DrugBank ID DB00878 Name Chlorhexidine Groups vet_approved withdrawn approved Description Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.[L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today.[A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.[A190453] Topical chlorhexidine for disinfection, as well as oral rinses for dental use, carries activity against a broad range of pathogens including bacteria, yeasts, and viruses.[L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s.[L11572] The FDA withdrew its approval for the use of chlorhexidine gluconate topical tincture 0.5%, due to a significant number of reports concerning chemical and thermal burns associated with the use of this product.[L43942,L44027] Other formulations of chlorhexidine continue to be available. Synonyms Chlorhexidine acetate Cloresidina Chlorhexidine Chlorhexidinum 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)
Chlorhexidin Chlorhexidine hydrochloride Chlorhexidine gluconate Clorhexidina N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide more Brand Names Hibitane Skin Cleanser 4% PerioChip Antiseptic Skin Cleanser Rougier Vap-chlorhexidine Gluconate 2% W/V Zedoary Oils Feminine Antibacterial Gels
Halyard Chlorhexidine Gluconate Pre-Scrub II Surgical Hand Scrub Chlorhexidine Liq 0.05% JIANLIANG Antibacterial Sprays 10mL Chinese Herb Essence Bacteriostatic Feminine Wash Yu Ding Antibacterial Sprays 10mL Akilspray Hand Sanitizer PS1 Aciurgy Pack Scrub-Stat Serdaen Purell Antimicrobial Foam Handwash 2% Chg Loris I.V. Pro - Swabstick Surgical and healthcare personnel hand antiseptic with moisturizers Chlorhexidine Gluconate Solution 0.05% Periogard (Chlorhexidine Gluconate) Steri-stat Tincture (tinted) Antis Prep Gel DermacinRx Surgical ComboPak Solunet C Brosse 4% Dexidin Liq 4% Disinfectant Wet Tissues Burn O Sol Spray E-Z Scrub Antimicrobial Foam Solution Containing 4% Chg Foaming Hand Wash Bactoshield Chg 4% Chlorhexidine 4% Antiseptic Hand Wash Foster and Thrive Noble 75% Alcohol Wipes Scrub-stat IV 4% Plant Herb Based Bacteriostatic Feminine Wash Baxedin Liq 20% QCare Rx Oral Cleansing and Suctioning System, Q4 Germi-stat Prep Gel Hibiclens Antiseptic/antimicrobial Skin Cleanser Loris 2% Chg Solution Major Oral Rinse Disinfectant Spray(Speedy effect type) Savlodil Betalido-C Stanhexidine 20% Chlorhexidine 2% Antiseptic Hand Wash Germi-stat 2% Foaming Liquid Hygienium PMS-chlorhexidine Hand Sanitizer Cida-stat Liq Gelato Chlorohexidine Spectro Tar Antiseptic Shampoo Hibistat Germicidal Hand Rinse Antiseptic Lotion Soap 2% Chlorhexidine-cetrimide Soltn Conc Germi Stat Gel 2% Stanhexidine 4% With Isopropyl Alcohol 4% Scrub Care Protective Hand Loris I.V. Pro - Sponge Acclean Chlorhexidine Gluconate 0.12% Oral Rinse Soluprep Qd Solution X-pur Chlorhexidine Purell Antimicrobial Foam DermacinRx Clorhexacin Soluprep AQ Sponge Chlorhexidine and Isopropyl Alcohol Swabsticks Soluprep AQ Applicator Surgical Continuum System Antibacterial Protective Hand Dermsafe Pc Hospicare 40R Adult Body Wipes Euro-chlorhexidine Antiseptic Solution Soft Care Antiseptic Hand Soap Steri-clean Hexifoam-skin Disinfectant Aer 1% Scrub, Scrub-Stat, Foam Safe, Micro-Guard ChloraPrep One-Step Chlorhexseptic-liq 0.5mg/ml Gum Paroex Scrub Care Exidine -4 CHG Smart Sense Antiseptic Skin Cleanser Hibiclens Hygienipak 4% Chg Foaming Skin Cleanser Steri-stat Liq 20% Dexidin 2 Detergent Antimicrobial Foam Handwash CLIP Liquid Sanitizer Scrub Care Surgical Scrub Brush/nail Cleaner With Exidine 4 Sunberry Rinse free Hand Sanitizer Septi-san Ezy-TM Soluprep Ld Sponge Hibistat Sky Oral Rinse Stat Touch 2 Antimicrobial Skin Cleanser Ostar