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1ATG \| pdb_00001atg	Download File View File

AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN

Lawson, D.M., Pau, R.N., Williams, C.E.M., Mitchenall, L.A.

(1998) Structure 6: 1529-1539

Released	1998-10-14
Method	X-RAY DIFFRACTION 1.2 Å
Organisms	Azotobacter vinelandii
Macromolecule	PERIPLASMIC MOLYBDATE-BINDING PROTEIN (protein)
Unique Ligands	ACT, EDO, SO4, WO4

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1H9J \| pdb_00001h9j	Download File View File

Two crystal structures of the cytoplasmic molybdate-binding protein ModG suggest a novel cooperative binding mechanism and provide insights into ligand-binding specificity. Phosphate-grown form with molybdate and phosphate bound

Delarbre, L., Stevenson, C.E.M., White, D.J., Mitchenall, L.A., Pau, R.N., Lawson, D.M.

(2001) J Mol Biology 308: 1063

Released	2001-05-11
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Azotobacter vinelandii
Macromolecule	MOLYBDENUM-BINDING-PROTEIN (protein)
Unique Ligands	MOO, PO4

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1H9K \| pdb_00001h9k	Download File View File

Two crystal structures of the cytoplasmic molybdate-binding protein ModG suggest a novel cooperative binding mechanism and provide insights into ligand-binding specificity. Phosphate-grown form with tungstate and phosphate bound

Delarbre, L., Stevenson, C.E.M., White, D.J., Mitchenall, L.A., Pau, R.N., Lawson, D.M.

(2001) J Mol Biology 308: 1063

Released	2001-05-11
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Azotobacter vinelandii
Macromolecule	MOLYBDENUM-BINDING-PROTEIN (protein)
Unique Ligands	PO4, WO4

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1H9M \| pdb_00001h9m	Download File View File

Two crystal structures of the cytoplasmic molybdate-binding protein ModG suggest a novel cooperative binding mechanism and provide insights into ligand-binding specificity. PEG-grown form with molybdate bound

Delarbre, L., Stevenson, C.E.M., White, D.J., Mitchenall, L.A., Pau, R.N., Lawson, D.M.

(2001) J Mol Biology 308: 1063

Released	2001-05-11
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Azotobacter vinelandii
Macromolecule	MOLYBDENUM-BINDING-PROTEIN (protein)
Unique Ligands	MOO

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2BM4 \| pdb_00002bm4	Download File View File

The Structure of MfpA (Rv3361c, C2 Crystal form). The Pentapeptide Repeat Protein from Mycobacterium tuberculosis Folds as A Right- handed Quadrilateral Beta-helix.

Hegde, S.S., Vetting, M.W., Roderick, S.L., Mitchenall, L.A., Maxwell, A., Takiff, H.E., Blanchard, J.S.

(2005) Science 308: 1480

Released	2005-06-07
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	PENTAPEPTIDE REPEAT FAMILY PROTEIN (protein)

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2BM5 \| pdb_00002bm5	Download File View File

The Structure of MfpA (Rv3361c, P21 Crystal form). The Pentapeptide Repeat Protein from Mycobacterium tuberculosis Folds as A Right- handed Quadrilateral Beta-helix.

Hegde, S.S., Vetting, M.W., Roderick, S.L., Mitchenall, L.A., Maxwell, A., Takiff, H.E., Blanchard, J.S.

(2005) Science 308: 1480

Released	2005-06-07
Method	X-RAY DIFFRACTION 2 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	PENTAPEPTIDE REPEAT FAMILY PROTEIN (protein)
Unique Ligands	SO4

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2BM6 \| pdb_00002bm6	Download File View File

The Structure of MfpA (Rv3361c, C2221 Crystal form). The Pentapeptide Repeat Protein from Mycobacterium tuberculosis Folds as A Right- handed Quadrilateral Beta-helix.

Hegde, S.S., Vetting, M.W., Roderick, S.L., Mitchenall, L.A., Maxwell, A., Takiff, H.E., Blanchard, J.S.

(2005) Science 308: 1480

Released	2005-06-07
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	PENTAPEPTIDE REPEAT FAMILY PROTEIN (protein)
Unique Ligands	CS

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2BM7 \| pdb_00002bm7	Download File View File

The Structure of MfpA (Rv3361c, P3221 Crystal form). The Pentapeptide Repeat Protein from Mycobacterium tuberculosis Folds as A Right- handed Quadrilateral Beta-helix.

Hegde, S.S., Vetting, M.W., Roderick, S.L., Mitchenall, L.A., Maxwell, A., Takiff, H.E., Blanchard, J.S.

