Structure Determination MethodologyScientific Name of Source OrganismRefinement Resolution (Å)Enzyme Classification NameMembrane Protein Annotation | Hollenstein, K., Kean, J., Bortolato, A., Cheng, R.K.Y., Dore, A.S., Jazayeri, A., Cooke, R.M., Weir, M., Marshall, F.H. (2013) Nature 499: 438-443 | Released | 2013-07-17 | | Method | X-RAY DIFFRACTION 2.977 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 1PE, 1Q5, OLA, OLC, PGW, SO4 |
Dore, A.S., Bortolato, A., Hollenstein, K., Cheng, R.K.Y., Read, R.J., Marshall, F.H. (2017) Curr Mol Pharmacol 10: 334-344 | Released | 2016-06-29 | | Method | X-RAY DIFFRACTION 3.183 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 1Q5, OLA, SO4 |
Jazayeri, A., Dore, A.S., Lamb, D., Krishnamurthy, H., Southall, S.M., Baig, A.H., Bortolato, A., Koglin, M., Robertson, N.J., Errey, J.C., Andrews, S.P., Brown, A.J.H., Cooke, R.M., Weir, M., Marshall, F.H. (2016) Nature 533: 274-277 | Released | 2016-04-20 | | Method | X-RAY DIFFRACTION 2.5 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 5MV, OLA, PE5, TLA |
Segala, E., Guo, D., Cheng, R.K.Y., Bortolato, A., Deflorian, F., Dore, A.S., Errey, J.C., Heitman, L.H., Ijzerman, A.P., Marshall, F.H., Cooke, R.M. (2016) J Med Chem 59: 6470-6479 | Released | 2016-06-29 | | Method | X-RAY DIFFRACTION 1.72 Å | | Organisms | | | Macromolecule | | | Unique Ligands | CLR, NA, OLA, OLB, OLC, ZMA |
Segala, E., Guo, D., Cheng, R.K.Y., Bortolato, A., Deflorian, F., Dore, A.S., Errey, J.C., Heitman, L.H., Ijzerman, A.P., Marshall, F.H., Cooke, R.M. (2016) J Med Chem 59: 6470-6479 | Released | 2016-06-29 | | Method | X-RAY DIFFRACTION 1.9 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 6DY, CLR, NA, OLA, OLB, OLC |
Segala, E., Guo, D., Cheng, R.K.Y., Bortolato, A., Deflorian, F., Dore, A.S., Errey, J.C., Heitman, L.H., Ijzerman, A.P., Marshall, F.H., Cooke, R.M. (2016) J Med Chem 59: 6470-6479 | Released | 2016-06-29 | | Method | X-RAY DIFFRACTION 2.002 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 6DZ, CLR, HTO, NA, OLA, OLB, OLC |
Segala, E., Guo, D., Cheng, R.K.Y., Bortolato, A., Deflorian, F., Dore, A.S., Errey, J.C., Heitman, L.H., Ijzerman, A.P., Marshall, F.H., Cooke, R.M. (2016) J Med Chem 59: 6470-6479 | Released | 2016-06-29 | | Method | X-RAY DIFFRACTION 2.2 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 6DX, CLR, NA, OLA, OLB |
Segala, E., Guo, D., Cheng, R.K.Y., Bortolato, A., Deflorian, F., Dore, A.S., Errey, J.C., Heitman, L.H., Ijzerman, A.P., Marshall, F.H., Cooke, R.M. (2016) J Med Chem 59: 6470-6479 | Released | 2016-06-29 | | Method | X-RAY DIFFRACTION 2.1 Å | | Organisms | | | Macromolecule | | | Unique Ligands | 6DV, CLR, NA, OLA, OLB, OLC |
Rappas, M., Jazayeri, A., Brown, A.J.H., Kean, J., Errey, J.C., Robertson, N., Fiez-Vandal, C., Andrews, S.P., Congreve, M., Bortolato, A., Mason, J.S., Baig, A.H., Teobald, I., Dore, A.S., Weir, M., Cooke, R.M., Marshall, F.H. (2017) Nature 546: 254-258 | Released | 2017-06-14 | | Method | X-RAY DIFFRACTION 3.7 Å | | Organisms | | | Macromolecule | | | Unique Ligands | NAG, SOG | | Unique branched monosaccharides | NAG |
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