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235,183 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Howell, P.L."

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Search Summary

This query matches 137 Structures.

Refinements

Structure Determination Methodology

experimental (137)

Scientific Name of Source Organism

	Escherichia coli (18)
	Pseudomonas aeruginosa PAO1 (18)
	Geobacter metallireducens GS-15 (12)
	Anas platyrhynchos (10)
	Homo sapiens (9)
	Escherichia coli K-12 (8)
	Caulobacter vibrioides NA1000 (5)
	Penicillium citrinum (5)
	Arabidopsis thaliana (4)
	Pseudomonas syringae pv. tomato str. DC3000 (4)

More...

Taxonomy

	Bacteria (93)
	Eukaryota (41)
	Duplodnaviria (2)
	other sequences (1)

Experimental Method

	X-RAY DIFFRACTION (123)
	ELECTRON MICROSCOPY (12)
	SOLUTION NMR (2)
	SOLUTION SCATTERING (1)

Polymer Entity Type

Protein (137)

Refinement Resolution (Å)

	1.0 - 1.5 (3)
	1.5 - 2.0 (38)
	2.0 - 2.5 (57)
	2.5 - 3.0 (19)
	3.0 - 3.5 (8)
	3.5 - 4.0 (1)
	4.0 - 4.5 (7)
	> 4.5 (2)

Release Date

	1990 - 1994 (1)
	1995 - 1999 (5)
	2000 - 2004 (30)
	2005 - 2009 (21)
	2010 - 2014 (22)
	2015 - 2019 (41)
	2020 - 2024 (12)
	2025 - 2029 (5)

Enzyme Classification Name

	Hydrolases (40)
	Lyases (21)
	Transferases (14)
	Isomerases (4)
	Ligases (4)

Membrane Protein Annotation

	mpstruc (4)
	OPM (4)
	PDBTM (4)
	MemProtMD (1)

Symmetry Type

	Asymmetric (59)
	Cyclic (60)
	Dihedral (26)

SCOP Classification

	All alpha proteins (26)
	Alpha and beta proteins (a/b) (31)
	Artifacts (16)
	Alpha and beta proteins (a+b) (9)
	All beta proteins (1)

AllSelected

1 to 25 of 137 Structures

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1A7A \| pdb_00001a7a	Download File View File

STRUCTURE OF HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE: DETERMINATION OF A 30 SELENIUM ATOM SUBSTRUCTURE FROM DATA AT A SINGLE WAVELENGTH

Turner, M.A., Yuan, C.-S., Borchardt, R.T., Hershfield, M.S., Smith, G.D., Howell, P.L.

(1998) Nat Struct Biol 5: 369-376

Released	1999-04-20
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	S-ADENOSYLHOMOCYSTEINE HYDROLASE (protein)
Unique Ligands	ADC, NAD

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1AOS \| pdb_00001aos	Download File View File

HUMAN ARGININOSUCCINATE LYASE

Turner, M.A., Simpson, A., Mcinnes, R.R., Howell, P.L.

(1997) Proc Natl Acad Sci U S A 94: 9063-9068

Released	1998-01-14
Method	X-RAY DIFFRACTION 4.2 Å
Organisms	Homo sapiens
Macromolecule	ARGININOSUCCINATE LYASE (protein)

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1AUW \| pdb_00001auw	Download File View File

H91N DELTA 2 CRYSTALLIN FROM DUCK

Abu-Abed, M., Vallee, F., Howell, P.L.

(1997) Biochemistry 36: 14012-14022

Released	1998-03-18
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Anas platyrhynchos
Macromolecule	DELTA 2 CRYSTALLIN (protein)

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1DCN \| pdb_00001dcn	Download File View File

INACTIVE MUTANT H162N OF DELTA 2 CRYSTALLIN WITH BOUND ARGININOSUCCINATE

Vallee, F., Turner, M.A., Lindley, P., Howell, P.L.

(1999) Biochemistry 38: 2425-2434

Released	1999-04-27
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Anas platyrhynchos
Macromolecule	DELTA 2 CRYSTALLIN (protein)
Unique Ligands	AS1

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1DL2 \| pdb_00001dl2	Download File View File

CRYSTAL STRUCTURE OF CLASS I ALPHA-1,2-MANNOSIDASE FROM SACCHAROMYCES CEREVISIAE AT 1.54 ANGSTROM RESOLUTION

Vallee, F., Lipari, F., Yip, P., Herscovics, A., Howell, P.L.

(2000) EMBO J 19: 581-588

Released	2000-02-18
Method	X-RAY DIFFRACTION 1.54 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	CLASS I ALPHA-1,2-MANNOSIDASE (protein)
Unique Ligands	CA, GOL, NAG
Unique branched monosaccharides	BMA, MAN, NAG, NDG

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1FMI \| pdb_00001fmi	Download File View File

CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE

Vallee, F., Karaveg, K., Herscovics, A., Moremen, K.W., Howell, P.L.

