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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Renatus, M."

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Search Summary

This query matches 44 Structures.

Refinements

Structure Determination Methodology

experimental (44)

Scientific Name of Source Organism

	Homo sapiens (39)
	Bacillus anthracis (2)
	Bos taurus (1)
	Cowpox virus (1)
	Desmodus rotundus (1)
	Mus musculus (1)
	dengue virus type 2 (1)

Taxonomy

	Eukaryota (40)
	Eukaryota (eukaryotes) (3)
	Bacteria (2)
	Riboviria (1)
	Varidnaviria (1)

Experimental Method

X-RAY DIFFRACTION (44)

Polymer Entity Type

Protein (44)

Refinement Resolution (Å)

	1.0 - 1.5 (6)
	1.5 - 2.0 (5)
	2.0 - 2.5 (17)
	2.5 - 3.0 (12)
	3.0 - 3.5 (3)
	3.5 - 4.0 (1)

Release Date

	1995 - 1999 (4)
	2000 - 2004 (7)
	2005 - 2009 (3)
	2010 - 2014 (3)
	2015 - 2019 (5)
	2020 - 2024 (22)

Enzyme Classification Name

	Hydrolases (29)
	Transferases (14)

Symmetry Type

	Asymmetric (33)
	Cyclic (12)
	Dihedral (1)

SCOP Classification

	All beta proteins (10)
	Small proteins (4)
	Alpha and beta proteins (a+b) (3)
	Alpha and beta proteins (a/b) (2)
	Artifacts (2)
	Multi-domain proteins (alpha and beta) (1)

AllSelected

1 to 25 of 44 Structures

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1A5H \| pdb_00001a5h	Download File View File

CATALYTIC DOMAIN OF HUMAN TWO-CHAIN TISSUE PLASMINOGEN ACTIVATOR COMPLEX OF A BIS-BENZAMIDINE

Renatus, M., Bode, W., Stubbs, M.T.

(1997) J Biological Chem 272: 21713-21719

Released	1999-04-20
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	TISSUE PLASMINOGEN ACTIVATOR (protein)
Unique Ligands	BBA

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1A5I \| pdb_00001a5i	Download File View File

CATALYTIC DOMAIN OF VAMPIRE BAT (DESMODUS ROTUNDUS) SALIVA PLASMINOGEN ACTIVATOR IN COMPLEX WITH EGR-CMK (GLU-GLY-ARG CHLOROMETHYL KETONE)

Renatus, M., Stubbs, M.T., Bode, W.

(1997) Biochemistry 36: 13483-13493

Released	1999-03-23
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Desmodus rotundus
Macromolecule	PLASMINOGEN ACTIVATOR (protein)
Unique Ligands	0GJ

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1BDA \| pdb_00001bda	Download File View File

CATALYTIC DOMAIN OF HUMAN SINGLE CHAIN TISSUE PLASMINOGEN ACTIVATOR IN COMPLEX WITH DANSYL-EGR-CMK (DANSYL-GLU-GLY-ARG CHLOROMETHYL KETONE)

Bode, W., Renatus, M., Engh, R.A.

(1997) EMBO J 16: 4797-4805

Released	1999-05-11
Method	X-RAY DIFFRACTION 3.35 Å
Organisms	Homo sapiens
Macromolecule	SINGLE CHAIN TISSUE TYPE PLASMINOGEN ACTIVATOR (protein)
Unique Ligands	2Z0

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1F0C \| pdb_00001f0c	Download File View File

STRUCTURE OF THE VIRAL SERPIN CRMA

Renatus, M., Zhou, Q., Stennicke, H.R., Snipas, S.J., Turk, D., Bankston, L.A., Liddington, R.C., Salvesen, G.S.

(2000) Structure 8: 789-797

Released	2000-09-06
Method	X-RAY DIFFRACTION 2.26 Å
Organisms	Cowpox virus
Macromolecule	ICE INHIBITOR (protein)
Unique Ligands	DTT

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1I3O \| pdb_00001i3o	Download File View File

CRYSTAL STRUCTURE OF THE COMPLEX OF XIAP-BIR2 AND CASPASE 3

Riedl, S.J., Renatus, M., Schwarzenbacher, R., Zhou, Q., Sun, C., Fesik, S.W., Liddington, R.C., Salvesen, G.S.

