QUERY: Structure Author = "Kashima, A."
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Search Summary This query matches 123 Structures.
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1 to 25 of 123 Structures
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1ACJ | pdb_00001acj

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QUATERNARY LIGAND BINDING TO AROMATIC RESIDUES IN THE ACTIVE-SITE GORGE OF ACETYLCHOLINESTERASE

Sussman, J.L., Harel, M., Silman, I.

(1993) Proc Natl Acad Sci U S A 90: 9031-9035

Released1994-08-31
Method
X-RAY DIFFRACTION 2.8 Å
Organisms
Macromolecule
Unique LigandsTHA
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1ACL | pdb_00001acl

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QUATERNARY LIGAND BINDING TO AROMATIC RESIDUES IN THE ACTIVE-SITE GORGE OF ACETYLCHOLINESTERASE

Sussman, J.L., Harel, M., Silman, I.

(1993) Proc Natl Acad Sci U S A 90: 9031-9035

Released1994-08-31
Method
X-RAY DIFFRACTION 2.8 Å
Organisms
Macromolecule
Unique LigandsDME
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1AMN | pdb_00001amn

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TRANSITION STATE ANALOG: ACETYLCHOLINESTERASE COMPLEXED WITH M-(N,N,N-TRIMETHYLAMMONIO)TRIFLUOROACETOPHENONE

Harel, M., Silman, I., Sussman, J.L.

(1996) J Am Chem Soc 118: 2340-2346

Released1996-04-03
Method
X-RAY DIFFRACTION 2.8 Å
Organisms
Macromolecule
Unique LigandsNAF, SO4
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1AX9 | pdb_00001ax9

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ACETYLCHOLINESTERASE COMPLEXED WITH EDROPHONIUM, LAUE DATA

Raves, M.L., Ravelli, R.B.G., Sussman, J.L., Harel, M., Silman, I.

(1998) Acta Crystallogr D Biol Crystallogr 54: 1359-1366

Released1998-02-11
Method
X-RAY DIFFRACTION 2.8 Å
Organisms
Macromolecule
Unique LigandsEDR
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1B41 | pdb_00001b41

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HUMAN ACETYLCHOLINESTERASE COMPLEXED WITH FASCICULIN-II, GLYCOSYLATED PROTEIN

Kryger, G., Harel, M., Shafferman, A., Silman, I., Sussman, J.L.

(2000) Acta Crystallogr D Biol Crystallogr 56: 1385-1394

Released2001-01-17
Method
X-RAY DIFFRACTION 2.76 Å
Organisms
Macromolecule
FASCICULIN-2 (protein)
Unique LigandsNAG
Unique branched monosaccharidesFUC, NAG
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1CFJ | pdb_00001cfj

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METHYLPHOSPHONYLATED ACETYLCHOLINESTERASE (AGED) OBTAINED BY REACTION WITH O-ISOPROPYLMETHYLPHOSPHONOFLUORIDATE (GB, SARIN)

Millard, C.B., Silman, I., Sussman, J.L.

(1999) Biochemistry 38: 7032-7039

Released1999-06-25
Method
X-RAY DIFFRACTION 2.6 Å
Organisms
Macromolecule
Unique LigandsGB, NAG
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1CN1 | pdb_00001cn1

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CRYSTAL STRUCTURE OF DEMETALLIZED CONCANAVALIN A. THE METAL-BINDING REGION

Shoham, M., Yonath, A., Sussman, J.L., Moult, J., Traub, W., Gilboa(Kalb), A.J.

(1979) J Mol Biology 131: 137-155

Released1982-03-04
Method
X-RAY DIFFRACTION 3.2 Å
Organisms
Macromolecule
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1D31 | pdb_00001d31

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THE THREE-DIMENSIONAL STRUCTURES OF BULGE-CONTAINING DNA FRAGMENTS

Joshua-Tor, L., Frolow, F., Appella, E., Hope, H., Rabinovich, D., Sussman, J.L.