(2000) J Biological Chem 275: 41287-41298

Released	2001-01-17
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	ENDOPLASMIC RETICULUM ALPHA-MANNOSIDASE I (protein)
Unique Ligands	CA, SO4

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1FO2 \| pdb_00001fo2	Download File View File

CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH 1-DEOXYMANNOJIRIMYCIN

Vallee, F., Karaveg, K., Moremen, K.W., Herscovics, A., Howell, P.L.

(2000) J Biological Chem 275: 41287-41298

Released	2001-01-17
Method	X-RAY DIFFRACTION 2.38 Å
Organisms	Homo sapiens
Macromolecule	ALPHA1,2-MANNOSIDASE (protein)
Unique Ligands	CA, DMJ, SO4

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1FO3 \| pdb_00001fo3	Download File View File

CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH KIFUNENSINE

Vallee, F., Karaveg, K., Moremen, K.W., Herscovics, A., Howell, P.L.

(2000) J Biological Chem 275: 41287-41298

Released	2001-01-17
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Homo sapiens
Macromolecule	ALPHA1,2-MANNOSIDASE (protein)
Unique Ligands	CA, KIF, SO4

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1HY0 \| pdb_00001hy0	Download File View File

CRYSTAL STRUCTURE OF WILD TYPE DUCK DELTA 1 CRYSTALLIN (EYE LENS PROTEIN)

Sampaleanu, L.M., Vallee, F., Slingsby, C., Howell, P.L.

(2001) Biochemistry 40: 2732-2742

Released	2001-04-21
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Anas platyrhynchos
Macromolecule	DELTA CRYSTALLIN I (protein)
Unique Ligands	SO4

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1HY1 \| pdb_00001hy1	Download File View File

CRYSTAL STRUCTURE OF WILD TYPE DUCK DELTA 2 CRYSTALLIN (EYE LENS PROTEIN)

Sampaleanu, L.M., Vallee, F., Slingsby, C., Howell, P.L.

(2001) Biochemistry 40: 2732-2742

Released	2001-04-21
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Anas platyrhynchos
Macromolecule	DELTA CRYSTALLIN II (protein)

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1I0A \| pdb_00001i0a	Download File View File

CRYSTAL STRUCTURE OF WILD TYPE TURKEY DELTA 1 CRYSTALLIN (EYE LENS PROTEIN)

Sampaleanu, L.M., Vallee, F., Slingsby, C., Howell, P.L.

(2001) Biochemistry 40: 2732-2742

Released	2001-04-21
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Meleagris gallopavo
Macromolecule	DELTA CRYSTALLIN I (protein)

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1JYS \| pdb_00001jys	Download File View File

Crystal Structure of E. coli MTA/AdoHcy Nucleosidase

Lee, J.E., Cornell, K.A., Riscoe, M.K., Howell, P.L.

(2001) Structure 9: 941-953

Released	2002-10-01
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Escherichia coli
Macromolecule	MTA/SAH nucleosidase (protein)
Unique Ligands	ADE

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1K62 \| pdb_00001k62	Download File View File

Crystal Structure of the Human Argininosuccinate Lyase Q286R Mutant

Sampaleanu, L.M., Vallee, F., Thompson, G.D., Howell, P.L.

(2001) Biochemistry 40: 15570-15580

Released	2002-02-01
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Homo sapiens
Macromolecule	Argininosuccinate Lyase (protein)

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1K7W \| pdb_00001k7w	Download File View File

Crystal Structure of S283A Duck Delta 2 Crystallin Mutant

Sampaleanu, L.M., Yu, B., Howell, P.L.

(2002) J Biological Chem 277: 4166-4175

Released	2002-03-06
Method	X-RAY DIFFRACTION 1.96 Å
Organisms	Anas platyrhynchos
Macromolecule	delta 2 crystallin (protein)
Unique Ligands	AS1

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1K92 \| pdb_00001k92	Download File View File

Crystal Structure of Uncomplexed E. coli Argininosuccinate Synthetase

Lemke, C.T., Howell, P.L.

(2001) Structure 9: 1153-1164

Released	2001-12-07
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Escherichia coli
Macromolecule	ARGININOSUCCINATE SYNTHASE (protein)
Unique Ligands	GOL, SO4

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1K97 \| pdb_00001k97	Download File View File

Crystal Structure of E. coli Argininosuccinate Synthetase in complex with Aspartate and Citrulline

Lemke, C.T., Howell, P.L.

(2001) Structure 9: 1153-1164

Released	2001-12-07
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	ARGININOSUCCINATE SYNTHASE (protein)
Unique Ligands	ASP, CIR

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1KKT \| pdb_00001kkt	Download File View File

Structure of P. citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the ER and Golgi Class I enzymes

Lobsanov, Y.D., Vallee, F., Imberty, A., Yoshida, T., Yip, P., Herscovics, A., Howell, P.L.

(2002) J Biological Chem 277: 5620-5630

Released	2002-01-23
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Penicillium citrinum
Macromolecule	Mannosyl-oligosaccharide alpha-1,2-mannosidase (protein)
Unique Ligands	CA
Unique branched monosaccharides	MAN, NAG

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1KP2 \| pdb_00001kp2	Download File View File

Crystal Structure of E. coli Argininosuccinate Synthetase in Complex with ATP

Lemke, C.T., Howell, P.L.