(2001) Cell 104: 791-800

Released	2001-03-21
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4 (protein) CASPASE 3 (protein)
Unique Ligands	ZN

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1J7N \| pdb_00001j7n	Download File View File

Anthrax Toxin Lethal factor

Pannifer, A.D., Wong, T.Y., Schwarzenbacher, R., Renatus, M., Petosa, C., Collier, R.J., Bienkowska, J., Lacy, D.B., Park, S., Leppla, S.H., Hanna, P., Liddington, R.C.

(2001) Nature 414: 229-233

Released	2001-11-07
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Bacillus anthracis
Macromolecule	Lethal Factor precursor (protein)
Unique Ligands	SO4, ZN

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1JKY \| pdb_00001jky	Download File View File

Crystal Structure of the Anthrax Lethal Factor (LF): Wild-type LF Complexed with the N-terminal Sequence of MAPKK2

Pannifer, A.D., Wong, T.Y., Schwarzenbacher, R., Renatus, M., Petosa, C., Collier, R.J., Bienkowska, J., Lacy, D.B., Park, S., Leppla, S.H., Hanna, P., Liddington, R.C.

(2001) Nature 414: 229-233

Released	2001-11-07
Method	X-RAY DIFFRACTION 3.9 Å
Organisms	Bacillus anthracis Homo sapiens
Macromolecule	Lethal Factor (protein) mitogen-activated protein kinase kinase 2 (protein)

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1JXQ \| pdb_00001jxq	Download File View File

Structure of cleaved, CARD domain deleted Caspase-9

Renatus, M., Stennicke, H.R., Scott, F.L., Liddington, R.C., Salvesen, G.S.

(2001) Proc Natl Acad Sci U S A 98: 14250-14255

Released	2001-12-12
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	Caspase-9 (protein) benzoxycarbonyl-Val-Ala-Asp-fluoromethyl ketone Inhibitor (protein)

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1QUR \| pdb_00001qur	Download File View File

HUMAN ALPHA-THROMBIN IN COMPLEX WITH BIVALENT, BENZAMIDINE-BASED SYNTHETIC INHIBITOR

Renatus, M., Steinmetzer, T.

(1999) Eur J Biochem 265: 598-605

Released	1999-10-14
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	BIVALENT INHIBITOR (BZA-2 HIRULOG) (protein) HUMAN THROMBIN (ALPHA CHAIN) (protein) HUMAN THROMBIN (BETA CHAIN) (protein)

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1XB0 \| pdb_00001xb0	Download File View File

Structure of the BIR domain of IAP-like protein 2

Shin, H., Renatus, M., Eckelman, B.P., Nunes, V.A., Sampaio, C.A.M., Salvesen, G.S.

(2005) Biochem J 385: 1-10

Released	2004-11-02
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	Baculoviral IAP repeat-containing protein 8 (protein) Diablo homolog, mitochondrial (protein)
Unique Ligands	ZN

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1XB1 \| pdb_00001xb1	Download File View File

The Structure of the BIR domain of IAP-like protein 2

Shin, H., Renatus, M., Eckelman, B.P., Nunes, V.A., Sampaio, C.A.M., Salvesen, G.S.

(2005) Biochem J 385: 1-10

Released	2004-11-02
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	Baculoviral IAP repeat-containing protein 8 (protein) Diablo homolog, mitochondrial (protein)
Unique Ligands	ZN

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2FOM \| pdb_00002fom	Download File View File

Dengue Virus NS2B/NS3 Protease

Schiering, N., Kroemer, M., Renatus, M., Erbel, P., D'Arcy, A.

