DrugBank ID DB00878 Name Chlorhexidine Groups vet_approved approved investigational withdrawn Description Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.[L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today.[A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.[A190453] Topical chlorhexidine for disinfection, as well as oral rinses for dental use, carries activity against a broad range of pathogens including bacteria, yeasts, and viruses.[L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s.[L11572] The FDA withdrew its approval for the use of chlorhexidine gluconate topical tincture 0.5%, due to a significant number of reports concerning chemical and thermal burns associated with the use of this product.[L43942,L44027] Other formulations of chlorhexidine continue to be available. Synonyms Chlorhexidine acetate Chlorhexidinum Clorhexidina Chlorhexidin Chlorhexidine
Chlorhexidine hydrochloride N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide Cloresidina 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) Chlorhexidine gluconate more Brand Names Henry Schein Antimicrobial Skin Cleanser Periogard (Chlorhexidine Gluconate) Peridex Prevantics Swabstick Bactigras
Periogard Alcohol Free Surgical Continuum System Spectro Gram 2 Skin Cleanser Savlodil Soluprep Sterigel Plus Soluprep AQ Applicator Sky Oral Rinse Hibitane Skin Cleanser 4% Purell Antimicrobial Foam Handwash 2% Chg Baxedin Liq 20% Chlorhexidine Dyna-hex 2 NuSurgePak Surgical Prep/CarePak Antibacterial Protective Hand Antiseptic Cleanser Solution Soluprep Qd Swab Peridex Oral Rinse Chlorhexidine gluconate Chlorhexidine Gluconate Antiseptic Lotion Soap 2% Dr. Luke Wart Remover Prevantics Swab Bactoshield CHG Scrub Care DermacinRx Surgical ComboPak Chlorhexidine Gluconante Burn O Sol Spray Dyna-Hex 2 Hibitane Skin Cleanser Liq 4% Cida-stat Foam E-Z Scrub 747 4% Aplicare Antiseptic Chlorhexidine Gluconate Dermawerx Surgical PrePak Antiseptic Skin Cleanser Exidine-2 CHG Disinfectant Fabric Wash Dr. Dean Denti-Care Denti-Rinse Chlorhexidine Gluconate Oral Rinse Soft Care 2% Chg Antimicrobial Skin Cleanser WhyteDerm SurgiPak Dexidin 2 Solution Skin antisepsis, oral cleansing, nasal antisepsis SAITENM Health Wet wipes Jisberry Hand Sanitizer Loris 2% Chg Wipe/serviette Spray On Plastic Bandage Aerosol Stanhexidine Red Tincture 0.5% Dyna-hex 4 Laura Line Chlorhexidine Antiseptic Soap Anti-bac Hand Bactoshield CHG Chlorhexidine Gluconate Pre-moistened Towelette Chinese Herb Essence Bacteriostatic Feminine Wash Dexlido M-C Steri-stat Tincture (tinted) Antis Prep Gel Bioprep Liq ClindaCare Akilspray Hand Sanitizer Purell Antimicrobial Foam Scrub Care Exidine-2 CHG Chlorhexidine and Isopropyl Alcohol Swabsticks Liszt Hand sanitizer without washing Laura Line Antibacterial Cream Soap 2% E-Z Scrub 107 Serdaen Chlora-cleanze Oral Cleansing and Suctioning System, q4 Scrub-Stat Loris - I.V. Alcohol Disinfectant Wipes Antiseptic Body Cleanser Chlorhexidine Gluconate Oral Rinse Disinfectant Wet Tissues Plant Herb Based Bacteriostatic Feminine Wash Zappy Ultimate Antiseptic Wipes Hexicinide Purmist Scrub Care Surgical Scrub Brush/nail Cleaner With Exidine 4 Soluprep Qd Wipe Dr. Zheng s acteriostatic gel Provon Antimicrobial Foam Handwash Dexidin 0.5 Solution Foaming Hand Antiseptic With Chg 2% Hand Sanitizer Euro-chlorhexidine Chlorhexidine Gluconate Applicator Rougier Vap-chlorhexidine Gluconate 2% W/V Salvesept Crm Soluprep Applicator Loris I.V. Pro - Swabstick Akilgeld Hand Sanitizer Smart San CHG Oro-clense Chlorhexidine Gluconate, 0.12% Oral Rinse Chlorhexidine Gluconate Solution USP 20% Soluprep AQ Wipe Betasept Cardinal Health Antiseptic Skin Cleanser Steri-clean