(2002) J Biological Chem 277: 13074-13081

Released	2002-04-17
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	argininosuccinate synthetase (protein)
Unique Ligands	ATP, GAI, PO4

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1KP3 \| pdb_00001kp3	Download File View File

Crystal Structure of E. coli Argininosuccinate Synthetase in Complex with ATP and Citrulline

Lemke, C.T., Howell, P.L.

(2002) J Biological Chem 277: 13074-13081

Released	2002-04-17
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	argininosuccinate synthetase (protein)
Unique Ligands	ATP, CIR, GAI, PO4

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1KRE \| pdb_00001kre	Download File View File

STRUCTURE OF P. CITRINUM ALPHA 1,2-MANNOSIDASE REVEALS THE BASIS FOR DIFFERENCES IN SPECIFICITY OF THE ER AND GOLGI CLASS I ENZYMES

Lobsanov, Y.D., Vallee, F., Imberty, A., Yoshida, T., Yip, P., Herscovics, A., Howell, P.L.

(2002) J Biological Chem 277: 5620-5630

Released	2002-02-20
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Penicillium citrinum
Macromolecule	Mannosyl-oligosaccharide alpha-1,2-mannosidase (protein)
Unique Ligands	CA, DMJ
Unique branched monosaccharides	MAN, NAG

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1KRF \| pdb_00001krf	Download File View File

STRUCTURE OF P. CITRINUM ALPHA 1,2-MANNOSIDASE REVEALS THE BASIS FOR DIFFERENCES IN SPECIFICITY OF THE ER AND GOLGI CLASS I ENZYMES

Lobsanov, Y.D., Vallee, F., Imberty, A., Yoshida, T., Yip, P., Herscovics, A., Howell, P.L.

(2002) J Biological Chem 277: 5620-5630

Released	2002-02-20
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Penicillium citrinum
Macromolecule	Mannosyl-oligosaccharide alpha-1,2-mannosidase (protein)
Unique Ligands	CA, KIF
Unique branched monosaccharides	MAN, NAG

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1LI4 \| pdb_00001li4	Download File View File

Human S-adenosylhomocysteine hydrolase complexed with neplanocin

Yang, X., Hu, Y., Yin, D.H., Turner, M.A., Wang, M., Borchardt, R.T., Howell, P.L., Kuczera, K., Schowen, R.L.

(2003) Biochemistry 42: 1900-1909

Released	2003-05-20
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Homo sapiens
Macromolecule	S-adenosylhomocysteine hydrolase (protein)
Unique Ligands	IPA, NAD, NOC

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1NC1 \| pdb_00001nc1	Download File View File

Crystal structure of E. coli MTA/AdoHcy nucleosidase complexed with 5'-methylthiotubercidin (MTH)

Lee, J.E., Cornell, K.A., Riscoe, M.K., Howell, P.L.

(2003) J Biological Chem 278: 8761-8770

Released	2003-11-25
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	MTA/SAH nucleosidase (protein)
Unique Ligands	MTH

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1NC3 \| pdb_00001nc3	Download File View File

Crystal structure of E. coli MTA/AdoHcy nucleosidase complexed with formycin A (FMA)

Lee, J.E., Cornell, K.A., Riscoe, M.K., Howell, P.L.

(2003) J Biological Chem 278: 8761-8770

Released	2003-03-25
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Escherichia coli
Macromolecule	MTA/SAH nucleosidase (protein)
Unique Ligands	FMC

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1S4N \| pdb_00001s4n	Download File View File

Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p

Lobsanov, Y.D., Romero, P.A., Sleno, B., Yu, B., Yip, P., Herscovics, A., Howell, P.L.

(2004) J Biological Chem 279: 17921-17931

Released	2004-05-04
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Glycolipid 2-alpha-mannosyltransferase (protein)
Unique Ligands	CL, GOL
Unique branched monosaccharides	BMA, MAN, NAG, NDG

1 to 25 of 137 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1A7A | pdb_00001a7a

1AOS | pdb_00001aos

1AUW | pdb_00001auw

1DCN | pdb_00001dcn

1DL2 | pdb_00001dl2

1FMI | pdb_00001fmi

1FO2 | pdb_00001fo2

1FO3 | pdb_00001fo3

1HY0 | pdb_00001hy0

1HY1 | pdb_00001hy1

1I0A | pdb_00001i0a

1JYS | pdb_00001jys

1K62 | pdb_00001k62

1K7W | pdb_00001k7w

1K92 | pdb_00001k92

1K97 | pdb_00001k97

1KKT | pdb_00001kkt

1KP2 | pdb_00001kp2

1KP3 | pdb_00001kp3

1KRE | pdb_00001kre

1KRF | pdb_00001krf

1LI4 | pdb_00001li4

1NC1 | pdb_00001nc1

1NC3 | pdb_00001nc3

1S4N | pdb_00001s4n