(2006) Nat Struct Mol Biol 13: 372-373

Released	2006-03-07
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	dengue virus type 2
Macromolecule	polyprotein (protein)
Unique Ligands	CL, GOL

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2HD5 \| pdb_00002hd5	Download File View File

USP2 in complex with ubiquitin

Renatus, M., Kroemer, M.

(2006) Structure 14: 1293-1302

Released	2006-08-15
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Bos taurus Homo sapiens
Macromolecule	Polyubiquitin (protein) Ubiquitin carboxyl-terminal hydrolase 2 (protein)
Unique Ligands	ZN

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2WDP \| pdb_00002wdp	Download File View File

Crystal Structure of Ligand Free Human Caspase-6

Baumgartner, R., Briand, C., Meder, G., Morse, R., Renatus, M.

(2009) Biochem J 423: 429

Released	2009-10-27
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	CASPASE-6 (protein)
Unique Ligands	PO4

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3V4L \| pdb_00003v4l	Download File View File

Mouse MALT1(caspase-IG3 domains) in complex with a irreversible peptidic inhibitor

Renatus, M., Wiesmann, C.

(2012) J Mol Biology 419: 4-21

Released	2012-03-14
Method	X-RAY DIFFRACTION 3.15 Å
Organisms	Mus musculus
Macromolecule	MALT1 Inhibitor (protein) Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog (protein)

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3V4O \| pdb_00003v4o	Download File View File

Human MALT1 (caspase domain) in complex with an irreversible peptidic inhibitor

Renatus, M., Wiesmann, C.

(2012) J Mol Biology 419: 4-21

Released	2012-03-14
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	MALT1 Inhibitor (protein) Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (protein)

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3V55 \| pdb_00003v55	Download File View File

Human MALT1 (334-719) in its ligand free form

Renatus, M., Wiesmann, C.

(2012) J Mol Biology 419: 4-21

Released	2012-03-14
Method	X-RAY DIFFRACTION 1.81 Å
Organisms	Homo sapiens
Macromolecule	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (protein)

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5JOG \| pdb_00005jog	Download File View File

CRYSTAL STRUCTURE OF CSN5(2-257) IN COMPLEX WITH CNS5i-3

Renatus, M., Wiesmann, C.

(2016) Nat Commun 7: 13166-13166

Released	2016-11-02
Method	X-RAY DIFFRACTION 2.46 Å
Organisms	Homo sapiens
Macromolecule	COP9 signalosome complex subunit 5 (protein)
Unique Ligands	6LT, ZN

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5JOH \| pdb_00005joh	Download File View File

CRYSTAL STRUCTURE OF CSN5(2-257) IN COMPLEX WITH CNS5i-1b

Renatus, M., Wiesmann, C.

(2016) Nat Commun 7: 13166-13166

Released	2016-11-02
Method	X-RAY DIFFRACTION 1.99 Å
Organisms	Homo sapiens
Macromolecule	COP9 signalosome complex subunit 5 (protein)
Unique Ligands	6M3, MPD, ZN

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5M5Q \| pdb_00005m5q	Download File View File

COPS5(2-257) IN COMPLEX WITH A AZAINDOLE (COMPOUND 4)

Renatus, M., Altmann, E.

(2017) Angew Chem Int Ed Engl 56: 1294-1297

Released	2017-01-11
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	COP9 signalosome complex subunit 5 (protein)
Unique Ligands	7K1, MPD, ZN

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6F7I \| pdb_00006f7i	Download File View File

human MALT1(329-728) IN COMPLEX WITH MLT-747

Renatus, M., Renatus, M.

(2019) Nat Chem Biol 15: 304-313

Released	2019-01-02
Method	X-RAY DIFFRACTION 2.43 Å
Organisms	Homo sapiens
Macromolecule	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (protein)
Unique Ligands	CW5, GOL, MG

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6H4A \| pdb_00006h4a	Download File View File

Human MALT1(329-728) in complex with MLT-748

Renatus, M., Renatus, M.

(2019) Nat Chem Biol 15: 304-313

Released	2019-02-13
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Homo sapiens
Macromolecule	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (protein)
Unique Ligands	FNB