim Srt WesNate DHA C.R.T. X Multivitamin & Mineral Powder Mix Materna - Tab Flintstones Multiple Vitamins Tab Prenatal Vitamin and Mineral Supplement Tab Vitafol-OB Plus DHA Prenatal Supplement Plus DHA THIAMINE HYDROCHLORIDE injection, solution Vitamine 110 Liq B-complex 100 VP-Vite Rx Formula Fm Vitamins & Minerals Tab Complex-75 Ultra Enerforce Vitamin B Cpd W Vit C Tab Multi Vitamin with Fluoride Multitam Pro Hers Vanilla Vitafant Infantol Drops B-complex 50 PreferaOB Vitamines Et Mineraux Comprimes Phytoplex B Liq MultiVitamin Drops with Fluoride and Iron Vitasure WesCap-C-DHA Daily Energy Brand B-complex Dialyvite Prenatal Vi-min Prenatal Vitamin and Mineral Supplement -tab Nata Komplete Prevital Tab B-50 Complex Tab Virt-Bal DHA Plus Ventrixyl Fe Children's Vitamins W Iron Chewable Deriton Multivitamins and Minerals Tablets Hemarexin Tab Folivane-Plus with Ascorbic Acid Precursors PM Caps Strovite Forte Caplet Prenate Elite Chewable Multiple Vitamins for Children SetonET Super Multi Supravite Pour Enfants Multiple Vitamins and Minerals Tab Fortamines-10 Comprimes L-Methyl PNV DHA Super Stress Capsules Livron Plus Tab Everyday Multiple Vitamins With Iron H.W. Children's Chewable Multi Vit & Mineral Men's Virt-C DHA Multi-actin PR Natal 430 Vitogen B Stress C600 Multivitamin & Multimineral Ellis Tonic hormaSAN forte Childrens Chew Multi Vitamin Tab Stress Formula Multi-B Comp + 500mg Vit C Cap Polymine Avec Zinc Et Cuivre Iron Polysaccharides Folic Acid DHA Floriva Plus PNV-Select Stress B&c Tab Hypo Vites Tab Iron Folate Plus Gtf Support Caplet Mini-B Tab Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Men's Multi Master Formula Time Release B 100 Compound - Tablet Extra P.N. Vitamin-mineral Drink Mix B-complex B-plex 100 Century Complete Kids Stuff With Iron Tablets Vitamin B Complex Plus C 300mg Timed Release Q.T. Vitamin and Mineral Drink Mix Balanced B-50 Complex Kenwood Liquid Supplement Livron Plus Ampoule Corvita Multra With Iron Prim - Royal P.M.T. Multivitamins W Minerals Extra Strength Supravite C 1000 Twin Ultra Liquid Grape Flavor Natural Source Spectrum With Beta Carotene Childrens Chewable Multiple Vitamins Plus Fe Orifer F Nephron FA Vitamin B1 100mg Tablet Quflora Pediatric Drops Folitin-Z New Chapter's D'adamo 4 Your Type Multiple for Type O B-100 Vitamin Supplement Vitamin B Complex 100 Virt-Nate Stress Tablets M-Natal Plus MultiVitamin with Fluoride Drops Multi-12 Pediatric Azesco Liqui B Complex Prefera OB plus DHA Zalvit Poly Vi Flor Chewable Tab Multiple Vitamins With Iron Paramettes Multivits Plus Iron Tab (teens) Mega Vitaminerals B With C 500 Cap Multi Spectrum - Tablet Triveen-Duo DHA NataFort Thiamine HCl 100mg W C 20mg Vitafer - Liq Multi-kid Vita Vim With Beta Carotene-caplet Hemarexin Amp Original Bioscal Forte Multi-vitamin Supplement Capsules Reaphirm Plant Source DHA Ply Vi Sol Chewable Tab Swical-energy-2 Prenatal and Post Partum Supplement B Complex With C 300mg Dexifol Multi Rol Concept OB Numark Multivitamins Flintstones Multiple Vitamins Renate DHA Tendera-OB Sibergin B - Cap PrePLUS Tricare Prenatal Compleat Acti-MN + B1 + C Caplet Prenatryl FloraFol Multra Plex Balanced B-100 Timed Release B Complex W C and B12 Inj Multi Vitamin and Fluoride Zintrexyl-C Vol-Nate Stress Forte Plus Lipotropic Factors M.V.I. Paediatric Nutra-clear Se-Natal 19 Chewable Thiamine Hydrochloride Injection, USP DuetDHA Balanced Dermamed Nutrition for troubled skin Essential Vitamins and Minerals MultiVitamin with Fluoride Chewable NovaFerrum Multivitamin with Iron Pediatric Drops Mega 13 Multivitamin Formula Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vit-HA Multi Vitamin and Zinc Supplement Vitafol Plus Balanced B 125 Srt Vol-Tab Rx Pregvit Folic 4 Neo Bex Elixir Vitamin B Complex W C 300mg Tab Grand Master Formula Tab Multiple Vitamins & Minerals Tablets Children's Chewable Multiple Vitamins (chewable Tablets) Thiamine Hydrochloride Biovita Thiamine Hydrochloride Inj 100mg/ml Garfield Chewable Multivitamins Tab V & M Vitamin and Mineral Supplement Vp-heme Ob DHA Childrens Chewable Tab Pregnancy Multivitamin Gemvites Jr Tab Chewable Super Kids Chewable Multivitamin Multimineral (chewable Tablets) RE Nata Vitafol One WestGel DHA Multivitamins Pnv Ob DHA Formula F L W