Antimicrobial Hand Soap 2% - Liquid Hygenipak 2% Chg Foaming Skin Cleanser Rougier Clean Derm HandSoap Scrub, Scrub-Stat Skinvisible Chlorhexidine Formula Hand Sanitizer Lotion Antiseptic Body Cleanser Q2 Oral Care Kit with CHG Avagard Chg NUPRO Chlorhexidine Gluconate Skin antisepsis, oral cleansing, nasal antisepsis Dyna-hex 4 Perioselect Antimicrobial Sol 0.12% Microban Medical Ic-gel BD E-Z Scrub 107 B-good Hand and Skin Disinfecting Agent Hibitane Skin Cleanser Liq 4% Quick-drying rinse-free hand skin disinfectant Dermawerx Surgical PrePak CliniClean Chlorhexidine Gluconate Applicator Salvesept Crm Akilgeld Hand Sanitizer Rouhex G 20% Baxedin Selpak Antibacterial Wet Wipes Laura Line Chlorhexidine Antiseptic Soap Loris 2% Chg Body Cleanser/nettoyant Pour Le Corps Provon Antiseptic Lotion Soap With 2% Chg Sanital Antibacterial Hand Soap Dyna-Hex 2 Prevantics Swab DASH Chlorhexidine Gluconate 0.12% Oral Rinse Hibidil 3M SoluPrep S Chloraprep Loris 2% Chg Wipe/serviette Chlorhexidine Solution Denti-Care Denti-Rinse Chlorhexidine Gluconate Oral Rinse Wart removal Chlorhexidine Gluconate Dr. Zheng s acteriostatic gel DEQGEL Advanced Hand Sanitizer Oral Cleansing and Suctioning System, q2 Antiseptic Cleansing Wipes Hexirex Antiseptic Skin Cleanser 3m Soluprep Sponge Chlora-cleanze Scrub Stat 4 Foam Liq Foaming Hand Antiseptic With Chg 2% WhyteDerm SurgiPak Chloraprep Liq 0.5% 3M Avagard Freeman Packing Alcohol Wipe Spray On Plastic Bandage Non-aerosol Bactigras Chlorhexidine 0.5% Liq Purell CS Foam Handwash 2% CHG Foam Care Chg Surgical Hand Scrub Chlorhexidine Gluconate Solution 0.75% Antiseptic Loris - I.V. Cardinal Health Antiseptic First Aid Spray Steri-stat Liq 4.0% Spray On Plastic Bandage Aerosol Provon Antimicrobial Foam Handwash SANIDEP Advanced Sanitizer with Organic Extracts Bactoshield Chg 2% E-Z Scrub 747 4% Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System Stanhexidine Aqueous 2% With 4% Isopropyl Alcohol Dexlido M-C Laura Line Antibacterial Cream Soap 2% Foaming Chlorhexidine Gluconate Chlorhexidine gluconate Flamazine C Pre-moistened Towelette Hibitane Skin Cleanser 2% Ultrastat Soluprep Antiseptic Skin Cleanser Preoperative Kit Antiseptic Foam Handwash HYDROGEL ESSENCE Antimicrobial Virginal Gel. PMS-chlorhexidine Without Alcohol ReadyPrep CHG Chlorhexidine Gluconate, 0.12% Oral Rinse Mlk F4-C Oronine H Ointment 1% (Fruli) Quick-Dry Disposable Hand Sanitizer CleanCare Chlorhexidine Gluconate 0.12% Oral Rinse DermacinRx Surgical PharmaPak Aplicare Chlorhexidine Gluconate 2% Solution Chlorhexidine and Isopropyl Alcohol Prep Pads Hands-free skin sanitizer Alcohol Antibacterial Wipes Antimicrobial Skin Cleanser Aplicare Antiseptic Chlorhexidine Gluconate Calgon Vestal 4% Chg Antimicrob.skin Cleans. Quick-Drying Hand Sanitizer Endure 400 Scrub-Stat 4 Bioprep Avidene Surgical Scrub Rugby Antiseptic Skin Cleanser Bactoshield CHG Chlorhexidine Gluconate Hygenipak 2% Chg Skin Cleanser QCare Rx Petite Oral Cleansing and Suctioning System Scrub Instillagel Germi Stat Gel 4% Liszt Hand sanitizer without washing Sterixin 0.05% Soluprep PhysiciansCare Eyewash Station Additive Concentrate Wart Remover Ointment. Liquivida Hydration First Aid Antiseptic Skin Cleanser Endure 420 Cida-Stat Bactoshield Rouhex G 4% Betasept Bioprep Liq Prevora Stage 1 Medifresh Hand Skin Antiseptic Disinfectant Wet Wipes Antiseptic Skin Cleanser Exidine-2 CHG Loris I.V. Pro - Prefilled Applicator With Solution Dyna-hex 2 Hibiclens for Georgia Pacific Dyural 80 LM-C Chlorhexidine Alcohol Free Hand Sanitizer Gel Biokaab Dexidin 0.5 Solution Soluprep AQ Maxiclens Chlorhexidine gluconate Liquid Solution, 4% Tai Yu Ling