Peridex Oral Rinse 0.12% Oro Clear Scrub, Scrub-Stat Zedoary Oils Feminine Antibacterial Gels Chlorhexidine 4% Antiseptic Hand Wash Dexidin Liq 4% Bactoshield Chg 2% PerioChip Liquivida Hydration First Aid Antiseptic Skin Cleanser Dermsafe Chlorhexidine Gluconate Hand Sanitizer Lotion PhysiciansCare Eyewash Station Additive Concentrate Mlk F4-C Dexidin 20 Pre and Post Sx Pouch DEQGEL Advanced Hand Sanitizer Hand Sanitizer Biokaab CliniClean HYDROGEL ESSENCE Antimicrobial Virginal Gel. Hibiclens Soluprep Swab Endure 400 Scrub-Stat 4 Germi-stat Prep Gel Gum Paroex Microban Medical Sunberry Rinse free Hand Sanitizer Chlorhexidine Gluconate Solution 0.05% Calgon Vestal 2% Chg Antimicrob.skin Cleans. Chlorhexidine Gluconate, 0.12% Oral Rinse Solution Germi-stat 0.5% Antiseptic Prep Gel Germi Stat Gel 2% Spectro Tar Antiseptic Shampoo Hand Sanitizer Gel Biokaab PS1 Aciurgy Pack Pre-Scrub II Surgical Hand Scrub Q2 Oral Care Kit with CHG Kimvent Oral Care Q2 Kit with CHG X-pur Chlorhexidine B-good Hand and Skin Disinfecting Agent Hexirex Antiseptic Skin Cleanser Dermsafe Pc Ic-gel Instillagel Scrub, Scrub-Stat, Foam Safe, Micro-Guard 3M SoluPrep S Noble 75% Alcohol Wipes Oral Cleansing and Suctioning System, q2 Foaming Chlorhexidine Gluconate Stanhexidine 2% With Isopropyl Alcohol 4% Hexifoam-skin Disinfectant Aer 1% Chloraprep Soluprep Antiseptic Skin Cleanser Sponge Avagard Chg Chlorhexidine Gluconate Solution 0.75% Antiseptic (Fruli) Quick-Dry Disposable Hand Sanitizer Baxedin Pre-OP Chloraprep Liq 0.5% Scrub Care Exidine -4 CHG Bactoshield Chg 4% Hibistat Antimicrobial Skin Cleanser KleerSight QCare Rx Oral Cleansing and Suctioning System, Q2 Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% 3m Soluprep Sponge Sterixin 0.05% Foam Safe Scrub Dermawerx Surgical Plus Pak Bactoshield CHG Chlorhexidine Gluconate Solution Rouhex G 20% Foster and Thrive Septi-san Medifresh Hand Skin Antiseptic Disinfectant Wet Wipes BD E-Z Scrub Periogard Antiseptic Skin Cleanser Stanhexidine 20% Soluprep AQ Sponge QCare Rx Oral Cleansing and Suctioning System, Q4 Hand Wipes Disinfectant Spray(Speedy effect type) Soluprep Qd Solution Rouhex G Liq 2% Quick-drying rinse-free hand skin disinfectant LARA MED Antibacterial Wet Wipes Loris 2% Chg Body Cleanser/nettoyant Pour Le Corps Antiseptic Cleansing Wipes Halyard Chlorhexidine Gluconate Spray On Plastic Bandage Non-aerosol DermacinRx Clorhexacin Scrub Stat 4 Foam Liq Foam Care Chg Surgical Hand Scrub Surgical and healthcare personnel hand antiseptic with moisturizers PMS-chlorhexidine Wart removal Steri-stat Liq 20% ChloraPrep One-Step Orapaz Pro-dentx Chlorhexidene Oral Rinse NUPRO Chlorhexidine Gluconate 3M SoluPrep Rugby Antiseptic Skin Cleanser Soft Care Antiseptic Hand Soap Soluprep Wipe Dexidin 2 Detergent Foaming Hand Wash Aplicare Chlorhexidine Gluconate 2% Solution Calgon Vestal 4% Chg Antimicrob.skin Cleans. Steri-stat Liq 4.0% HandSoap Loris I.V. Pro - Prefilled Applicator With Solution Oris Chx Soluprep Ld Sponge Hand wipes Smart Sense Antiseptic Skin Cleanser Provon Antiseptic Lotion Soap With 2% Chg Baxedin 2% - 70% Protective Hand Chlorhexidine 0.5% Liq Chloraprep Swabsticks Soluprep Antiseptic Skin Cleanser Preoperative Kit Dyural LM- C Soluprep AQ CleanCare Chlorhexidine Gluconate 0.12% Oral Rinse Hygienium MyCuteness Pet Dental Care Water Additive Maxiclens Chlorhexidine gluconate Liquid Solution, 4% Skinvisible Chlorhexidine Formula Hand Sanitizer Lotion Ostar Antimicrobial Hand Soap 2% - Liquid Chlorhexidine Gluconate 0.12% Oral Rinse, USP Prevantics Maxi Swabstick Paroex Gelato Chlorohexidine Hibidil Chlorhexidine and Isopropyl Alcohol Prep Pads PMS-chlorhexidine Without Alcohol