Multi-Vitamin Moms Choice Rx B Complex W Vitamin C Fortis Cap Xvite B Plus C 300mg Timed Release TL-Care DHA Derma-force Xyzbac G Obstetrix DHA Combo Pack Vita-B Extra Once A Day Bev B-150 Supplement De Multivitamines Infusion Arome Fruits Rouges One A Day Advance Adults 50+ Multivitamin with Fluoride Multi-vitamin Dietary Supplement L.G.I.T. RE Prenatal Multivitamin with Iron Card-floe II Tab Kanga Sport Vitamins B & C Plus Minerals Timed Release B Complex 100 Srt Complete Multivitamins and Minerals for Children Lysamine Diet Supp Amp-tab Super Stress Mega B Plus 1000mg Vit C Tab Virt-Caps Childrens Chewable Multiple Vitamins Tab Vital Be-100 Multicaps Vitamin B Complex + C 600mg Tab Multiple Vitamins W Minerals Tab Vitafol Caplet Beminal 500 Tab Cavan Heme OB Multi Nt-OX Liqui Vita Sopalamine 3b Plus Duet DHA 400 ec P.N.P. Vitamin Drink C. Vit-min Formula B-complex Tablets Diaplex Multi-Vitamin Fluoride RE FAC-x Vita-Rx Diabetic Vitamin Obstetrix EC Vitamin & Mineral Formula 1 Dietary Supplement Am Caps Folika-NC PR Natal 430 ec Cavan Folate OB Hylavite PR Natal 400 ec Paramettes Syrup Acti-thiamine Caplet 100mg Nrg Plus Liq Stress B & C Caplet B1 400mg Ctr Tab Children Choice Multivit Chewable Tab Virt-Advance Hi Potency Stress B Tension With C Prenatal Vitamins and Minerals Tablets Prenatal Plus Iron Puralor Trinatal Rx 1 DaVITE MultiVitamin, Iron and Fluoride Drops Virt-Vite Plus Vitamin B1 100 mg Carbassist Tablets Thiamine Vitamin B1 100mg Prenatal Vitamin and Mineral Supplement Flintstones Multiple Vitamins Plus Iron Vitaday Tab Pro His Mint Multi-Nate 30 Stress Formula B-comp + 500mg Vit C Tab OBTREX DHA Combo Pack Multi-vitamins Pnv-VP-U C-force One Daily Vitamin and Mineral Dietary Supplement Methaver Myhephron Dialysis and Stress Supplement Childrens Chewable Multiple Vitamins Beminal With C Fortis Pws Classic Swiss One 10 Multivitamin and Mineral Tab Multi-Vitamin Drops with Fluoride and Iron Stress Formula Everyday Multiple Vitamins M.V.I.-12 Chewable Children's Complete Multivitamins With Essential Minerals Megavite Rx PNV Ferrous Fumarate Docusate Folic Acid Chewable Multiple Vit Plus Iron for Children Stress Vitamin B With C Complex Tablets Dexivite B Compound 50mg Tab Vitamin B Compound With Vitamin C Fortis Capsule Dtc Flinstones Multiple Plus Iron Bugs Bunny and Friends Multiple Vitamins Harvest Of Values All B Complex Tab Mvc 9 Plus 3 Inj Spectrum 2 Cap B Complex W C Forte Cap Keylosa Prenara Adeks Tablets One Tablet Daily Mens Formula Stressmates Cavan Prenatal Vitrexate FE WesTab Plus Ribotin-E Formula Lf CitraNatal Rx O-Cal FA multivitamin Inatal Advance Alsimine W Vitamins A D Multi Enfants Tab Prenatal Supplement - Tab Sopalamine/3b Plus C Sun-rype Vitaburst Supravite 10ml Ampoule Multivit-liq Opti-manganese + B1 + C Caplet Vol-Care Rx B-complex With Vitamin C, Biotin, Folic Acid Multi Vite Liq Junior Stress Ctr Srt Multiple Vitamins - Tablet Mangadyn Multivitamins and Minerals With Betacarotene Tablets Tricare Prenatal DHA One With Folate Cavan-EC SOD DHA Glyco-aide Tab Multi II IV Vi Tab Multivitamin & Minerals (iron Free) Elite OB Prenatal Multivitamin PNV-First Cal M Tab Dialyvite 5000 Thiamine HCl Tab 50mg TriStart DHA PROTECT IRON Liquid Vit B Complex Ctr Supravite Stress Avec Vit E Vitaday Junior Tab Vitamin B Tablets Vitachrom Gc Animal Shapes Tricare Prenatal DHA One Rx Multivitamin Multiple Vitamin Plus Minerals Tab Virt Vite GT Vita B Complex Tab K.L. Vitamin-mineral Natavite Vitamin B1 Tab 100mg Betaxin Alertonic Biovim Tab For Kids Only Chewable Multivit. Plus Iron Vitaphil DHA Bugs Bunny Chew Multi Vit Plus Iron Medi Msm (methyl Sulfonyl Methane) Mor-vites Tab Multivitamin with 0.25 mg Fluoride Paramettes Chewable Multivitamins Plus Iron VitaPhil Aide C-Nate DHA PureVit DualFe Plus Balanced B-100 B-complex Vitamins Tab Folika-V Super Daily No 2 Vp-pnv-dha Zavitrol Folet DHA Childrens Chewab Vitamin W Chel Minerals Vitamin B1 Tablets 100mg Vitamines Et Mineraux Enfants 970 Vitamin B Complex Tab Trinatal GT Escavite Lq Daily Balance Tab Usana Megavitamin Tablets - Tab Chewable Multivitamins Plus Iron B C Antistress Cap Vitamin B1 One A Day Advance Fem Stress Formula Vit B With C Complex Children's Chewable With Iron
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682