Antibacterial Sprays 10mL Bei Ling Tong Bao Er Zheng Yuan Antibacterial Creams Dr. Luke Molluscum Wart Remover Cida-stat Foam KleerSight 3M SoluPrep Dr. Luke Wart Remover Soluprep Qd Swab KIMVENT ORAL CARE Q4 Kit WITH CHG Chlorhexidine Gluconante Dermawerx Surgical Plus Pak Soft Care 2% Chg Antimicrobial Skin Cleanser Rouhex G Liq 2% Pro-dentx Chlorhexidene Oral Rinse Hygienipak 4% Chg Skin Cleanser Soluprep Qd Wipe Stanhexidine 2% With Isopropyl Alcohol 4% Wart Removal Pen (Qiqing) Chlorhexidine Gluconate Alcohol Disinfectant Periogard Alcohol Free Bacti-stat Chg Chlorhexidine Gluconate Solution USP 20% QCare Rx Oral Cleansing and Suctioning System, Q2 Periogard Peridex Hibitane Skin Cleanser Oro-clense ChloraPrep Swabstick Foam Safe Chlorhexidine Gluconate 0.12% Oral Rinse SAITENM Health Wet wipes Seaqua X Jisberry Hand Sanitizer Spectro Gram 2 Skin Cleanser Dexidin 2 Solution LARA MED Antibacterial Wet Wipes Kimvent Oral Care Q2 Kit with CHG E-Z Scrub 107 QCare Rx Oral Cleansing and Suctioning System Bactoshield CHG Soluprep AQ Swab Hand Wipes Oral Cleansing and Suctioning System, q4 Zappy Ultimate Antiseptic Wipes Antiseptic Cleanser Solution Denticare Chlorhexidine Gluconate Oral Rinse 0.12% Soluprep Applicator Dyural LM- C Chlorhexidine Gluconate, 0.12% Oral Rinse Solution Smart San CHG Peridex Oral Rinse 0.12% Baxedin 2% - 70% Anti-bac Hand Prevantics Swabstick Purmist Dr. Dean Soluprep Swab Anti Mucedine Feminine Wash Scrub Care Exidine-2 CHG Hand wipes Soluprep Antiseptic Skin Cleanser Sponge Soluprep Wipe Peridex Oral Rinse Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% Oris Chx PS2 Aciurgy Pack Stanhexidine Red Tincture 0.5% Eyewash Station Additive Concentrate Disinfectant Fabric Wash Chloraprep Swabsticks Sterigel Plus Steri-stat Liq 2.0% Germi-stat 0.5% Antiseptic Prep Gel Chlorhexidine Savlon Hospital Concentrate Paroex Motherwort Herb Feminine Antibacterial Gels Oro Clear Prevantics swabstick Baxedin Pre-OP ICEKING Skin Expert Refreshing Body Roller BD E-Z Scrub Dyna-Hex 75 Henry Schein Antimicrobial Skin Cleanser Soluprep AQ Wipe Pre and Post Sx Pouch Dyna-Hex 4 Bactoshield CHG Chlorhexidine Gluconate Solution Chlorhexidine Gluconate 0.12% Oral Rinse, USP Alcohol Disinfectant Wipes Calgon Vestal 2% Chg Antimicrob.skin Cleans. Cardinal Health Antiseptic Skin Cleanser Hand Sanitizer Biokaab Hexicinide Dexidin 20 Prevantics Maxi Swabstick Dermsafe Chlorhexidine Gluconate Hand Sanitizer Lotion Chlorhexidine Gluconate Oral Rinse NuSurgePak Surgical Prep/CarePak more Indication Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures.[L11518,L11521,L11527,L11533] Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis[L11512] and a slow-release "chip" which is inserted into periodontal pockets and is indicated for the reduction of pocket depth in adult patients with periodontitis as an adjunct therapy to dental scaling and root planing procedures.[L11536] Categories Alimentary Tract and Metabolism Amidines Anti-Infective Agents Anti-Infective Agents, Local Antiinfectives and Antiseptics for Local Oral Treatment
Antiseptics and Disinfectants Biguanides Biguanides and Amidines Compounds used in a research, industrial, or household setting Decreased Cell Wall Integrity Dental Agents Dermatologicals Disinfectants Guanidines Household Products Irrigating Solutions Medicated Dressings Medicated Dressings With Antiinfectives Miscellaneous Anti-infectives Miscellaneous Local Anti-infectives Mouthwashes Mouthwashes and Gargles Ophthalmological and Otological Preparations Ophthalmologicals Otologicals Sensory Organs Stomatological Preparations Throat Preparations more ATC-Code more CAS number 55-56-1 