Wart Removal Pen Eyewash Station Additive Concentrate Cardinal Health QCare Rx Petite Oral Cleansing and Suctioning System Hibitane Skin Cleanser 2% Dyural 80 LM-C Purell CS Foam Handwash 2% CHG Seaqua X Rougier Clean Derm Hospicare 40R Adult Body Wipes PS2 Aciurgy Pack Antiseptic Foam Handwash Chlorhexidine Alcohol Free Freeman Packing Alcohol Wipe Stat Touch 2 Antimicrobial Skin Cleanser Chlorhexidine Gluconate 0.12% Oral Rinse Bioprep CLIP Liquid Sanitizer SANIDEP Advanced Sanitizer with Organic Extracts BD E-Z Scrub 107 Selpak Antibacterial Wet Wipes Tai Yu Ling Antibacterial Sprays 10mL Antiseptic Solution Prevantics swabstick DASH Chlorhexidine Gluconate 0.12% Oral Rinse Hibiclens for Georgia Pacific Motherwort Herb Feminine Antibacterial Gels Sanital Antibacterial Hand Soap Flamazine C Germi-stat 2% Foaming Liquid Bactoshield ReadyPrep CHG Scrub-stat IV 4% Alcohol Antibacterial Wipes Quick-Drying Hand Sanitizer ChloraPrep Swabstick Bacti-stat Chg Betalido-C (Qiqing) Chlorhexidine Gluconate Alcohol Disinfectant 3M Avagard Endure 420 Cida-Stat Stanhexidine Aqueous 2% With 4% Isopropyl Alcohol DermacinRx Surgical PharmaPak Cida-stat Liq Acclean Chlorhexidine Gluconate 0.12% Oral Rinse Ultrastat Ezy-TM JIANLIANG Antibacterial Sprays 10mL KIMVENT ORAL CARE Q4 Kit WITH CHG Anti Mucedine Feminine Wash Hands-free skin sanitizer Hibitane Skin Cleanser QCare Rx Oral Cleansing and Suctioning System Rouhex G 4% Chlorhexidine 2% Antiseptic Hand Wash Hibiclens Antiseptic/antimicrobial Skin Cleanser Chlorhexidine Liq 0.05% Dyna-Hex 4 Denticare Chlorhexidine Gluconate Oral Rinse 0.12% Antiseptic First Aid Spray Prevora Stage 1 Hygienipak 4% Chg Foaming Skin Cleanser Germi Stat Gel 4% Loris I.V. Pro - Sponge Avidene Surgical Scrub Savlon Hospital Concentrate Bei Ling Tong Bao Er Zheng Yuan Antibacterial Creams ICEKING Skin Expert Refreshing Body Roller Chlorhexidine Solution E-Z Scrub Antimicrobial Foam Solution Containing 4% Chg Antimicrobial Foam Handwash Hygenipak 2% Chg Skin Cleanser Yu Ding Antibacterial Sprays 10mL Dyna-Hex 75 Hygenipak 2% Chg Foaming Skin Cleanser Chlorhexidine-cetrimide Soltn Conc Dr. Luke Molluscum Wart Remover Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System Wart Remover Ointment. Major Oral Rinse Perioselect Antimicrobial Sol 0.12% Solunet C Brosse 4% Hibistat Germicidal Hand Rinse Soluprep AQ Swab Baxedin Oronine H Ointment 1% Stanhexidine 4% With Isopropyl Alcohol 4% Loris 2% Chg Solution Steri-stat Liq 2.0% Hygienipak 4% Chg Skin Cleanser Chlorhexseptic-liq 0.5mg/ml more Indication Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures.[L11518,L11521,L11527,L11533] Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis[L11512] and a slow-release "chip" which is inserted into periodontal pockets and is indicated for the reduction of pocket depth in adult patients with periodontitis as an adjunct therapy to dental scaling and root planing procedures.[L11536] Categories Alimentary Tract and Metabolism Amidines Anti-Infective Agents Anti-Infective Agents, Local Antiinfectives and Antiseptics for Local Oral Treatment
Antiseptics and Disinfectants Biguanides Biguanides and Amidines Compounds used in a research, industrial, or household setting Decreased Cell Wall Integrity Dental Agents Dermatologicals Disinfectants Guanidines Household Products Irrigating Solutions Medicated Dressings Medicated Dressings With Antiinfectives Miscellaneous Anti-infectives Miscellaneous Local Anti-infectives Mouthwashes Mouthwashes and Gargles Ophthalmological and Otological Preparations Ophthalmologicals Otologicals Sensory Organs Stomatological Preparations Throat Preparations more ATC-Code more CAS number 55-56-1 