(2005) Science 308: 1480

Released	2005-06-07
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Mycobacterium tuberculosis H37Rv
Macromolecule	PENTAPEPTIDE REPEAT FAMILY PROTEIN (protein)

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2Y3P \| pdb_00002y3p	Download File View File

Crystal structure of N-terminal domain of GyrA with the antibiotic simocyclinone D8

Edwards, M.J., Flatman, R.H., Mitchenall, L.A., Stevenson, C.E.M., Le, T.B.K., Clarke, T.A., McKay, A.R., Fiedler, H.-P., Buttner, M.J., Lawson, D.M., Maxwell, A.

(2009) Science 326: 1415

Released	2010-12-29
Method	X-RAY DIFFRACTION 2.62 Å
Organisms	Escherichia coli
Macromolecule	DNA GYRASE SUBUNIT A (protein)
Unique Ligands	MG, SM8

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6Y8L \| pdb_00006y8l	Download File View File

Mycobacterium thermoresistibile GyrB21 in complex with novobiocin

Henderson, S.R., Stevenson, C.E.M., Malone, B., Zholnerovych, Y., Mitchenall, L.A., Pichowicz, M., McGarry, D.H., Cooper, I.R., Charrier, C., Salisbury, A., Lawson, D.M., Maxwell, A.

(2020) J Antimicrob Chemother 75: 2835-2842

Released	2020-08-12
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Mycolicibacterium thermoresistibile
Macromolecule	DNA gyrase subunit B (protein)
Unique Ligands	EDO, NOV, ZN

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6Y8N \| pdb_00006y8n	Download File View File

Mycobacterium thermoresistibile GyrB21 in complex with Redx03863

Henderson, S.R., Stevenson, C.E.M., Malone, B., Zholnerovych, Y., Mitchenall, L.A., Pichowicz, M., McGarry, D.H., Cooper, I.R., Charrier, C., Salisbury, A., Lawson, D.M., Maxwell, A.

(2020) J Antimicrob Chemother 75: 2835-2842

Released	2020-08-12
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Mycolicibacterium thermoresistibile
Macromolecule	DNA gyrase subunit B (protein)
Unique Ligands	EDO, OGH, ZN

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6Y8O \| pdb_00006y8o	Download File View File

Mycobacterium smegmatis GyrB 22kDa ATPase sub-domain in complex with novobiocin

Henderson, S.R., Stevenson, C.E.M., Malone, B., Zholnerovych, Y., Mitchenall, L.A., Pichowicz, M., McGarry, D.H., Cooper, I.R., Charrier, C., Salisbury, A., Lawson, D.M., Maxwell, A.

(2020) J Antimicrob Chemother 75: 2835-2842

Released	2020-08-12
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Mycolicibacterium smegmatis
Macromolecule	DNA gyrase subunit B (protein)
Unique Ligands	ACT, EDO, NA, NOV

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6ZT3 \| pdb_00006zt3	Download File View File

N-terminal 47 kDa fragment of the Mycobacterium smegmatis DNA Gyrase B subunit complexed with ADPNP

Feng, L., Mundy, J.E.A., Stevenson, C.E.M., Mitchenall, L.A., Lawson, D.M., Mi, K., Maxwell, A.

(2021) Proc Natl Acad Sci U S A 118:

Released	2021-03-03
Method	X-RAY DIFFRACTION 1.56 Å
Organisms	Mycolicibacterium smegmatis MC2 155
Macromolecule	DNA gyrase subunit B (protein)
Unique Ligands	ANP, EDO, K, MG, NA

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6ZT4 \| pdb_00006zt4	Download File View File

Pentapeptide repeat protein MfpA from Mycobacterium smegmatis

Feng, L., Mundy, J.E.A., Stevenson, C.E.M., Mitchenall, L.A., Lawson, D.M., Mi, K., Maxwell, A.

(2021) Proc Natl Acad Sci U S A 118:

Released	2021-03-03
Method	X-RAY DIFFRACTION 1.77 Å
Organisms	Mycolicibacterium smegmatis MC2 155
Macromolecule	Pentapeptide repeat protein MfpA (protein)
Unique Ligands	EDO

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6ZT5 \| pdb_00006zt5	Download File View File

Complex between a homodimer of Mycobacterium smegmatis MfpA and a single copy of the N-terminal 47 kDa fragment of the Mycobacterium smegmatis DNA Gyrase B subunit

Feng, L., Mundy, J.E.A., Stevenson, C.E.M., Mitchenall, L.A., Lawson, D.M., Mi, K., Maxwell, A.