(1992) J Mol Biology 225: 397-431

Released1992-04-15
Method
X-RAY DIFFRACTION 2.6 Å
Macromolecule
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1DOI | pdb_00001doi

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2FE-2S FERREDOXIN FROM HALOARCULA MARISMORTUI

Frolow, F., Harel, M., Sussman, J.L., Shoham, M.

(1996) Nat Struct Biol 3: 452-458

Released1996-08-01
Method
X-RAY DIFFRACTION 1.9 Å
Organisms
Macromolecule
Unique LigandsFES, K
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1DX6 | pdb_00001dx6

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STRUCTURE OF ACETYLCHOLINESTERASE COMPLEXED WITH (-)-GALANTHAMINE AT 2.3A RESOLUTION

Greenblatt, H.M., Kryger, G., Lewis, T.T., Silman, I., Sussman, J.L.

(1999) FEBS Lett 463: 321

Released2000-01-02
Method
X-RAY DIFFRACTION 2.3 Å
Organisms
Macromolecule
Unique LigandsGNT, NAG, PG4
Unique branched monosaccharidesNAG
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1E3Q | pdb_00001e3q

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TORPEDO CALIFORNICA ACETYLCHOLINESTERASE COMPLEXED WITH BW284C51

Felder, C.E., Harel, M., Silman, I., Sussman, J.L.

(2002) Acta Crystallogr D Biol Crystallogr 58: 1765

Released2000-07-03
Method
X-RAY DIFFRACTION 2.85 Å
Organisms
Macromolecule
Unique LigandsEBW, NAG, SO4
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1E66 | pdb_00001e66

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STRUCTURE OF ACETYLCHOLINESTERASE COMPLEXED WITH (-)-HUPRINE X AT 2.1A RESOLUTION

Dvir, H., Harel, M., Silman, I., Sussman, J.L.

(2002) Biochemistry 41: 2970

Released2001-08-02
Method
X-RAY DIFFRACTION 2.1 Å
Organisms
Macromolecule
Unique LigandsHUX, NAG
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1EA5 | pdb_00001ea5

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NATIVE ACETYLCHOLINESTERASE (E.C. 3.1.1.7) FROM TORPEDO CALIFORNICA at 1.8A resolution

Harel, M., Weik, M., Silman, I., Sussman, J.L.

(2002) Biochemistry 41: 10810

Released2000-11-08
Method
X-RAY DIFFRACTION 1.8 Å
Organisms
Macromolecule
Unique LigandsNAG
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1EEA | pdb_00001eea

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Acetylcholinesterase

Raves, M.L., Giles, K., Schrag, J.D., Schmid, M.F., Phillips Jr., G.N., Wah, C., Howard, A.J., Silman, I., Sussman, J.L.

(1998) Structure And Function Of Cholinesterases And Related Proteins

Released1999-02-01
Method
X-RAY DIFFRACTION 4.5 Å
Organisms
Macromolecule
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1EVE | pdb_00001eve

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THREE DIMENSIONAL STRUCTURE OF THE ANTI-ALZHEIMER DRUG, E2020 (ARICEPT), COMPLEXED WITH ITS TARGET ACETYLCHOLINESTERASE

Kryger, G., Silman, I., Sussman, J.L.

(1999) Structure 7: 297-307

Released1999-01-20
Method
X-RAY DIFFRACTION 2.5 Å
Organisms
Macromolecule
Unique LigandsE20, NAG
Unique branched monosaccharidesNAG
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1F8U | pdb_00001f8u

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CRYSTAL STRUCTURE OF MUTANT E202Q OF HUMAN ACETYLCHOLINESTERASE COMPLEXED WITH GREEN MAMBA VENOM PEPTIDE FASCICULIN-II

Kryger, G., Harel, M., Shafferman, A., Silman, I., Sussman, J.L.

(2000) Acta Crystallogr D Biol Crystallogr 56: 1385-1394

Released2001-01-17
Method
X-RAY DIFFRACTION 2.9 Å
Organisms
Macromolecule
Unique branched monosaccharidesNAG
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1FSS | pdb_00001fss

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ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH FASCICULIN-II

Harel, M., Kleywegt, G.J., Silman, I., Sussman, J.L.