(2021) Proc Natl Acad Sci U S A 118:

Released	2021-03-03
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Mycolicibacterium smegmatis MC2 155
Macromolecule	DNA gyrase subunit B (protein) Pentapeptide repeat protein MfpA (protein)
Unique Ligands	SO4

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9FOY \| pdb_00009foy	Download File View File

Ternary complex of a Mycobacterium tuberculosis DNA gyrase core fusion with DNA and the inhibitor AMK32b

Kokot, M., Hrast, M., Feng, L., Mitchenall, L.A., Lawson, D.M., Maxwell, A., Minovski, N., Anderluh, M.

(2024) ACS Med Chem Lett 15: 2164-2170

Released	2024-08-07
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Mycobacterium tuberculosis H37Rv synthetic construct
Macromolecule	DNA gyrase subunit B,DNA gyrase subunit A (protein) DNA (5'-D(APGPCPCPGPTPAPG)-3') (nucleic acid) DNA (5'-D(PGPTPAPCPCPTPAPCPGPGPCPT)-3') (nucleic acid)
Unique Ligands	A1ID8, A1ID9

1ATG | pdb_00001atg

AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN

1H9J | pdb_00001h9j

Two crystal structures of the cytoplasmic molybdate-binding protein ModG suggest a novel cooperative binding mechanism and provide insights into ligand-binding specificity. Phosphate-grown form with molybdate and phosphate bound

1H9K | pdb_00001h9k

Two crystal structures of the cytoplasmic molybdate-binding protein ModG suggest a novel cooperative binding mechanism and provide insights into ligand-binding specificity. Phosphate-grown form with tungstate and phosphate bound

1H9M | pdb_00001h9m

Two crystal structures of the cytoplasmic molybdate-binding protein ModG suggest a novel cooperative binding mechanism and provide insights into ligand-binding specificity. PEG-grown form with molybdate bound

2BM4 | pdb_00002bm4

The Structure of MfpA (Rv3361c, C2 Crystal form). The Pentapeptide Repeat Protein from Mycobacterium tuberculosis Folds as A Right- handed Quadrilateral Beta-helix.

2BM5 | pdb_00002bm5

The Structure of MfpA (Rv3361c, P21 Crystal form). The Pentapeptide Repeat Protein from Mycobacterium tuberculosis Folds as A Right- handed Quadrilateral Beta-helix.

2BM6 | pdb_00002bm6

The Structure of MfpA (Rv3361c, C2221 Crystal form). The Pentapeptide Repeat Protein from Mycobacterium tuberculosis Folds as A Right- handed Quadrilateral Beta-helix.

2BM7 | pdb_00002bm7

The Structure of MfpA (Rv3361c, P3221 Crystal form). The Pentapeptide Repeat Protein from Mycobacterium tuberculosis Folds as A Right- handed Quadrilateral Beta-helix.

2Y3P | pdb_00002y3p

Crystal structure of N-terminal domain of GyrA with the antibiotic simocyclinone D8

6Y8L | pdb_00006y8l

Mycobacterium thermoresistibile GyrB21 in complex with novobiocin

6Y8N | pdb_00006y8n

Mycobacterium thermoresistibile GyrB21 in complex with Redx03863

6Y8O | pdb_00006y8o

Mycobacterium smegmatis GyrB 22kDa ATPase sub-domain in complex with novobiocin

6ZT3 | pdb_00006zt3

N-terminal 47 kDa fragment of the Mycobacterium smegmatis DNA Gyrase B subunit complexed with ADPNP

6ZT4 | pdb_00006zt4

Pentapeptide repeat protein MfpA from Mycobacterium smegmatis

6ZT5 | pdb_00006zt5

Complex between a homodimer of Mycobacterium smegmatis MfpA and a single copy of the N-terminal 47 kDa fragment of the Mycobacterium smegmatis DNA Gyrase B subunit

9FOY | pdb_00009foy

Ternary complex of a Mycobacterium tuberculosis DNA gyrase core fusion with DNA and the inhibitor AMK32b

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Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1ATG | pdb_00001atg

1H9J | pdb_00001h9j

1H9K | pdb_00001h9k

1H9M | pdb_00001h9m

2BM4 | pdb_00002bm4

2BM5 | pdb_00002bm5

2BM6 | pdb_00002bm6

2BM7 | pdb_00002bm7

2Y3P | pdb_00002y3p

6Y8L | pdb_00006y8l

6Y8N | pdb_00006y8n

6Y8O | pdb_00006y8o

6ZT3 | pdb_00006zt3

6ZT4 | pdb_00006zt4

6ZT5 | pdb_00006zt5

9FOY | pdb_00009foy