(1995) Structure 3: 1355-1366

Released1996-03-08
Method
X-RAY DIFFRACTION 3 Å
Organisms
Macromolecule
Unique LigandsNAG, ZN
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1GCD | pdb_00001gcd

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REFINED CRYSTAL STRUCTURE OF "AGED" AND "NON-AGED" ORGANOPHOSPHORYL CONJUGATES OF GAMMA-CHYMOTRYPSIN

Harel, M., Sussman, J.L., Silman, I.

(1991) J Mol Biology 221: 909-918

Released1994-06-22
Method
X-RAY DIFFRACTION 1.9 Å
Organisms
Macromolecule
Unique LigandsDEP, SO4
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1GMH | pdb_00001gmh

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REFINED CRYSTAL STRUCTURE OF "AGED" AND "NON-AGED" ORGANOPHOSPHORYL CONJUGATES OF GAMMA-CHYMOTRYPSIN

Harel, M., Sussman, J.L., Silman, I.

(1991) J Mol Biology 221: 909-918

Released1994-09-30
Method
X-RAY DIFFRACTION 2.1 Å
Organisms
Macromolecule
Unique LigandsISP, SO4
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1GPK | pdb_00001gpk

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Structure of Acetylcholinesterase Complex with (+)-Huperzine A at 2.1A Resolution

Dvir, H., Harel, M., Chetrit, M., Silman, I., Sussman, J.L.

(2002) Biochemistry 41: 10810

Released2002-08-29
Method
X-RAY DIFFRACTION 2.1 Å
Organisms
Macromolecule
Unique LigandsHUP, NAG
Unique branched monosaccharidesNAG
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1GPN | pdb_00001gpn

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STRUCTURE OF ACETYLCHOLINESTERASE COMPLEXED WITH HUPERZINE B AT 2.35A RESOLUTION

Dvir, H., Harel, M., Jiang, H.L., Silman, I., Sussman, J.L.

(2002) Biochemistry 41: 10810

Released2002-08-29
Method
X-RAY DIFFRACTION 2.35 Å
Organisms
Macromolecule
Unique LigandsHUB, NAG
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1GQR | pdb_00001gqr

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ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH RIVASTIGMINE

Raves, M.L., Harel, M., Silman, I., Sussman, J.L.

(2002) Biochemistry 41: 3555

Released2002-03-15
Method
X-RAY DIFFRACTION 2.2 Å
Organisms
Macromolecule
Unique LigandsEMM, NAG, SAF
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1GQS | pdb_00001gqs

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ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH NAP

Bar-on, P., Millard, C.B., Harel, M., Dvir, H., Enz, A., Sussman, J.L., Silman, I.

(2002) Biochemistry 41: 3555

Released2002-03-15
Method
X-RAY DIFFRACTION 3 Å
Organisms
Macromolecule
Unique LigandsNAG, SAF
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1H22 | pdb_00001h22

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Structure of acetylcholinesterase (E.C. 3.1.1.7) complexed with (S,S)-(-)-bis(10)-hupyridone at 2.15A resolution

Wong, D.M., Greenblatt, H.M., Carlier, P.R., Han, Y.-F., Pang, Y.-P., Silman, I., Sussman, J.L.

(2003) J Am Chem Soc 125: 363

Released2002-12-23
Method
X-RAY DIFFRACTION 2.15 Å
Organisms
Macromolecule
Unique LigandsE10, NAG
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1H23 | pdb_00001h23

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Structure of acetylcholinesterase (E.C. 3.1.1.7) complexed with (S,S)-(-)-bis(12)-hupyridone at 2.15A resolution

Wong, D.M., Greenblatt, H.M., Carlier, P.R., Han, Y.F., Pang, Y.P., Silman, I., Sussman, J.L.

(2003) J Am Chem Soc 125: 363

Released2002-12-23
Method
X-RAY DIFFRACTION 2.15 Å
Organisms
Macromolecule
Unique LigandsE12, NAG
1 to 25 of 123 Structures
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